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2/2 Ponce Health Sciences University-Moffitt Cancer Center Partnership

2/2 庞塞健康科学大学-莫菲特癌症中心合作伙伴关系

基本信息

批准号：
10762077
负责人：
Julie Dutil
金额：
$ 141.45万
依托单位：
H. LEE MOFFITT CANCER CTR & RES INST
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-24 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10762077
关键词：
Accreditation Achievement Address Admixture Advocate Affect Basic Cancer Research Basic Science Bay Region Biological COVID-19 pandemic Cancer Center Cancer Patient Caregivers Clinical Clinical Research Collaborations Communication Communities Community Developments Community Health Community Health Education Community Outreach Complex Comprehensive Cancer Center Development Direct Costs Doctor of Philosophy Earthquakes Education Educational Materials Ensure Environment Evaluation Evaluation Research Evolution Faculty Florida Fostering Funding Genetic Genomics Goals Grant Growth Health Health Disparities Research Health Educators Health Sciences Health Services Accessibility Hematology Hispanic Hurricane Infrastructure Institution Intervention Joints Language Latino Latino Population Learning Malignant Neoplasms Medical Medical Students Minority Participation NCI-Designated Cancer Center Natural Disasters Oncology Operative Surgical Procedures Outcome Peer Review Population Postdoctoral Fellow Poverty Preparation Process Productivity Psychological Factors Publications Puerto Rico Reduce health disparities Research Research Personnel Research Project Grants Research Support Residencies Resources Science Specimen Tissue Microarray Training Universities anticancer research biobank cancer clinical trial cancer education cancer health disparity career catalyst community engagement disparity gap doctoral student empowerment experience forging genomic data graduate medical education health disparity improved innovation inter-institutional novel outreach outreach program programs recruit resilience social factors social media translational cancer research undergraduate student

项目摘要

ABSTRACT | OVERALL The Hispanic/Latino (H/L) communities in the Ponce and Tampa Bay regions experience both shared and unique challenges associated with poverty, access to care, and language. The Ponce Health Sciences University (PHSU) in Puerto Rico (PR) and the Moffitt Cancer Center (MCC) in Florida have forged a strong relationship and leveraged their respective strengths and resources to address these needs with the ultimate goal of eliminating cancer health disparities. The 15-year Partnership has established joint programs for basic and clinical research, cancer outreach, cancer education, and training, and biobanking, building networks of investigators focused on cancer disparities and infrastructure for sustained long-term collaboration. Combined with the establishment and growth of a unique biobanking resource for H/L and the integration of quantitative sciences expertise, this dynamic environment is a catalyst for the recruitment of new faculty at PHSU in basic and translational cancer research, increases the health disparities research focus at MCC and stimulates innovative cancer research. To ensure a durable impact, the Partnership fosters the development of cancer researchers and clinicians through an exchange of research and medical trainees between institutions and supporting the successful advancement of Early-Stage Investigators (ESIs). The Partnership and our outreach activities continue to be integral in promoting cancer health in our H/L communities and has provided vital support for overcoming two major hurricanes, devastating earthquakes, and the COVID pandemic. The challenges, achievements, and lessons learned to provide a strong basis to guide the evolution and further expansion of this Partnership, whose primary goals are to reduce cancer disparities in the Hispanic/Latino (H/L) communities and to contribute to the elimination of health disparities in the population at large. The specific aims for the U54 Partnership renewal are (1) Increase Partnership investigators and collaborations committed to innovative cancer health disparities research, creating long-term sustainability. This will be accomplished through the engagement of faculty and ESIs with resources to support collaborations, grant preparations, publications, and networking. (2) Identify and foster the growth of diverse trainees for a career in cancer research and health disparities. We will support the recruitment and development of trainees from diverse backgrounds across the career continuum with an emphasis on H/L. (3) Support novel research projects that will contribute to the identification and elimination of cancer health disparities in H/L. We will foster the development of projects that investigate the biological basis, psychological and social factors of cancer disparities through a rigorous evaluation of research projects that have the potential to reduce specific disparity gaps. (4) Increase community engagement in cancer health disparities research. This will be accomplished by fostering community engagement, including bi-directional activities, education, increased social media presence, and dialogue with the research component and activities of our Community Health Educator.

摘要|整体庞塞和坦帕湾地区的西班牙裔/拉丁裔（H/L）社区既有共同的经验，也有独特的经验。与贫困、获得护理和语言相关的挑战。庞塞健康科学大学（PHSU）在波多黎各（PR）和莫菲特癌症中心（MCC）在佛罗里达已经建立了牢固的关系并利用各自的优势和资源来满足这些需求，最终目标是消除癌症健康差距。这个为期15年的伙伴关系建立了基本和临床研究、癌症外展、癌症教育和培训以及生物库，建立研究人员重点关注癌症差异和持续长期合作的基础设施。组合随着H/L独特的生物库资源的建立和发展，以及定量科学专业知识，这种动态的环境是在PHSU招聘新教师的催化剂，和转化癌症研究，增加了MCC的健康差异研究重点，并刺激创新的癌症研究为了确保持久的影响，该伙伴关系促进癌症的发展，研究人员和临床医生，通过机构之间的研究和医学实习生交流，支持早期研究者（ESI）的成功发展。伙伴关系和我们的外联活动活动仍然是促进我们H/L社区癌症健康的组成部分，并提供了重要的支持克服了两次大飓风、毁灭性地震和新冠疫情。挑战，取得的成就和吸取的经验教训，以提供强有力的基础，指导发展和进一步扩大伙伴关系，其主要目标是减少西班牙裔/拉丁裔（H/L）社区的癌症差异，为消除广大民众的健康差距做出贡献。U 54的具体目标伙伴关系的更新是（1）增加致力于创新的伙伴关系调查和合作癌症健康差异研究，创造长期可持续性。这将通过以下方式实现：教师和esi的资源，以支持合作，赠款准备，出版物，联网(2)识别和促进不同的学员在癌症研究和健康事业的发展差距。我们将支持招聘和发展来自不同背景的学员，职业连续性，重点是H/L。(3)支持新的研究项目，这将有助于确定和消除H/L中的癌症健康差异。我们将促进项目的发展通过一个严格的调查癌症差异的生物学基础，心理和社会因素，评估有可能缩小具体差距的研究项目。(4)增加社区参与癌症健康差异研究。这将通过促进社区参与，包括双向活动，教育，增加社交媒体的存在，以及与我们的社区健康教育者的研究组成部分和活动。

项目成果

期刊论文数量（24）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Early2 factor (E2F) deregulation is a prognostic and predictive biomarker in lung adenocarcinoma.

DOI：
10.18632/oncotarget.12672
发表时间：
2016-12-13
期刊：
Oncotarget
影响因子：
0
作者：
Chen L;Kurtyka CA;Welsh EA;Rivera JI;Engel BE;Muñoz-Antonia T;Yoder SJ;Eschrich SA;Creelan BC;Chiappori AA;Gray JE;Ramirez JL;Rosell R;Schabath MB;Haura EB;Chen DT;Cress WD
通讯作者：
Cress WD

The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.