Why Does Heart Rate Variability Matter for Emotion Regulation
为什么心率变异对情绪调节很重要
基本信息
- 批准号:9905327
- 负责人:
- 金额:$ 42.51万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-04-15 至 2022-03-31
- 项目状态:已结题
- 来源:
- 关键词:AffectAgingAllelesAlzheimer&aposs DiseaseAlzheimer&aposs disease riskAmygdaloid structureBlood PressureBlood flowBrainBrain regionBreathingCardiovascular systemCharacteristicsDepressed moodDown-RegulationElderlyEmotionalEmotionsFeedbackFrequenciesFunctional disorderGeneticHeadHealthHeartHeart RateHomeostasisIndividual DifferencesLateralLeadMeasuresMedialMediatingMeditationMonitorOperating SystemOutcomeOutcome MeasureParticipantPatient Self-ReportPersonal SatisfactionPhysiologicalPhysiologyPrefrontal CortexPressoreceptorsProcessProtocols documentationRelaxationRestRiskRoleSignal TransductionSpeedStructureSystemTestingUp-RegulationWell in selfage differenceanxiousapolipoprotein E-4emotion regulationemotional experienceexperienceflexibilitygenetic risk factorheart rate variabilityimprovedindexingneurovascularoscillatory blood flowpre-clinicalresponseyoung adult
项目摘要
ABSTRACT
Having a heart with a steady beat is not optimal. The brain sends signals about various body states including
blood pressure and breathing that contribute oscillatory rhythms to the speed of heartbeats and increase heart
rate variability (HRV). For reasons that are not yet clear, having greater HRV at rest is associated with better
emotion regulation and well-being. People with higher HRV tend to be less anxious, less depressed, less
hostile and produce more context-appropriate emotional responses. One potential explanation for the
relationship between HRV and emotion regulation is that the same set of brain regions regulates autonomic
states and emotions, and so both HRV and emotion regulation reflect the general health and efficacy of this
central autonomic network in the brain. However, it appears that the influences do not just flow from the brain
to the heart. Paced breathing at the resonance frequency of the heart rate-baroreceptor feedback loop (around
6 breaths/min, a pace often attained during meditative practice) stimulates resonance characteristics of the
cardiovascular system and so increases total HRV amplitude dramatically. Recent studies using this approach
have shown that increasing HRV during short daily sessions can improve longer-term emotional outcomes. But
it is unclear why episodes of high HRV have a positive impact. This project would be the first to examine the
brain mechanisms of these effects, testing the hypothesis that episodes of high HRV induced by resonance
frequency breathing lead to positive outcomes because they induce dynamic blood flow oscillations in brain
regions that monitor and regulate physiological body states. Our experimental manipulation will be a 5-week
protocol with random assignment to either a daily session with paced breathing at resonance frequency or one
of two control conditions. We test the hypothesis that resonance frequency breathing will enhance measures of
emotional well-being, resting state functional connectivity among brain regions involved in emotion regulation,
and flexible up- and down-regulation of the amygdala during emotional experience. Furthermore, we test the
hypothesis that these outcomes will be mediated by blood flow variability during paced breathing rather than by
alternative mechanisms. The expected findings would indicate that HRV is more than just an indicator of
health, with an active role in stimulating brain regions in the central autonomic network to improve their
coordination and function.
摘要
拥有一颗稳定跳动的心脏并不是最佳选择。大脑发出各种身体状态的信号,
血压和呼吸,有助于振荡节奏的心跳速度,并增加心脏
心率变异性(HRV)。由于尚不清楚的原因,静息时心率变异性越大,
情绪调节和幸福感心率变异性高的人往往不那么焦虑,不那么抑郁,
产生更适合情境的情绪反应。一个可能的解释是,
心率变异性和情绪调节之间的关系是,同一组大脑区域调节自主神经,
状态和情绪,因此HRV和情绪调节反映了整体健康状况和这种状态的功效。
中枢自主神经网络然而,这些影响似乎不仅仅来自大脑,
打到心脏在心率-压力感受器反馈回路的共振频率下进行有节奏呼吸(约
6呼吸/分钟,在冥想练习中经常达到的速度)刺激大脑的共振特征。
心血管系统,因此显著增加总HRV幅度。最近使用这种方法的研究
已经表明,在短期的日常会话中增加心率变异性可以改善长期的情绪结果。但
尚不清楚为什么高心率变异性的发作具有积极的影响。该项目将是第一个审查
这些影响的大脑机制,测试假设,高心率变异性的事件引起的共振
频率呼吸导致积极的结果,因为它们诱导大脑中的动态血流振荡
监控和调节生理身体状态的区域。我们的实验操作将是一个为期5周的
随机分配到共振频率下的起搏呼吸每日会话或
两个控制条件。我们测试的假设,共振频率呼吸将提高措施,
情绪健康,涉及情绪调节的大脑区域之间的静息状态功能连接,
以及在情绪体验中杏仁核的灵活上下调节。此外,我们还测试了
假设这些结果将由起搏呼吸期间的血流变异性介导,而不是由
替代机制。预期的结果表明,HRV不仅仅是一个指标,
健康,在刺激中央自主神经网络中的大脑区域以改善其
协调和功能。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
MARA MATHER其他文献
MARA MATHER的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('MARA MATHER', 18)}}的其他基金
Effects of Resonance-Frequency Breathing on Preclinical Alzheimer’s Disease Biomarkers and Cognition
共振频率呼吸对临床前阿尔茨海默病生物标志物和认知的影响
- 批准号:
10591329 - 财政年份:2023
- 资助金额:
$ 42.51万 - 项目类别:
Effects of Acute Stress Exposure on Plasma beta-amyloid Levels
急性应激暴露对血浆 β-淀粉样蛋白水平的影响
- 批准号:
10575514 - 财政年份:2022
- 资助金额:
$ 42.51万 - 项目类别:
Why Does Heart Rate Variability Matter for Emotion Regulation
为什么心率变异对情绪调节很重要
- 批准号:
9320174 - 财政年份:2017
- 资助金额:
$ 42.51万 - 项目类别:
Why Does Heart Rate Variability Matter for Emotion Regulation
为什么心率变异对情绪调节很重要
- 批准号:
9471784 - 财政年份:2017
- 资助金额:
$ 42.51万 - 项目类别:
Effects of estrogen on working memory during stress
雌激素对压力期间工作记忆的影响
- 批准号:
8823616 - 财政年份:2015
- 资助金额:
$ 42.51万 - 项目类别:
Effects of estrogen on working memory during stress
雌激素对压力期间工作记忆的影响
- 批准号:
8996102 - 财政年份:2015
- 资助金额:
$ 42.51万 - 项目类别:
The effects of stress on neural processing of reward and risk
压力对奖励和风险的神经处理的影响
- 批准号:
8097445 - 财政年份:2010
- 资助金额:
$ 42.51万 - 项目类别:
The effects of stress on neural processing of reward and risk
压力对奖励和风险的神经处理的影响
- 批准号:
7979728 - 财政年份:2010
- 资助金额:
$ 42.51万 - 项目类别:
The effects of stress on neural processing of reward and risk
压力对奖励和风险的神经处理的影响
- 批准号:
8485489 - 财政年份:2010
- 资助金额:
$ 42.51万 - 项目类别:
The effects of stress on neural processing of reward and risk
压力对奖励和风险的神经处理的影响
- 批准号:
8286232 - 财政年份:2010
- 资助金额:
$ 42.51万 - 项目类别:
相似海外基金
Interplay between Aging and Tubulin Posttranslational Modifications
衰老与微管蛋白翻译后修饰之间的相互作用
- 批准号:
24K18114 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
The Canadian Brain Health and Cognitive Impairment in Aging Knowledge Mobilization Hub: Sharing Stories of Research
加拿大大脑健康和老龄化认知障碍知识动员中心:分享研究故事
- 批准号:
498288 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Operating Grants
EMNANDI: Advanced Characterisation and Aging of Compostable Bioplastics for Automotive Applications
EMNANDI:汽车应用可堆肥生物塑料的高级表征和老化
- 批准号:
10089306 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Collaborative R&D
Baycrest Academy for Research and Education Summer Program in Aging (SPA): Strengthening research competencies, cultivating empathy, building interprofessional networks and skills, and fostering innovation among the next generation of healthcare workers t
Baycrest Academy for Research and Education Summer Program in Aging (SPA):加强研究能力,培养同理心,建立跨专业网络和技能,并促进下一代医疗保健工作者的创新
- 批准号:
498310 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Operating Grants
関節リウマチ患者のSuccessful Agingに向けたフレイル予防対策の構築
类风湿性关节炎患者成功老龄化的衰弱预防措施的建立
- 批准号:
23K20339 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Life course pathways in healthy aging and wellbeing
健康老龄化和福祉的生命历程路径
- 批准号:
2740736 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Studentship
I-Corps: Aging in Place with Artificial Intelligence-Powered Augmented Reality
I-Corps:利用人工智能驱动的增强现实实现原地老龄化
- 批准号:
2406592 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Standard Grant
NSF PRFB FY 2023: Connecting physiological and cellular aging to individual quality in a long-lived free-living mammal.
NSF PRFB 2023 财年:将生理和细胞衰老与长寿自由生活哺乳动物的个体质量联系起来。
- 批准号:
2305890 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Fellowship Award
虚弱高齢者のSuccessful Agingを支える地域課題分析指標と手法の確立
建立区域问题分析指标和方法,支持体弱老年人成功老龄化
- 批准号:
23K20355 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
「ケア期間」に着目したbiological aging指標の開発
开发聚焦“护理期”的生物衰老指数
- 批准号:
23K24782 - 财政年份:2024
- 资助金额:
$ 42.51万 - 项目类别:
Grant-in-Aid for Scientific Research (B)