Washington University Career Development Program in Drug Abuse and Addiction

摘要 K12计划的目标是支持和培训具有以下专业知识的下一代临床医生科学家 药物滥用和成瘾的遗传学。药物滥用研究正变得越来越复杂 多学科。来自单一学科的方法对推动科学和方法论做出了很大贡献 遗传学的技术进步确立了对日益多学科的需求 解决有关成瘾和人类健康中的遗传学的复杂问题的方法。带着这个 基础科学基因发现推进药物滥用和成瘾研究的潜力需要临床医生 可以通过翻译遗传学取得重要诊断和治疗进展的科学家 研究。为了实现这一计划的目标，我们确定了以下具体目标： 1.在华盛顿大学医学院(WUSM)增设2个学者教职，并 支持学者侧重于药物滥用和成瘾基因研究。第一位奖学金获得者将于 该计划的第一年。第二名奖学金获得者将在该计划的第三年招募。 2.制定针对学者的教学培训计划，以补充每个学者的个性 需求和兴趣。授课培训将利用现有的课程和研讨会。 在整个吴，大多数课程都集中在两个优秀的博士后研究培训 课程：临床调查理学硕士和人口健康科学硕士。 3.通过正式辅导，为学者提供短期和长期的研究指导 与不同教职员工的关系。 4.设计学者特定的职业发展计划，将重点放在关键的过渡阶段 向独立融资迈进一步。这项培训将通过助学金写作课程来完成，模拟 学习部分，以及指导。 5.建立全面的五NIDA K12项目评估体系。我们将评估 使用调查、访谈和其他指标的学者、导师、教员和培训计划。学者 将对职业发展进行长期跟踪，并进行独立的年度评估 由项目咨询委员会提供。 Wu NIDA K12计划将使我们能够利用现有的和非常成功的临床和 翻译研究培训计划，促进2名临床科学家的职业发展和研究 他的工作重点是药物滥用、成瘾和遗传学。这项计划将支持发展 能够竞争世界上最好的机构的教员职位并产生一批 努力大幅提高我们对药物滥用和成瘾的理解。

Abstract The goal of this K12 program is to support and train the next generation of clinician scientists with expertise in the genetics of drug abuse and addiction. Drug abuse research is becoming increasingly complex and multidisciplinary. Approaches from single disciplines have done much to advance science, and methodological and technological advances in genetics have established the need for increasingly multidisciplinary approaches to address complex questions about addiction and genetics in human health. Bringing this potential of basic science genetic discovery to advance drug abuse and addiction research requires clinician scientists who can make important diagnostic and therapeutic advances through translational genetics research. To accomplish the goals of this program, we have established the following specific aims: 1. Create 2 new scholar faculty positions at Washington University School of Medicine (WUSM) and support scholars focused on drug abuse and addiction genetic research. The first scholar will begin in Year 1 of the program. The second scholar will be recruited in Year 3 of the program. 2. Develop scholar-specific didactic training programs designed to complement each scholar’s individual needs and interests. The didactic training will make use of existing coursework and seminars offered across WU, with most courses centered around two outstanding post-doctoral research training programs: the Master of Science in Clinical Investigation and the Master of Population Health Sciences. 3. Provide short-term and long-term research mentorship for scholars through formal mentoring relationships with diverse faculty. 4. Design scholar specific career development plans that will include a focus on the critical transitional step to independent funding. This training will be accomplished through grant writing courses, mock study sections, and mentoring. 5. Establish a comprehensive system to evaluate the WU NIDA K12 Program. We will evaluate the scholars, mentors, faculty and training programs using surveys, interviews, and other metrics. Scholar career development will be tracked long-term, and an independent, annual evaluation will be conducted by the program Advisory Committee. The WU NIDA K12 Program will enable us to take advantage of existing and highly successful clinical and translational research training programs to promote career development and research of 2 clinician scientists whose work focuses on drug abuse and addiction and genetics. This program will support the development of researchers who can compete for faculty positions at the best institutions in the world and produce a body of work to substantially advance our understanding of drug abuse and addiction.