Accelerated public health and biomedical research on priority public health objectives through collaboration between US NIH and WHO

摘要 世界卫生组织（世卫组织）是卫生事务方面的全球牵头机构。它实现了一个 制定全球卫生规范和标准以及提供技术援助的双重任务 向成员国提供援助。最近，世卫组织在突发卫生事件中的行动 作为一个重要的额外优先事项。健康研究是一项重要的 它在所有工作领域的组成部分，其在研究中的作用最近得到了重申， 世界卫生大会。 为了实现其与研究相关的目标，世卫组织与 政府和其他研究组织在世界各地，作为证明， 世卫组织合作中心网络。世卫组织通过广泛的 补充国家卫生研究院专门机构的目标，包括传染性和非传染性疾病， 传染病、地方病、流行病以及新出现的健康威胁。NIH作为 它是生物医学研究的全球领导者，是世卫组织在推进知识方面的重要合作伙伴， 基础和开发新的药物干预措施。 这项建议旨在加强两个机构之间的合作， 研究的相关性、效率和范围，以支持最紧迫的公共卫生 需求 这将通过结合两个组织独特的创新办法来实现， 建立在国家卫生研究院在医学和生物医学研究方面的卓越成就及其获得大量 研究基础设施，以及世卫组织的全球影响力、其规范作用和在 与实施科学的关系。 这项合作将利用世卫组织广泛的研究计划经验， 有能力召开会议和制定议程，并通过透明和 包容性协商进程，考虑到所有相关区域和社区， 并评估世卫组织的权力下放结构。先前的研究已经证明了 这种方法。 具体目标是双重的，包括在新出现的问题领域采取合作行动， 公共卫生需要对基础、转化和实施研究进行投资; 和一个具体的目标，以促进从基础到翻译的虫媒病毒疾病的工作， 实施相关研究。扩大合作的空间很大 支持这两个机构的活动具有共同的目标和目的。

Abstract The World Health Organization (WHO) is the global lead agency in health matters. It fulfils a dual mandate of developing global norms and standards in health, and in providing technical assistance to member countries. More recently, WHO’s action in health emergencies has been highlighted as an important additional priority. Health research is an important component across all areas of work, and its role in research has recently been re-affirmed by the World Health Assembly. To achieve its objectives related to research, WHO maintains effective collaboration with governmental and other research organizations throughout the world, as evidenced by the network of WHO Collaborating Centres. WHO addresses a research portfolio with broad complementarity to the goals of NIH specialized institutes, covering communicable and non- communicable diseases, endemic, epidemic as well as emerging health threats. NIH as global leader in biomedical research, it is a key partner for WHO in advancing the knowledge base and in the development of new medicinal interventions. This proposal aims at enhancing collaboration between the two agencies to increase relevance, efficiency and reach of the research in support of the most pressing public health needs. This will be achieved by combining unique innovative approaches of both Organizations, building on NIH’s excellence in medical and biomedical research and its access to a vast research infrastructure, and on WHO’s global reach, its normative role and excellence in relation to implementation sciences. The collaboration will make use of WHO’s broad research programme experience, its capacity to convene and set agendas, and to develop consensus through transparent and inclusive consultative processes, with consideration of all relevant regions and communities, and taking stock of WHO’s decentralized structure. Prior work has demonstrated the power of this approach. Specific aims are dual, and cover collaborative action in the area of emerging issues in public health that require investments in basic, translational and implementation research; and a specific aims to promote work on arboviral diseases from basic to translational and implementation related research. There is significant room for expansion of collaborative activities in support of both institutions shared goals and objectives.