Social networks, social resources, and HIV transmission

社交网络、社会资源和艾滋病毒传播

• 批准号: 9916779
• 负责人: DANIELLE GERMAN
• 金额: $ 16.41万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9916779
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Adult; Advanced Development; Alcohol or Other Drugs use; Award; Baltimore; Behavior; Behavioral; Buffers; Caring; Characteristics; Church; Collection; Communicable Diseases; Communities; Community Networks; Crack Cocaine; Data; Data Analyses; Data Collection; Development; Empirical Research; Environment; Epidemic; Epidemiology; Ethnic Origin; Ethnic group; Evaluation; Exposure to; Face; Feasibility Studies; Foundations; Funding; Genetic; Geography; Goals; HIV; HIV Infections; HIV Seropositivity; HIV risk; Homelessness; Imprisonment; Individual; Injections; Institution; Intervention; Life; Maryland; Measurement; Measures; Mentored Research Scientist Development Award; Mentors; Methodology; Methods; Names; Outcome; Pathway interactions; Pattern; Persons; Pharmaceutical Preparations; Phylogenetic Analysis; Positioning Attribute; Poverty; Process; Publications; Race; Research; Research Methodology; Research Training; Resources; Risk; Risk Behaviors; Role; Scientist; Shapes; Social Concepts; Social Environment; Social Network; Social Work; Structure; Testing; Training; Travel; Unemployment; Unsafe Sex; Volunteer Organization; biobehavior; black men who have sex with men; care systems; career; cocaine use; community organizations; contextual factors; disease transmission; experience; improved; innovation; insight; pre-exposure prophylaxis; prevention service; programs; protective behavior; psychosocial; public health relevance; racial and ethnic; sex; skills; social; social capital; social metrics; social organization; social structure; socioeconomics; theories; therapy development; transmission process; virtual

 DESCRIPTION (provided by applicant): This application for a Mentored Research Scientist Development Award (K01) seeks support for development of a unique program of interdisciplinary independent research that combines social theories and research methods of social organization with that of infectious disease dynamics to study ways in which the social organization of communities may simultaneously impact access to social resources and transmission of infectious diseases including HIV. The K01 will support structured training, coursework, tutorials, intensive mentored relationships, and empirical research within a rigorous interdisciplinary institutional environment. Specific training objectives are to obtain: 1) expertie in sociometric network concepts, methods, and measures; 2) skills in phylogenetic analysis and infectious disease dynamics theories; and 3) expertise in the study of social organization and social capital; and to: 4) integrate new skills and concepts with current research to inform intervention development and seek funding as an independent scientist. The proposed training and research is a natural next career step that builds upon a background of social, behavioral, and epidemiological HIV and substance use research and is responsive to identified priorities for U.S. HIV prevention. The disproportionate and severe HIV epidemic among African-American men who have sex with men (AAMSM) requires an understanding of community social dynamics in order to advance development of interventions that integrate behavioral, structural, and biomedical components. A long-term goal is to understand how the social organization of AAMSM communities, their socio-economic stability, and their HIV transmission dynamics are interrelated to inform innovative HIV prevention and care interventions. The objective of this research is to examine HIV transmission pathways and access to social capital within AAMSM social and affiliation networks and establish a methodological, theoretical, and operational foundation for future research. Research specific aims are to: 1) evaluate HIV phylogenetic clustering and identify characteristics of persons in clusters with AAMSM; 2) determine presence and correlates of network social capital among AAMSM; and 3) characterize AAMSM affiliations with formal organizations and social settings and identify affiliation network influences on HIV and substance use. These hypotheses will be tested through examination of HIV genetic sequence data collected among approximately 2000 HIV-positive individuals in Maryland between 2012-2015, including an anticipated 38% AAMSM, and primary data collection with 300 adult AAMSM in Baltimore, Maryland. Findings will inform the approach and conceptual framework and provide skills for a broader R01 study examining pathways between social structures and HIV transmission. The research and training from the award will result in scientific publications that will provide insight into social and structural influences on HIV transmission among AAMSM and provide direction for intervention development.

 描述（由申请人提供）：本申请指导研究科学家发展奖（K01）寻求支持开发一个独特的跨学科独立研究计划，该计划将社会理论和社会组织的研究方法与传染病动力学相结合，以研究社区的社会组织可能同时影响社会资源的获取和包括艾滋病毒在内的传染病传播的方式。 K01 将在严格的跨学科机构环境中支持结构化培训、课程作业、教程、强化指导关系和实证研究。具体培训目标是获得： 1) 社会计量网络概念、方法和措施的专业知识； 2）系统发育分析和传染病动力学理论技能； 3）社会组织和社会资本研究方面的专业知识； 4) 将新技能和概念与当前研究相结合，为干预措施的开发提供信息并作为独立科学家寻求资金。拟议的培训和研究是自然的下一个职业步骤，它建立在社会、行为和流行病学艾滋病毒和药物使用研究的背景之上，并响应美国艾滋病毒预防的确定的优先事项。非洲裔美国男男性行为者 (AAMSM) 中艾滋病毒流行率不成比例且严重，需要了解社区社会动态，以推动整合行为、结构和生物医学成分的干预措施的制定。长期目标是了解 AAMSM 社区的社会组织、其社会经济稳定性以及艾滋病毒传播动态如何相互关联，为创新的艾滋病毒预防和护理干预措施提供信息。本研究的目的是检查 AAMSM 社交和附属网络中的 HIV 传播途径和获取社会资本的机会，并为未来的研究奠定方法、理论和操作基础。研究的具体目标是： 1) 评估 HIV 系统发育聚类并确定 AAMSM 人群的特征； 2）确定AAMSM之间网络社会资本的存在和相关性； 3) 描述 AAMSM 与正式组织和社会环境的隶属关系，并确定隶属网络对 HIV 和药物使用的影响。这些假设将通过检查 2012 年至 2015 年间在马里兰州约 2000 名 HIV 阳性个体中收集的 HIV 基因序列数据（包括预期的 38% AAMSM）以及对马里兰州巴尔的摩 300 名成人 AAMSM 收集的主要数据进行检验。研究结果将为方法和概念框架提供信息，并为更广泛的 R01 研究提供技能，以检查社会结构和艾滋病毒传播之间的途径。该奖项的研究和培训将产生科学出版物，深入了解 AAMSM 中艾滋病毒传播的社会和结构影响，并为干预措施的发展提供方向。

项目成果

Health Inequalities by Sexual Orientation: Results from the 2016-2017 Barcelona Health Survey.

按性取向划分的健康不平等：2016-2017 年巴塞罗那健康调查结果。

• DOI: 10.1089/lgbt.2021.0171
• 发表时间: 2022
• 期刊: LGBT health
• 影响因子: 4.8
• 作者: Marti-Pastor,Marc;German,Danielle;Perez,Gloria;Bartoll,Xavier;Diez,Elia;Pont,Angels;Garín,Olatz;Alonso,Jordi;Hernandez,Gimena;Mayoral,Karina;Zamora,Victor;Vilagut,Gemma;Ferrer,Montse
• 通讯作者: Ferrer,Montse