(1/2) Ponce Health Sciences University-Moffitt Cancer Center Partnership

(1/2) 庞塞健康科学大学-莫菲特癌症中心合作伙伴关系

• 批准号: 9569588
• 负责人: Julie Dutil
• 金额: $ 161.94万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-25 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9569588
• 关键词: Accreditation; Achievement; Address; Award; Basic Science; Behavior; Bioinformatics; Bone Marrow Transplantation; Cancer Center; Clinical; Clinical Data; Clinical Research; Collaborations; Collection; Colorectal Cancer; Communication; Communities; Community Outreach; Data; Data Analyses; Databases; Development; Education; Educational Activities; Educational Materials; Educational process of instructing; Ensure; Epidemiology; Faculty; Fellowship; Florida; Funding; Genotype; Goals; Grant; Grant Review; Growth; Health Sciences; Hematology; Hispanics; Hospitals; Institution; Intervention Trial; Island; Joints; Latino; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of ovary; Manuscripts; Medical Students; Molecular Analysis; Mutation; Network Infrastructure; Normal tissue morphology; Operative Surgical Procedures; Outcome; Outreach Research; Participant; Patient Recruitments; Patients; Peer Review; Peer Review Grants; Play; Population Research; Protocols documentation; Publishing; Puerto Rico; Research; Research Infrastructure; Research Personnel; Residencies; Resources; Role; Rotation; Science; Stem cell transplant; Structure; Students; Surgical Oncology; Talents; Technology; Tissue Banks; Training; Training and Education; Translational Research; Tumor Tissue; Underrepresented Groups; Underrepresented Populations; Underserved Population; Universities; Vision; anticancer research; biobank; cancer care; cancer education; cancer health disparity; cancer prevention; career development; cohesion; education research; epidemiology study; expectation; graduate student; improved; malignant breast neoplasm; medical schools; oncology; outreach; outreach program; precision medicine; precision oncology; programs; recruit; sample collection; screening; success; sun protection; tool; tumor

The Ponce Health Sciences University (PHSU) and the Moffitt Cancer Center (MCC) have forged a strong working relationship founded on seamless communication with mutual support and benefits. With Partnership resources and significant commitment from both institutions, we have established joint programs enhancing basic and clinical research, enriching cancer outreach, expanding cancer education, and creating a unique Hispanic/Latino (H/L) Biobank, leading to the development of a robust network and infrastructure necessary for a sustained long-term collaboration to improve cancer outcomes in the H/L population. The U54 Partnership's immediate impact includes the identification of new mutations in breast and lung cancer in H/L patients, recruitment of new faculty essential for sustainability and growth, and 84 community outreach educational activities for H/Ls in Florida (FL) and Puerto Rico (PR). The development of the Puerto Rico Biobank (PRBB) and the training of clinical researchers, with 25 clinical intervention trials activated in Ponce, demonstrate the broad impact realized through the Partnership. Furthermore the Partnership had a critical role in the ACGME re-accreditation of the Hematology/Oncology Fellowship in PR, in the establishment of two stem cell transplant programs in PR by fellows trained in the MCC Bone Marrow Transplant unit, and in the establishment of an ACGME-accredited surgical residency in Ponce with surgical oncology rotations at MCC. The short-term metrics of the first 4 years of the U54 Partnership grant include 48 student participants, 35 peer-reviewed manuscripts published, and 29 grants funded out of a total of 64 submitted. Our vision for the U54 PACHE renewal is to further grow and engage faculty and students in cancer precision medicine research that directly impacts the H/L populations in FL and PR. The Partnership has the requisite components to fully execute precision medicine in an underserved population—a biobank, quantitative science core (QSC) to analyze data, culturally sensitive outreach materials, expertise in the latest technologies, and a robust research portfolio. The four specific aims for the U54 Partnership renewal are the following. Aim 1: To increase the number of researchers at PHSU focused on basic/translational research in cancer and to augment the number of researchers in cancer health disparities at MCC. This is facilitated with joint projects in ovarian and breast cancer. Aim 2: To further develop outreach programs and research efforts in the H/L communities at both PHSU and MCC. An epidemiological project will examine the impact of receipt of MC1R genotypes on personal sun protection behaviors. Aim 3: To increase support for basic, translational and clinical research in the H/L population by establishing the QSC and further developing the PRBB. The MCC Total Cancer Care protocol will be developed in Ponce hospitals and leveraged by the PRBB to facilitate tissue collection. Aim 4: To provide comprehensive and structured student research education at both PHSU and MCC to facilitate the expansion and success of cancer researchers and clinicians in the H/L population.

庞塞健康科学大学（PHSU）和莫菲特癌症中心（MCC）已经建立了一个强大的