2020 Oxygen Radicals Gordon Research Conference (GRC) and Gordon Research Seminar (GRS)

2020年氧自由基戈登研究会议（GRC）和戈登研究研讨会（GRS）

• 批准号: 9912443
• 负责人: Yvonne M. W. Janssen-Heininger
• 金额: $ 2.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-22 至 2021-01-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9912443
• 关键词: Academia; Address; Age; Aging; Applications Grants; Applied Research; Area; Atmosphere; Award; Basic Science; Biology; California; Cell physiology; Cessation of life; Chemicals; Chemistry; Collaborations; Communication; Country; Diagnostic; Disease; Elevator; Endoplasmic Reticulum; Ensure; Environment; Ethnic Origin; Event; FDA approved; Failure; Fertilization; Fostering; Free Radicals; Functional disorder; Funding; Future; Gender; Goals; Government; Health; Homeostasis; Hour; Illinois; Incentives; Industry; Iron; Knowledge; Link; Lipids; Location; Medicine; Metabolic; Metabolism; Methodology; Mitochondria; Nationalities; Oral; Organelles; Oxidants; Oxidation-Reduction; Participant; Pharmaceutical Preparations; Play; Policies; Post-Translational Protein Processing; Postdoctoral Fellow; Published Comment; Reactive Oxygen Species; Regulation; Research; Research Personnel; Research Project Grants; Rhea; Role; Running; Scientist; Senior Scientist; Social Planning; Students; Therapeutic; Translations; Travel; Twitter; Underrepresented Minority; United States; United States National Institutes of Health; Universities; Vermont; Woman; base; career; career development; clinical development; cost; drug development; educational atmosphere; experience; graduate student; healthspan; innovation; inquiry-based learning; lectures; meetings; novel; peer; posters; programs; proteostasis; response; senescence; sensor; social; stem cells; symposium; therapeutic development; tool; tumor metabolism

Project Summary This conference grant proposal seeks funds for a Gordon Research Conference (GRC) on Oxygen Radicals: Chemical Reactivity, Metabolism, and Opportunities for Therapeutic Development to be held in Ventura CA February 2-7, 2020, in conjunction with a Gordon Research Seminar (GRS) for trainees, organized by two trainees (Cheryl van de Wetering, and Rhea Bovee), to be held immediate prior to the GRC, February 1-2, 2020 at the same location. We present an exciting program that brings together diverse fields of oxidant research, integrating recent discoveries of new oxidant species, with methodological advances, studies of biology, organelle dysfunction and metabolism, and aging, and plenary and round table discussions focusing on redox- based drugs in clinical development. The program includes senior scientists (giving the keynote lectures), as was as junior and mid-career scientists, and we have 10 slots for invited talks from submitted abstracts. Speakers are from academia, industry and the NIH, represent 19 countries and will be sharing their latest discoveries in nine sessions: Keynote session I: Oxygen Radicals: connecting chemistry with biology and medicine; Mitochondria from energy power houses to metabolite regulators; Oxygen radicals in stem cell function, senescence and aging; Redox in translation: Hurdles and ways forward toward therapeutics; Endoplasmic reticulum-redox control of proteostasis and dysregulation in disease; Reactive lipids in death, homeostasis and as therapeutics: Ferroptosis, and beyond; Advances in redox sensors, probes, and diagnostics; Oxygen radicals in metabolism; Keynote session II: Technical advances in the study of oxygen radicals; opportunities and challenges. Other conference highlights are the power hour and representation by women with a twitter feed #REDOXWOMEN and assurance that at least 40% of all presenters or discussion leaders are women. We will have elevator pitch sessions to highlight posters, and a policy of first questions by trainees. We will have welcome tables and social events to be inclusive of new attendees and continue the tradition of the Iron Bolt Award for the most notable comment. Collectively, this program will ensure a vibrant and collegial atmosphere to share the top discoveries in research on oxygen radicals, their involvement in disease and aging and potential avenues for therapeutic development.

项目总结