Southeast Collaborative Alliance for Stroke Trials (SE-CoAST)

东南卒中试验合作联盟 (SE-CoAST)

• 批准号: 9762233
• 负责人: TANYA N TURAN
• 金额: $ 31.56万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762233
• 关键词: Academic Medical Centers; Acute; Adult; Area; Awareness; Caring; Catchment Area; Childhood stroke; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Conduct Clinical Trials; Country; Data Collection; Data Quality; Education; Ensure; Environment; Epidemic; Evaluation; Funding; Geographic Locations; Goals; Health; Health Services Accessibility; Health system; Healthcare; Healthcare Systems; Heart; Infrastructure; Interdisciplinary Study; Intervention Studies; Lead; Leadership; Medical; Medical Care Team; Mentors; Multicenter Trials; Neurosciences; Patient Education; Population; Population Heterogeneity; Prevention; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Role; Scientist; Services; South Carolina; Stroke; Stroke Belt; StrokeNet clinical trials; StrokeNet trials; System; Therapeutic Intervention; Training; United States; Universities; Work; base; bioimaging; care delivery; care systems; career; career development; clinical care; experience; health care availability; health care settings; healthcare community; high risk; imaging biomarker; improved; insight; member; mortality; multidisciplinary; new technology; next generation; novel; novel therapeutics; outreach; preclinical trial; programs; recruit; response; rural African American; stroke clinical trials; stroke education; stroke incidence; stroke risk; stroke trials; synergism; tertiary care; translational scientist

The burden of stroke continues to disproportionately impact the Southeast United States – the so-called Stroke Belt. Reaching these populations for stroke education, prevention, acute treatment, rehabilitation, and in particular participation in clinical research, remains a challenge. Developing a highly functional clinical and research multicenter infrastructure to engage these populations at high risk for stroke is critical to change the disproportionate stroke burden. Stroke care and research, from prevention, through acute treatment, and finally through recovery / rehabilitation, are best provided and performed in the context of multidisciplinary healthcare teams. Stroke Systems of Care, integrating healthcare resources across a geographic region, are recognized as best practice, ensuring optimal care within the region. Research is also best performed working within the existing clinical stroke systems of care, capitalizing on areas of alignment – patient education, engagement, stroke awareness in the healthcare community, and awareness of research participation opportunities in all healthcare settings. In this application, the expanded Southeast Collaborative Alliance for Stroke Trials (SE-CoAST) and its investigators remain committed to serving as a Regional Coordinating Center in StrokeNet. SE-CoAST is now an expanded, robust collaboration between 4 tertiary care academic medical centers situated in the heart of the Stroke Belt: the Medical University of South Carolina along the SC coast, the Augusta University in eastern GA, the Greenville Heath System in the upstate of SC, and the Palmetto Health / University of South Carolina Health System in the midlands of SC. The greatest strength of this expanded network is our existing partnerships in research and stroke care delivery. SE-CoAST now serves nearly the entire state of SC and a large proportion of GA, given the breadth of our catchment areas as well as our significant telestroke presence across the Southeast. The overall goals of SE-CoAST remain: 1) to leverage the SE-CoAST organization to increase the number of residents of our states participating in acute, prevention and recovery StrokeNet trials; 2) to continue our leadership roles in StrokeNet activities nationally; 3) to utilize SE-CoAST preclinical researchers in developing promising therapeutic interventions for study within StrokeNet; 4) to continue to support and enhance the career development of our StrokeNet scholars.

中风的负担继续不成比例地影响着美国东南部——所谓的