Mentoring Patient-Oriented Research: Sleep & Health During & After Hospital Stay

项目摘要 作为芝加哥大学的医学副教授， 健康中心和学术医院，我已经建立了一个研究计划， 以患者为导向的研究（POR），以开发和测试旨在改善护理的干预措施 用于患有睡眠和呼吸障碍的住院成人。我领导了两项重要的研究 芝加哥大学的培训项目（助理主任，医院学者 培训计划和共同主任，NIH资助的普利兹克医学院暑期研究 程序）。因此，我致力于继续指导博士前的学生，博士后， 博士生和这些领域的早期研究人员。有几 机构资源，如芝加哥大学转化医学研究所 （CTSA），睡眠代谢和健康中心，以及健康和社会中心 科学（CHeSS）及其相关的临床研究培训计划，以及 部门和司大力支持并致力于培训初级人员的使命 investigators.这些资源将确保成功地发展一个指导 在POR的计划，以了解和改善住院病人的健康，通过 解决睡眠障碍和改善急性病住院医疗患者的睡眠 当他们过渡回家。我在POR的职业目标是：1）获得与以下相关的新培训 我目前的项目包括长期随访临床研究，2）继续支持 我的研究基础设施和通过NIH资助的研究，3）继续我的合作 我和其他研究人员在睡眠领域进行了合作，这对我的工作和我的研究都很重要。 我的实习生我在辅导方面的职业目标是：1）获得正式的辅导培训 通过NIH CTSA和国家指导网络，2）从 经验丰富的导师，3）帮助我目前的学员获得K资金，5）采取 在奖学金，住院医生和学生级别的新学员。两者的总体目标 这项提案中的研究项目是测试干预措施是否能改善睡眠健康 卫生能改善出院病人的健康状况。建筑 在现有的NIH资助的基础设施，支持我的研究计划，具体的 研究目的是：（1）了解睡眠剥夺对老年人的长期影响。 医院;（2）测试是否教育和授权患者睡眠不足， 住院与出院后睡眠和健康的改善有关。该项目将 提供一个理想的培训环境，指导初级调查员在一个新的领域， POR。我们将利用临床，翻译和科学资源的大学， 芝加哥睡眠代谢和健康中心。该奖项将有足够的时间， 增加我的指导专业知识，提高我的研究技能，并帮助我指导 确保为指导和协助学员作出充分努力， 在职业发展和获得独立的资金。

Project Summary As an Associate Professor of Medicine at the University of Chicago Sleep Metabolism and Health Center and an academic hospitalist, I have established a research program in patient- oriented research (POR) to develop and test interventions that aim to improve care for hospitalized adults with sleep and respiratory disorders. I lead two important research training programs at the University of Chicago (Assistant Director, Hospitalist Scholars Training Program and co-Director, NIH-funded Pritzker Medical School Summer Research Program). As such, I am committed to continuing to mentor pre-doctoral students, post- doctoral students, and early-stage investigators in these areas. There are several institutional resources, such as the University of Chicago Institute of Translational Medicine (CTSA), the Sleep Metabolism and Health Center, and the Center for Health and the Social Sciences (CHeSS) and its' associated clinical research training programs, as well as the strong departmental and divisional support and commitment to the mission of training junior investigators. These resources will ensure the successful development of a mentoring program in POR to understanding and improving the health of hospitalized patients through addressing sleep disorders and improving sleep for acutely ill hospitalized medical patients as they transition home. My career goals in POR are: 1) to acquire new training relevant to my current projects including long-term follow up in clinical studies, 2) to continue to support my research infrastructure and studies via NIH funding, 3) to continue my collaborations with other investigators in the area of sleep which is essential for both my work and that of my trainees. My career goals in mentoring are: 1) to acquire formal mentoring training through the NIH CTSA and National Mentoring Network, 2) to expand training from experienced mentors, 3) to assist my current trainees in obtaining K funding, and 5) to take on new trainees at the fellowship, residency, and student levels. The overall aim of the two research projects in this proposal are to test whether interventions improving sleep health and hygiene can improve health outcomes of hospitalized patients after discharge. Building on existing NIH-funded infrastructure that supports my research program, the specific research aims are: (1) to understand the long-term consequences of sleep deprivation in the hospital; and (2) to test whether educating and empowering patients about sleep loss in the hospital is associated with improved sleep and health after discharge. This project will provide an ideal training environment for mentoring junior investigators in a novel field of POR. We will utilize the clinical, translational, and scientific resources of the University of Chicago Sleep Metabolism and Health Center. This award will allow sufficient time to increase my mentoring expertise, to enhance my research skills, and to help me guide trainees in POR studies by ensuring adequate effort for mentoring and for assisting trainees in career development and obtaining independent funding.