2022 Metals in Medicine Gordon Research Conference

2022 年戈登医学金属研究会议

• 批准号: 10469045
• 负责人: Edith C Glazer
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10469045
• 关键词: Academia; Address; Area; Basic Science; Bioinorganic Chemistry; Career Mobility; Catalysis; Cells; Chemicals; Chemistry; Clinical; Communities; Complex; Contrast Media; Data; Developing Countries; Development; Diagnosis; Diagnostic; Disease; Early Diagnosis; Ensure; Environment; Etiology; Fertilization; Fostering; Funding; Government; Growth; Health; Hour; Human; Image; Industry; International; Learning; Magnetic Resonance Imaging; Medical; Medicine; Mentors; Metals; Methods; Mission; Modernization; Molecular; Nanotechnology; Oral; Participant; Pathologic; Pharmaceutical Preparations; Positron-Emission Tomography; Postdoctoral Fellow; Process; Property; Proteins; Radioisotopes; Radionuclide therapy; Research; Research Personnel; Role; Science; Scientist; Social Interaction; Stimulus; System; Technology; Therapeutic; Therapeutic Agents; Trace metal; Translating; Translations; United States National Institutes of Health; Visit; Woman; Work; base; career; catalyst; chelation; clinical translation; design; disease diagnosis; experience; graduate student; improved; informal atmosphere; innovation; meetings; metal complex; multidisciplinary; nanomaterials; nanoscale; nanoscience; nanotheranostics; new technology; next generation; novel; personalized medicine; posters; preclinical evaluation; programs; research clinical testing; small molecule; symposium; theranostics; tool

PROJECT SUMMARY/ABSTRACT The mission of the Metals in Medicine Gordon Research Conference (GRC) is to cultivate a community of multidisciplinary scientists focused on improving human health by translating basic science discoveries in the areas of bioinorganic chemistry, materials, and inorganic nanotechnology to medical application. The 2022 Metals in Medicine GRC will bring together more than 150 scientists and clinicians from around the world in academia, industry and government to discuss the latest developments in the field in the intimate and informal environment of a GRC. The organizers have three specific aims: 1) Showcase how the properties intrinsic to metals and inorganic materials can be leveraged to develop transformative new chemical and nano-scale entities for use in the diagnosis, imaging, and treatment of disease; 2) Highlight the development of new systems and optimization of existing technologies to aid in understanding the roles of metals in the pathological basis for disease and medical treatments; 3) Provide a stimulating and dynamic gathering to engage and inspire young scientists in this evolving field. The theme of the 2022 meeting is “Advancing the use of metal-based compounds and nanotheranostics for personalized medicine.” Aim 1 is addressed by emphasizing the unique features of metals to support human health. Several sessions mix basic science with advanced pre-clinical and clinical evaluation. The program opens with Supramolecular Coordination Complexes for Biomedical Applications, which will feature the latest innovations in nanoscience as it relates to self-assembling molecular systems and nanomaterials as theranostics. Novel Chelation Strategies and Applications for Radionuclides and Contrast Agents focuses on stably complexing metals to bioconjugates for diagnostics (PET and MRI), and for targeted radionuclide therapy. There will be two sessions on metal-based therapeutics (Stimuli-responsive Materials for Therapy and Imaging and Targeted Metal-based Therapeutics). Clinical Advances for Metals in Medicine will discuss metal-based diagnostics and therapeutics that are in early human trials. Aim 2 is achieved with sessions focusing on basic research and early development of new technologies. The role of specific metals in the etiology of disease will be presented in the session Essential Metals in Disease Mechanisms, and the emerging area of Catalysis in Cells highlights advances in this traditional application of metals in an untraditional environment. Novel Metallomics Methods and Tools presents approaches and technologies to detect, quantify, and trace metals and inorganic materials. The Early Career Investigators/Emerging Topics session will complete the program, and supports Aim 3, with an emphasis on encourage early career investigators. Speakers will also be selected from the submitted abstracts, achieving 25% representation from early stage scientists and ensuring that the most exciting new discoveries are presented. Other program features focused include “Poster Previews”, the “Power Hour” to address issues around career advancement for STEM women scientists, and many informal activities.

项目摘要/摘要 戈登医学金属研究会议(GRC)的使命是培养一个社区 多学科科学家致力于通过将基础科学发现转化为 生物无机化学、材料和无机纳米技术领域的医学应用。2022年 金属医学GRC将汇集来自世界各地的150多名科学家和临床医生 学术界、产业界和政府在私下和非正式地讨论该领域的最新发展 GRC的环境。组织者有三个具体目标：1)展示属性如何内在地 金属和无机材料可以被用来开发具有变革性的新的化学和纳米级实体 用于疾病的诊断、成像和治疗；2)突出新系统和 优化现有技术以帮助理解金属在糖尿病的病理基础中的作用 疾病和医疗；3)提供刺激和活力的聚会，以吸引和激励年轻人 这一不断发展的领域的科学家。 2022年会议的主题是“推进金属基化合物和纳米变色剂的使用 个性化的医疗服务。目标1通过强调金属的独特特性来支持人类 健康。有几次会议将基础科学与高级临床前和临床评估结合起来。程序将打开 具有生物医学应用的超分子配位络合物，这将是最新的 纳米科学中的创新，因为它涉及自组装分子系统和纳米材料 神学。放射性核素和造影剂的新型螯合策略和应用 稳定地将金属络合成生物结合物，用于诊断(PET和MRI)和靶向放射性核素治疗。 将有两个关于基于金属的治疗(治疗和成像的刺激反应材料)的会议 和靶向金属治疗)。金属在医学上的临床进展将讨论金属基 处于早期人体试验中的诊断和治疗。目标2是通过侧重于基础知识的课程来实现的 研究和早期开发新技术。特定金属在疾病病因学中的作用 将在疾病机制中的必需金属和新兴催化领域会议上发表 CELS强调了金属在非传统环境中的这一传统应用方面的进展。小说 金属组学方法和工具提供了检测、量化和跟踪金属和 无机材料。早期职业调查/新兴话题课程将完成该项目，以及 支持AIM 3，重点是鼓励早期职业调查人员。演讲者也将从以下选项中选出 提交的摘要，从早期科学家那里获得25%的代表性，并确保大多数 令人振奋的新发现被提出。其他重点关注的节目功能包括“海报预览”、“力量” 一小时“，以解决与STEM女科学家的职业发展有关的问题，以及许多非正式活动。