2/2 Southeast Partnership for Improving Research & Training in Cancer Health Disparities

摘要-行政核心 改善癌症健康差异研究和培训的东南合作伙伴关系（SPIRIT-CHD） 路易斯安那州州立大学健康科学中心（LSUHSC），一个服务不足的机构 人口和代表性不足的学生（IUPS），以及NCI指定的莫菲特癌症中心（MCC）， 关于癌症健康差异的生物学机制的先进转化研究，重点是 生物医学研究和精准医学教育。行政核心（AC）提供 使SPIRIT-CHD发挥作用所需的必要中央监督、协调、支持和后勤 有效地，与持续的沟通和改进是关键的责任。为此，AC 具有以下目标：a）监督规划活动; B）协调和监督试点研究 项目和癌症研究教育计划; c）促进合作者之间的富有成效的互动， 早期研究员（ESI）和学生; d）监测进展并进行组件评估 e）定期审查和修订短期和长期计划; f）确保最高的 所有项目和计划组成部分和活动的科学完整性标准，以及g）激励新的 与健康差距有关的研究合作;以及h）确保方案和核心之间的整合。 AC由一个多学科的既定调查小组领导，由内部顾问指导， 委员会由社区学术成员组成，并得到双方领导层的大力支持 机构职能体系它协同链接并建立在我们与其他PACHE、CURE和社区的经验之上 网络伙伴关系方案。将实施一系列规划和确定优先事项的步骤， 定期和持续的互动，面对面的务虚会和其他沟通渠道，以促进：1）进行 一个试点研究计划开始于一个项目，该项目以乳腺癌基因组学为中心， 来自混合遗传祖先（非洲人、美洲原住民、欧洲人）的拉丁美洲患者的生物标本;以及2） 实施三管齐下的联合癌症研究教育计划，提供本科生和 医学生与暑期研究经验的手，提供课程和重点培训， 学生对生物银行，精准医学和癌症健康的差距，并扩大现有的推广 教育我们各自的种族/少数民族社区。重要的是，AC确保指导 并提供必要的反馈，以实现伙伴关系目标和SPIRIT-CHD的整合 件.总的来说，咨询委员会促进了协调和沟通， 建立互利的机构间伙伴关系， 在癌症相关研究、癌症研究经验和外展教育方面的重点合作。

ABSTRACT – Administrative Core The Southeast Partnership for Improving Research and Training in Cancer Health Disparities (SPIRIT-CHD) unites the Louisiana State University Health Sciences Center (LSUHSC), an institution serving underserved populations and underrepresented students (ISUPS), and the NCI-designated Moffitt Cancer Center (MCC) to advance translational research on the biological mechanisms of cancer health disparities focusing on biospecimen-based research and precision medicine education. The Administrative Core (AC) provides the necessary central oversight, coordination, support and logistics needed to make SPIRIT-CHD function effectively, with ongoing communications and improvements being key responsibilities. To achieve this, the AC has the following objectives: a) oversee planning activities; b) coordinate and monitor the pilot research projects and the cancer research education program; c) foster productive interactions among collaborators, Early Stage Investigators (ESIs), and students; d) monitor progress and conduct evaluations of component sections, e) review and revise short-term and long-range plans on a regular basis; f) ensure the highest standards of scientific integrity for all project and program components and activities, and g) stimulate new research collaborations related to health disparities; and h) ensure integration among the programs and cores. The AC is led by a multidisciplinary team of established investigators, is guided by an Internal Advisory Committee that is comprised of community-academic members, and is highly supported by leadership of both institutions. It synergistically links and builds on our experiences with other PACHE, CURE, and Community Network Partnership Programs. A series of planning and priority-setting steps will be implemented to establish regular and ongoing interactions, in-person retreats, and other communication channels to facilitate: 1) conduct of a pilot research program beginning with a project centered on breast cancer genomics utilizing breast cancer biospecimens from Latina patients of mixed genetic ancestry (African, Native American, European); and 2) implementation of a three-pronged joint Cancer Research Education Program that provides undergraduate and medical students with a hands on summer research experience, delivers a curriculum and focused training to the students on biobanking, precision medicine and cancer health disparities and expands existing outreach education to our respective racial/ethnic minorities communities. Importantly, the AC ensures that guidance and feedback are provided as necessary to achieve partnership goals and integration of SPIRIT-CHD components. Overall, the AC facilitates the coordination and communication necessary for a seamless and mutually beneficial inter-institutional partnership to advance the feasibility, planning and implementation of focused collaborations in cancer-related research, cancer research experience and outreach education.