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Tetramers for Biodefense Research

Tetramers for Biodefense Research
用于生物防御研究的四聚体
批准号:
9915729
负责人:
JOHN ALTMAN
金额:
$122.72万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-03-21 至 2020-03-20

项目摘要

项目成果

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中文摘要
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英文摘要
The NIH Tetramer Facility provides custom synthesis and distribution of soluble major histocompatibility complex (MHC)-peptide tetramer reagents that can be used to detect antigen-specific T cells. These reagents include custom class I tetramers for mouse, non-human primate, and human alleles; class II reagents for mouse, non-human primate and human alleles; mouse and human CD1d tetramers; and human CD1a-c tetramers. The NIH Tetramer Facility also is developing novel technologies to improve production and expand the range of available MHC and CD1 tetramers. The tetramer reagents can be applied to studies ranging from basic immunology and protection against microbial pathogens to control of immune-mediated diseases and tumor metastases.
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Task Order B-5_75N93022F00002; 09/19/2022-03/20/2023; $18,543.00.
  • 批准号:
    10703781
  • 项目类别:
  • 资助金额:
    $1.85万
  • 财政年份:
    2020
  • 负责人:
    JOHN ALTMAN
  • 依托单位:
NIH TETRAMER CORE FACILITY (INFECTIOUS DISEASES OTHER THAN HIV/AIDS)
  • 批准号:
    10376128
  • 项目类别:
  • 资助金额:
    $200.18万
  • 财政年份:
    2020
  • 负责人:
    JOHN ALTMAN
  • 依托单位:
NIH TETRAMER CORE FACILITY (HIV/AIDS)
  • 批准号:
    10376127
  • 项目类别:
  • 资助金额:
    $30.0万
  • 财政年份:
    2020
  • 负责人:
    JOHN ALTMAN
  • 依托单位:
NIH Tetramer Core Facility
  • 批准号:
    10812213
  • 项目类别:
  • 资助金额:
    $148.79万
  • 财政年份:
    2020
  • 负责人:
    JOHN ALTMAN
  • 依托单位:
海外基金