Efficient diagnostic tools to evaluate central auditory dysfunction

评估中枢听觉功能障碍的有效诊断工具

• 批准号: 9906220
• 负责人: David A. Eddins
• 金额: $ 44.59万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9906220
• 关键词: Area; Auditory; Auditory Perception; Auditory system; Brain Injuries; Central Auditory Diseases; Clinic; Clinical; Clinical assessments; Code; Computer Models; Computer software; Counseling; Data; Development; Diagnosis; Diagnostic; Diagnostic tests; Elements; Environment; Evaluation; Functional disorder; Future; Goals; Health; Hearing Tests; Human Resources; Laboratories; Lead; Link; Masks; Measures; Methodology; Modeling; Modernization; Neurosciences; Noise; Participant; Patients; Performance; Peripheral; Psychoacoustics; Questionnaires; Recording of previous events; Rehabilitation therapy; Research; Resources; Source; Speech; Stimulus; Structure; Techniques; Testing; Translations; Traumatic Brain Injury; Work; accurate diagnosis; auditory processing; clinical practice; cost; experience; flexibility; hearing impairment; improved; information processing; insight; instrument; normal hearing; novel; portability; predictive modeling; public health relevance; remediation; research clinical testing; sound; speech in noise; theories; tool

 DESCRIPTION (provided by applicant): Most diagnoses of hearing loss focus on the audiogram, which is not sensitive to dysfunction at many of the additional processing stages associated with auditory perception. For example, recent data from many laboratories, including our own, have shown clear auditory processing deficits both in older listeners and in patients who have suffered traumatic brain injury, despite normal audiograms. Modern auditory neuroscience, computational modeling, and psychoacoustics have provided great insight into the information processing that underlies auditory perception and have identified specific stimuli and tasks for the evaluation of central auditory function, but this information has largely remained in the laboratory. It is the goal of this proposal to develop and evaluate a set of clinicl tests that draw upon modern laboratory tests and theories of auditory system function. These will form the basis of a new clinical test battery for central auditory dysfunction that will suppot the accurate diagnosis of a much wider range of the difficulties that can lead to auditory complaints.

 描述（由申请人提供）：大多数听力损失的诊断集中在听力图上，听力图对与听觉感知相关的许多额外处理阶段的功能障碍不敏感。例如，最近来自许多实验室（包括我们自己的实验室）的数据显示，尽管听力图正常，但老年人和遭受创伤性脑损伤的患者都存在明显的听觉处理缺陷。现代听觉神经科学、计算建模和心理声学为听觉感知的信息处理提供了深刻的见解，并确定了用于评估中枢听觉功能的特定刺激和任务，但这些信息主要停留在实验室中。本提案的目的是开发和评估一套临床测试，借鉴现代实验室测试和听觉系统功能的理论。这些将形成一种新的中枢听觉功能障碍临床测试组合的基础，该组合将支持对可能导致听觉投诉的更广泛困难的准确诊断。

项目成果

A three-step pattern in audiometric thresholds.

听力阈值的三步模式。

• DOI: 10.1121/10.0003781
• 发表时间: 2021
• 期刊: JASA express letters
• 影响因子: 1
• 作者: Hoover,EricC

Clinical Importance of Binaural Information: Extending Auditory Assessment in Clinical Populations Using a Portable Testing Platform.

• DOI: 10.1044/2021_aja-20-00168
• 发表时间: 2021-09-10
• 期刊: American journal of audiology
• 影响因子: 1.8
• 作者: Diedesch AC;Bock SJA;Gallun FJ
• 通讯作者: Gallun FJ

Exponential spectro-temporal modulation generation.

• DOI: 10.1121/10.0003604
• 发表时间: 2021-03
• 期刊: The Journal of the Acoustical Society of America
• 作者: Stavropoulos TA;Isarangura S;Hoover EC;Eddins DA;Seitz AR;Gallun FJ
• 通讯作者: Gallun FJ

Development and validation of a Spanish-language spatial release from masking task in a Mexican population.

• DOI: 10.1121/10.0016850
• 发表时间: 2023-01
• 期刊: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
• 影响因子: 2.4
• 作者: Lelo de Larrea-Mancera, E. Sebastian;Solis-Vivanco, Rodolfo;Sanchez-Jimenez, Yolanda;Coco, Laura;Gallun, Frederick J.;Seitz, Aaron R.
• 通讯作者: Seitz, Aaron R.

Impaired Binaural Hearing in Adults: A Selected Review of the Literature.

• DOI: 10.3389/fnins.2021.610957
• 发表时间: 2021
• 期刊: Frontiers in neuroscience
• 影响因子: 4.3
• 作者: Gallun FJ