2018 Metals in Medicine Gordon Research Conference

2018 年戈登医学金属研究会议

• 批准号: 9540972
• 负责人: Edith C Glazer
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-24 至 2019-03-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9540972
• 关键词: 90Y; Academia; Ache; Address; Area; Basic Science; Bioinorganic Chemistry; Biotechnology; Carbon; Career Mobility; Case Study; Cell physiology; Cells; Characteristics; Chemicals; Chemistry; Cisplatin; Clinic; Clinical; Clinical Trials; Communities; Contrast Media; Development; Diagnosis; Diagnostic; Disease; Elements; Ensure; Entrepreneurship; Etiology; Funding; Goals; Government; Health; Homeostasis; Hour; Human; Image; Industry; Infection; Inorganic Chemistry; International; Ions; Knowledge; Learning; Magnetic Resonance Imaging; Malignant Neoplasms; Medical; Medicine; Metals; Mission; Nanotechnology; Nerve Degeneration; New Agents; Occupations; Organism; Participant; Pathologic; Pharmaceutical Preparations; Pharmacologic Substance; Play; Property; Radiopharmaceuticals; Research; Research Personnel; Role; Scientist; Seasons; System; Techniques; Technology; Therapeutic; Therapeutic Agents; Trace metal; Transition Elements; Translating; Translational Research; Translations; United States National Institutes of Health; Woman; Work; base; bench to bedside; biological systems; career; career life balance; clinical application; clinical implementation; collaborative environment; design; experience; feeding; human disease; imaging agent; improved; innovation; interest; meetings; metal complex; multidisciplinary; nanomaterials; nanoscale; new technology; novel; posters; preclinical evaluation; prevent; programs; research clinical testing; symposium; translational impact

Project Summary/Abstract The mission of the Metals in Medicine Gordon Research Conference (GRC) is to cultivate a community of multidisciplinary scientists focused on improving human health by translating basic science discoveries in the areas of bioinorganic chemistry, materials, and inorganic nanotechnology to medical application. The 2018 Metals in Medicine GRC will bring together more than 130 scientists and clinicians from around the world in academia, industry and government to discuss the latest developments in the field in the intimate and informal environment of a GRC. The organizers have three specific aims: 1) Showcase how the properties intrinsic to metals and inorganic materials can be leveraged to develop transformative new chemical and nano-scale entities for use in the diagnosis, imaging, and treatment of disease; 2) Highlight the development of new systems and optimization of existing technologies to aid in understanding the roles of metals in the pathological basis for disease and medical treatments; 3) Provide a stimulating and dynamic gathering to engage and inspire young scientists in this evolving field. The theme of the 2018 meeting is “The Indispensable Role of Metals in Medical Diagnostics, Therapeutics, and Beyond.” Aim 1 is addressed by emphasizing the unique features of metals to support human health. The opening session From Chemistry to Clinic will present successful translation of basic science discoveries to clinical implementation. This will be followed by a panel discussion by participants from industry and biotech about strategies to bridge “bench to bedside”. Other sessions mix basic science with advanced pre-clinical and clinical evaluation, with Recent Advances in Metallodrugs, Inorganic Nanomaterials in Medicine, New Agents for Imaging Applications, and Case Studies in Translational Research. Aim 2 is achieved with sessions focusing on basic research and early development of new technologies. The role of specific metals in the etiology of disease will be presented in the session Metal Homeostasis in Health and Disease, and the emerging area of metal-bioligand speciation in Metalloglycomics, while Analytical Techniques for Metals in Biological Systems presents approaches and technologies to detect, quantify, and trace metals and inorganic materials. The Emerging Investigators session will complete the program, and supports Aim 3, with an emphasis on encourage early career investigators. Speakers will also be selected from the submitted abstracts, acheiving 25% representation from early stage scientists and ensuring that the most exciting new discoveries are presented. Other program features focused include “Poster Slams”, the “Power Hour” to address issues around career advancement for STEM women scientists, and many informal activities including discussion tables to address topics such as “Entrepreneurship,” “Translation,” “Work Life Balance,” and “Navigating Job Searches”.

项目概要/摘要 戈登医学金属研究会议 (GRC) 的使命是培养一个社区 多学科科学家致力于通过将基础科学发现转化为人类健康来改善人类健康 生物无机化学、材料和无机纳米技术的医学应用领域。 2018年 Metals in Medicine GRC 将汇聚来自世界各地的 130 多名科学家和临床医生 学术界、工业界和政府以亲密和非正式的方式讨论该领域的最新发展 GRC 的环境。组织者有三个具体目标： 1) 展示固有属性如何 可以利用金属和无机材料来开发变革性的新化学和纳米级材料 用于疾病诊断、成像和治疗的实体； 2）突出新发展 系统和现有技术的优化，以帮助了解金属在病理中的作用 疾病和医学治疗的依据； 3) 提供一个刺激且充满活力的聚会，以吸引和参与 激励这个不断发展的领域的年轻科学家。 2018年会议的主题是“金属在医学诊断、治疗、 以及超越”。目标 1 通过强调金属支持人类健康的独特特性来实现。的 开幕会议从化学到临床将展示基础科学发现的成功转化 临床实施。随后将由来自工业和生物技术的参与者进行小组讨论 关于桥接“工作台到床边”的策略。其他课程将基础科学与先进的临床前研究相结合 和临床评估，金属药物的最新进展，医学中的无机纳米材料，新 成像应用代理和转化研究案例研究。目标 2 通过会议实现 注重基础研究和新技术的早期开发。特定金属的作用 疾病的病因学将在健康与疾病中的金属稳态会议中介绍，以及 金属化学中金属生物配体形态形成的新兴领域，而金属分析技术 生物系统提出了检测、量化和追踪金属和无机物的方法和技术 材料。新兴研究者会议将完成该计划，并支持目标 3， 强调鼓励早期职业调查员。演讲者也将从提交的材料中选出 摘要，使早期科学家的代表性达到 25%，并确保最令人兴奋的新成果 提出了发现。其他重点项目特色包括“海报大满贯”、“Power Hour” 解决 STEM 女科学家的职业发展问题，以及许多非正式活动，包括 讨论“创业”、“翻译”、“工作与生活平衡”等主题 “导航求职”。