Southeast Collaborative Alliance for Stroke Trials (SE-CoAST)

东南卒中试验合作联盟 (SE-CoAST)

• 批准号: 10448518
• 负责人: TANYA N TURAN
• 金额: $ 29.65万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10448518
• 关键词: Academic Medical Centers; Acute; Adult; African American population; Area; Awareness; Caring; Catchment Area; Childhood stroke; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Conduct Clinical Trials; Country; Data Collection; Education; Ensure; Environment; Epidemic; Evaluation; Funding; Geographic Locations; Goals; Health; Health Services Accessibility; Health system; Healthcare; Healthcare Systems; Heart; Infrastructure; Interdisciplinary Study; Intervention Studies; Lead; Leadership; Medical; Medical Care Team; Mentors; Multicenter Trials; Neurosciences; Patient Education; Population; Population Heterogeneity; Prevention; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Role; Scientist; Services; South Carolina; Stroke; Stroke Belt; StrokeNet clinical trials; StrokeNet trials; System; Therapeutic Intervention; Training; United States; Universities; Work; base; bioimaging; care delivery; care systems; career; career development; clinical care; experience; health care availability; health care settings; healthcare community; high risk; imaging biomarker; improved; insight; member; mortality; multidisciplinary; new technology; next generation; novel; novel therapeutics; outreach; preclinical trial; programs; recruit; response; rural African American; stroke clinical trials; stroke education; stroke incidence; stroke risk; stroke trials; synergism; telestroke; tertiary care; translational scientist

The burden of stroke continues to disproportionately impact the Southeast United States – the so-called Stroke Belt. Reaching these populations for stroke education, prevention, acute treatment, rehabilitation, and in particular participation in clinical research, remains a challenge. Developing a highly functional clinical and research multicenter infrastructure to engage these populations at high risk for stroke is critical to change the disproportionate stroke burden. Stroke care and research, from prevention, through acute treatment, and finally through recovery / rehabilitation, are best provided and performed in the context of multidisciplinary healthcare teams. Stroke Systems of Care, integrating healthcare resources across a geographic region, are recognized as best practice, ensuring optimal care within the region. Research is also best performed working within the existing clinical stroke systems of care, capitalizing on areas of alignment – patient education, engagement, stroke awareness in the healthcare community, and awareness of research participation opportunities in all healthcare settings. In this application, the expanded Southeast Collaborative Alliance for Stroke Trials (SE-CoAST) and its investigators remain committed to serving as a Regional Coordinating Center in StrokeNet. SE-CoAST is now an expanded, robust collaboration between 4 tertiary care academic medical centers situated in the heart of the Stroke Belt: the Medical University of South Carolina along the SC coast, the Augusta University in eastern GA, the Greenville Heath System in the upstate of SC, and the Palmetto Health / University of South Carolina Health System in the midlands of SC. The greatest strength of this expanded network is our existing partnerships in research and stroke care delivery. SE-CoAST now serves nearly the entire state of SC and a large proportion of GA, given the breadth of our catchment areas as well as our significant telestroke presence across the Southeast. The overall goals of SE-CoAST remain: 1) to leverage the SE-CoAST organization to increase the number of residents of our states participating in acute, prevention and recovery StrokeNet trials; 2) to continue our leadership roles in StrokeNet activities nationally; 3) to utilize SE-CoAST preclinical researchers in developing promising therapeutic interventions for study within StrokeNet; 4) to continue to support and enhance the career development of our StrokeNet scholars.

中风负担继续严重影响美国东南部地区——所谓的中风负担 中风带。向这些人群提供中风教育、预防、急性治疗、康复和康复服务 特别是参与临床研究，仍然是一个挑战。开发功能强大的临床和 研究多中心基础设施以吸引这些中风高危人群的参与对于改变这一现状至关重要 不成比例的中风负担。 中风护理和研究，从预防，到急性治疗，最后到康复/ 康复治疗最好在多学科医疗团队的背景下提供和执行。中风 护理系统整合了整个地理区域的医疗保健资源，被认为是最佳的 实践，确保该地区的最佳护理。研究最好在现有的范围内进行 临床中风护理系统，利用协调领域——患者教育、参与、中风 医疗保健界的意识，以及所有人对研究参与机会的认识 医疗保健设置。 在此应用中，扩大的东南卒中试验合作联盟 (SE-CoAST) 及其 调查人员仍然致力于充当 StrokeNet 的区域协调中心。东南海岸现在 位于市中心的 4 个三级护理学术医疗中心之间扩大、强有力的合作 中风带：南卡罗来纳州海岸沿线的南卡罗来纳医科大学、东部的奥古斯塔大学 乔治亚州、南卡罗来纳州北部的格林维尔希思系统和帕尔梅托健康中心/南卡罗来纳大学 南卡罗来纳州中部的卫生系统。这个扩展网络的最大优势是我们现有的 研究和中风护理服务方面的合作伙伴关系。 SE-CoAST 现在几乎为南卡罗来纳州的整个州提供服务，并且 考虑到我们服务范围的广度以及我们重要的远程攻击存在，GA 所占的比例很大 横跨东南。 SE-CoAST 的总体目标仍然是：1）利用 SE-CoAST 组织 增加我们各州参与急性、预防和恢复 StrokeNet 试验的居民数量； 2) 继续在全国 StrokeNet 活动中发挥领导作用； 3）利用SE-CoAST临床前 研究人员正在开发有前景的治疗干预措施，以便在 StrokeNet 内进行研究； 4）继续 支持并促进 StrokeNet 学者的职业发展。