Maternal-Fetal Medicine Units Network -- The Northwestern Study Center

母胎医学单位网络——西北研究中心

• 批准号: 9929278
• 负责人: William Adam Grobman
• 金额: $ 13.21万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9929278
• 关键词: Admission activity; Affect; Birth; Cardiovascular Diseases; Child; Childbirth; Clinical; Clinical Research; Clinical Trials; Collaborations; Collection; Conceptions; Data; Data Coordinating Center; Data Quality; Development; Discipline of obstetrics; Enrollment; Goals; Health Care Costs; Health system; Hospitalization; Institution; Maternal-Fetal Medicine Units Network; Maternal-fetal medicine; Morbidity - disease rate; National Institute of Child Health and Human Development; Observational Study; Outcome; Pathology; Patients; Population; Pregnancy; Pregnant Women; Premature Birth; Prevention; Prevention strategy; Procedures; Process; Protocols documentation; Provider; Public Health; Research Design; Research Infrastructure; Research Personnel; Study Subject; Techniques; United States; Universities; Woman; Women' s Health; Work; adverse outcome; care outcomes; experience; high risk; improved; innovation; maternal morbidity; member; novel; offspring; organizational structure; participant retention; recruit; research study; retention rate; socioeconomics; treatment strategy

Abstract In the United States, there are approximately 4 million births per year and childbirth is the leading indication for hospitalization. Correspondingly, the prevention of adverse obstetric outcomes, including preterm birth and maternal morbidity, is an important goal, and clinical trials and observational studies designed to improve obstetric outcomes are of the utmost importance. The Maternal-Fetal Medicine Units (MFMU) Network, by creating a multi-institutional research infrastructure, is an important mechanism to accomplish this goal effectively. The Northwestern Study Center, through its use of innovative recruitment techniques and study design approaches, has been a productive member of the MFMU Network since 2001, and is composed of two institutions that have worked together in the MFMU Network for over 10 years: Northwestern University and NorthShore University Health System. The two Maternal-Fetal Medicine Divisions of the institutions, in addition, have a long and continuing collaboration on multiple other clinical research studies and trials. In this proposal, we present the application of the Northwestern Study Center to renew its participation in the MFMU Network. Led by a team of experienced clinical researchers (William Grobman, MD, MBA; Alan Peaceman, MD; Mara Dinsmoor, MD, MPH; Gail Mallett, RN), the Northwestern Study Center will continue its significant contributions to the MFMU Network’s goals though robust enrollment of socioeconomically diverse patients and the conception and development of novel studies.

摘要 在美国，每年大约有400万例分娩，分娩是新生儿的主要指征。 住院相应地，预防不良的产科结果，包括早产， 产妇发病率，是一个重要的目标，临床试验和观察性研究，旨在改善 产科结果至关重要。母胎医学单位（MFMU）网络，由 建立多机构研究基础设施是实现这一目标的重要机制 有效地西北研究中心，通过其创新的招聘技术和研究的使用 设计方法，自2001年以来一直是MFMU网络的生产成员，由两个 在MFMU网络中合作超过10年的机构：西北大学和 北岸大学卫生系统。各机构的两个母胎医学部， 此外，在多个其他临床研究和试验方面也有长期和持续的合作。在这 建议，我们提出申请西北研究中心，以恢复其参与MFMU 网络在一组经验丰富的临床研究人员的带领下（William Grobman，MD，MBA; Alan Gobeman， MD; Mara Dinsmoor，MD，MPH; Gail Mallett，RN），西北研究中心将继续其重要的 通过大量招募社会经济多样化的患者，为MFMU网络的目标做出贡献 小说研究的概念和发展。