2018 Metals in Medicine Gordon Research Conference

项目总结/摘要 戈登医学研究会议（GRC）的使命是培养一个 多学科科学家致力于通过将基础科学发现转化为 从生物无机化学、材料、无机纳米技术到医学应用。2018年 医学中的金属GRC将汇集来自世界各地的130多名科学家和临床医生， 学术界，工业界和政府讨论在该领域的最新发展，在亲密和非正式的 一个GRC的环境组织者有三个具体目标：1）展示如何固有的属性， 金属和无机材料可以被用来开发变革性的新化学和纳米尺度 实体用于疾病的诊断、成像和治疗; 2）突出新的 系统和现有技术的优化，以帮助理解金属在病理学中的作用， 疾病和医疗的基础; 3）提供一个刺激和动态的聚会， 在这个不断发展的领域激励年轻科学家。 2018年会议的主题是“金属在医疗诊断，治疗， 超越”。目标1通过强调金属的独特特性来支持人类健康。的 开幕式从化学到临床将介绍基础科学发现的成功翻译， 临床实施。随后将由来自工业和生物技术的参与者进行小组讨论 关于“从长凳到床边”的桥梁策略。其他会议混合基础科学与先进的临床前 和临床评价，与金属药物的最新进展，无机纳米材料在医学，新 成像应用的代理商和转化研究的案例研究。目标2通过会话实现 注重基础研究和新技术的早期开发。特定金属在 疾病的病因学将在健康与疾病的金属稳态会议中提出， 金属糖组学中的金属生物配体形态形成的新兴领域， 生物系统提出的方法和技术，以检测，量化，并跟踪金属和无机 材料.新兴研究者会议将完成该计划，并支持目标3， 强调鼓励早期职业调查员。发言人也将从提交的 摘要，达到25%的代表性，从早期阶段的科学家，并确保最令人兴奋的新 的发现提出。其他节目特色包括“海报大满贯”，“电力小时”， 解决围绕STEM女科学家职业发展的问题，以及许多非正式活动，包括 讨论表，以解决“创业”，“翻译”，“工作生活平衡”等主题， “导航作业”。

Project Summary/Abstract The mission of the Metals in Medicine Gordon Research Conference (GRC) is to cultivate a community of multidisciplinary scientists focused on improving human health by translating basic science discoveries in the areas of bioinorganic chemistry, materials, and inorganic nanotechnology to medical application. The 2018 Metals in Medicine GRC will bring together more than 130 scientists and clinicians from around the world in academia, industry and government to discuss the latest developments in the field in the intimate and informal environment of a GRC. The organizers have three specific aims: 1) Showcase how the properties intrinsic to metals and inorganic materials can be leveraged to develop transformative new chemical and nano-scale entities for use in the diagnosis, imaging, and treatment of disease; 2) Highlight the development of new systems and optimization of existing technologies to aid in understanding the roles of metals in the pathological basis for disease and medical treatments; 3) Provide a stimulating and dynamic gathering to engage and inspire young scientists in this evolving field. The theme of the 2018 meeting is “The Indispensable Role of Metals in Medical Diagnostics, Therapeutics, and Beyond.” Aim 1 is addressed by emphasizing the unique features of metals to support human health. The opening session From Chemistry to Clinic will present successful translation of basic science discoveries to clinical implementation. This will be followed by a panel discussion by participants from industry and biotech about strategies to bridge “bench to bedside”. Other sessions mix basic science with advanced pre-clinical and clinical evaluation, with Recent Advances in Metallodrugs, Inorganic Nanomaterials in Medicine, New Agents for Imaging Applications, and Case Studies in Translational Research. Aim 2 is achieved with sessions focusing on basic research and early development of new technologies. The role of specific metals in the etiology of disease will be presented in the session Metal Homeostasis in Health and Disease, and the emerging area of metal-bioligand speciation in Metalloglycomics, while Analytical Techniques for Metals in Biological Systems presents approaches and technologies to detect, quantify, and trace metals and inorganic materials. The Emerging Investigators session will complete the program, and supports Aim 3, with an emphasis on encourage early career investigators. Speakers will also be selected from the submitted abstracts, acheiving 25% representation from early stage scientists and ensuring that the most exciting new discoveries are presented. Other program features focused include “Poster Slams”, the “Power Hour” to address issues around career advancement for STEM women scientists, and many informal activities including discussion tables to address topics such as “Entrepreneurship,” “Translation,” “Work Life Balance,” and “Navigating Job Searches”.