Examining Trauma Prevalence and Exploring Interoception as a Mechanism of Emotion Regulation in MOUD

检查创伤发生率并探索内感受作为 MOUD 情绪调节的机制

基本信息

  • 批准号:
    10618645
  • 负责人:
  • 金额:
    $ 17.47万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-28 至 2024-06-30
  • 项目状态:
    已结题

项目摘要

Project Abstract The Parent Grant (R01 AT10742; PIs Price & Merrill) is a two-group randomized controlled trial, with repeated measures, designed to enroll a sample of 330 in medication treatment for opioid use disorder (MOUD) to assess the effectiveness of Mindful Awareness in Body-oriented Therapy (MABT) as an adjunct to medication treatment for opioid use disorder (MOUD). The national opioid epidemic requires development of real-world evidence-based treatments for opioid use disorder, including adjuncts to MOUD. Interventions are needed that address the complex needs of patients with opioid use disorder, which include substantial mental health co- morbidity (e.g. PTSD, depression) and high rates of chronic pain. MABT, a novel mindfulness-based intervention, uniquely addresses aspects of awareness, interoception, and regulation that may be associated with pain, mental health distress, and behavioral control that increase risk of relapse and poor treatment outcomes. The proposed Diversity Supplement examines two critical additional research questions. The aims are: 1) to describe the types of lifetime exposure to trauma and compare types of trauma exposure between men and women engaged in MOUD, and to examine the relationship between types of trauma exposure and symptomatic distress in this sample at baseline; and 2) to explore the underlying mechanisms of MABT by examining interoceptive awareness as a possible mediator of emotion regulation difficulties and other indicators of mental health distress. It is hypothesized that emotion regulation difficulties in MABT + TAU compared to TAU only will be mediated by increased interoceptive awareness from baseline to 3-month follow- up. This application thus addresses key gaps in knowledge that are important for consideration in MOUD treatment that may be critical for reducing relapse and improving treatment outcomes.
项目摘要 Parent Grant(R01 AT10742;Pis Price&Merrill)是一项两组随机对照试验,重复 旨在招募330名阿片类药物使用障碍(Moud)药物治疗样本的措施,以 评估正念意识作为药物辅助的身体导向疗法(MABT)的有效性 阿片类药物使用障碍的治疗(Moud)。国家阿片类药物流行需要现实世界的发展 阿片类药物使用障碍的循证治疗,包括穆德的辅助药物。需要采取干预措施, 满足阿片类药物使用障碍患者的复杂需求,其中包括大量的心理健康合作 发病率高(如创伤后应激障碍、抑郁症)和慢性疼痛发生率高。MABT--一种基于正念的新方法 干预,独特地解决了意识、内感和调节方面可能相关的问题 疼痛、精神健康困扰和行为控制会增加复发的风险和治疗不当 结果。拟议的多样性补编审查了两个关键的额外研究问题。目标 1)描述终身创伤暴露的类型,并比较以下创伤暴露的类型 男性和女性从事MUD,并检查创伤暴露类型与 2)通过以下方法探讨MABT的潜在机制 考察内感知觉作为情绪调节困难和其他因素的可能中介 心理健康困扰的指标。MABT+TAU情绪调节困难的假说 与TAU相比,只有从基线到3个月随访期间内感觉意识的增强将起到中介作用 向上。因此,该应用程序解决了在Moud中需要考虑的重要知识差距 可能对减少复发和改善治疗结果至关重要的治疗。

项目成果

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JOSEPH O MERRILL其他文献

JOSEPH O MERRILL的其他文献

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{{ truncateString('JOSEPH O MERRILL', 18)}}的其他基金

Mindful Body Awareness Training as an Adjunct to Medication Assisted Treatment for Opioid Use Disorder: An ancillary study
正念身体意识训练作为阿片类药物使用障碍药物辅助治疗的辅助手段:一项辅助研究
  • 批准号:
    9893166
  • 财政年份:
    2019
  • 资助金额:
    $ 17.47万
  • 项目类别:

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