Maternal-Fetal Medicine Units Network -- The Northwestern Study Center

 描述（由申请人提供）：在美国，每年约有400万例分娩，分娩是住院的主要指征。相应地，预防不良产科结局，包括早产和孕产妇发病率，是一个重要目标，旨在改善产科结局的临床试验和观察性研究至关重要。母胎医学单位网络通过建立多机构研究基础设施，是有效实现这一目标的重要机制。西北研究中心，通过其创新的招聘技术和研究设计方法的使用，自2001年以来一直是MFMU网络的富有成效的成员，并由两个机构组成，它们在MFMU网络中合作了10多年：西北大学和北岸大学卫生系统。此外，该机构的两个母胎医学部门在多个其他临床研究和试验方面进行了长期持续的合作。在这项提案中，我们提出了西北研究中心的申请，以恢复其在MFMU网络的参与。由经验丰富的临床研究人员团队（William Grobman，医学博士，MBA; Alan Gobeman，医学博士; Mara Dinsmoor，医学博士，公共卫生硕士; Gail Mallett，RN）领导，西北研究中心将继续为MFMU网络的目标做出重大贡献，通过社会经济多样化患者的强大招募以及新颖研究的概念和发展。

 DESCRIPTION (provided by applicant): In the United States, there are approximately 4 million births per year and childbirth is the leading indication for hospitalization. Correspondingly, the prevention of adverse obstetric outcomes, including preterm birth and maternal morbidity, is an important goal, and clinical trials and observational studies designed to improve obstetric outcomes are of the utmost importance. The Maternal-Fetal Medicine Units (MFMU) Network, by creating a multi-institutional research infrastructure, is an important mechanism to accomplish this goal effectively. The Northwestern Study Center, through its use of innovative recruitment techniques and study design approaches, has been a productive member of the MFMU Network since 2001, and is composed of two institutions that have worked together in the MFMU Network for over 10 years: Northwestern University and NorthShore University Health System. The two Maternal-Fetal Medicine Divisions of the institutions, in addition, have a long and continuing collaboration on multiple other clinical research studies and trials. In this proposal, we present the application of the Northwestern Study Center to renew its participation in the MFMU Network. Led by a team of experienced clinical researchers (William Grobman, MD, MBA; Alan Peaceman, MD; Mara Dinsmoor, MD, MPH; Gail Mallett, RN), the Northwestern Study Center will continue its significant contributions to the MFMU Network's goals though robust enrollment of socioeconomically diverse patients and the conception and development of novel studies.