Mindful Body Awareness Training as an Adjunct to Medication Assisted Treatment for Opioid Use Disorder: An ancillary study
正念身体意识训练作为阿片类药物使用障碍药物辅助治疗的辅助手段:一项辅助研究
基本信息
- 批准号:9893166
- 负责人:
- 金额:$ 223.53万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-28 至 2024-06-30
- 项目状态:已结题
- 来源:
- 关键词:AbstinenceAddressAdherenceAdoptedAdultAffectAffectiveAlcohol or Other Drugs useAmericanAncillary StudyAnxietyAwarenessBehavior TherapyBehavioralBehavioral ResearchBenzodiazepinesBuprenorphineCare given by nursesCase ManagerChronic stressClinicalClinical TrialsCocaineComorbidityComplexDataDevelopmentDistressDoseEffectivenessEpidemicEvidence based treatmentFunctional disorderFundingFutureGoalsHIVHealthHealthcareHepatitis C virusHeroinInteroceptionInterventionMaintenanceMassachusettsMeasuresMedicaidMental DepressionMental HealthMethadoneMethamphetamineMind-Body InterventionModelingMorbidity - disease rateNational Institute of Drug AbuseNeurocognitiveOpioidOutcomeOverdosePainParentsPatient-Focused OutcomesPatientsPersonsPharmaceutical PreparationsPharmacologic SubstancePhysiciansPoliciesPricePrimary Health CarePsyche structureRandomizedRegulationRelapseResearchResearch DesignRoleRuralSample SizeSelf CareSeveritiesSiteStressSubstance Use DisorderSystemTestingTrainingTreatment outcomeUnited StatesUnited States Substance Abuse and Mental Health Services AdministrationVariantWashingtonWell in selfaddictionbasebehavior changebuprenorphine treatmentchronic paincostcravingdepressive symptomsdesigneffective interventionemotion dysregulationemotion regulationevidence baseillicit opioidimprovedinnovationmedication-assisted treatmentmindfulnessmortalitynon-opioid analgesicnovelopioid agonist therapyopioid epidemicopioid overdoseopioid useopioid use disorderphysical conditioningphysical symptomprescription opioidprogramsreduced substance userelapse riskresponserural arearural settingskillssocialsuccesstherapy designtreatment as usualtreatment optimizationtreatment programurban setting
项目摘要
Abstract
The national opioid epidemic requires development of real-world evidence based treatments for
opioid use disorder, including adjuncts to Medication Assisted Treatment (MAT) with
buprenorphine. Interventions are needed that address the complex needs of patients with
opioid use disorder, which include substantial mental health co-morbidity and high rates of
chronic pain related to the complex interaction of opioid prescribing for pain and opioid use
disorder. This study takes advantage of recent federal and state opioid use disorder treatment
initiatives as a platform for testing a promising mind-body intervention, Mindful Awareness in
Body-oriented Therapy (MABT) as an adjunct to MAT in three clinical settings funded through
the Washington Opioid State Targeted Response (STR) program. Each setting employs a
variation of the nationally recognized Massachusetts Nurse Care Manager model. Using a
randomized, repeated measures design, we will compare those who receive MABT+ MAT to
MAT only. The overarching goal of this application is to test MABT to improve MAT outcomes
among patients receiving buprenorphine to treat OUD. The primary aims for this R01 study
extend the final outcome to 12 months, but are otherwise the same as the parent R33. The first
aim is to evaluate the effectiveness of MABT + MAT compared to MAT only (treatment-as-
usual) in reducing opioid use (primary hypothesis) and non-opioid substance use (secondary
hypothesis) at 12 months. Aim 2 will examine the effectiveness of MABT + MAT to improve
mental and physical health distress (i.e. symptoms of depression and anxiety; emotional well-
being, and physical symptoms and pain severity/interference) compared to MAT only at 12
months. Aim 3 will examine the effectiveness of MABT + MAT compared to MAT only to
positively affect substance use related outcomes such as craving and treatment retention at 12
months. An additional exploratory aim (Aim 4) will explore the effectiveness of an increased
MABT dose for MABT non-responders. Results of this study will inform the evidence base for
behavioral treatment adjuncts to MAT with buprenorphine and directly impact the future
direction of opioid use disorder treatment in Washington State.
摘要
项目成果
期刊论文数量(0)
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JOSEPH O MERRILL其他文献
JOSEPH O MERRILL的其他文献
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{{ truncateString('JOSEPH O MERRILL', 18)}}的其他基金
Examining Trauma Prevalence and Exploring Interoception as a Mechanism of Emotion Regulation in MOUD
检查创伤发生率并探索内感受作为 MOUD 情绪调节的机制
- 批准号:
10618645 - 财政年份:2019
- 资助金额:
$ 223.53万 - 项目类别:
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