The short and long-term dynamics of opioid/stimulant use: Mixed methods to informoverdose prevention and treatment related to polysubstance use

阿片类药物/兴奋剂使用的短期和长期动态：与多物质使用相关的过量预防和治疗的混合方法

• 批准号: 10841942
• 负责人: DANIELLE GERMAN
• 金额: $ 16.27万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-30 至 2024-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10841942
• 关键词: Administrative Supplement; Baltimore; Collection; Communities; Complement; Data; Data Collection; Drug Interactions; Drug user; Ecological momentary assessment; Elements; Employment Status; German population; Goals; Imprisonment; Individual; Intervention; Interview; Knowledge; Legal; Legal system; Link; Long-Term Effects; Measures; Mediating; Methods; Opioid; Parents; Pathway interactions; Perception; Persons; Police; Police officer; Prevention; Recovery Support; Research Personnel; Role; Services; Substance Use Disorder; Time; cohort; effectiveness trial; experience; housing instability; parent project; polysubstance use; recovery services; recruit; response; skills; social determinants; stimulant use; substance use; treatment services

Project summary In response to NOT-DA-23-011, this administrative supplement will expand the scope of the parent project (R01DA057673, MPI: Genberg and German) on short and long-term effects of polysubstance use to incorporate collection of quantitative and qualitative data on criminal legal involvement. Specifically, this application will broaden and complement the skills of our investigative team to include researchers with expertise on characterizing the intersection of substance use and criminal legal involvement, with a focus on people who use drugs’ interaction with street-level police officers. The overall objective of this administrative supplement is to elucidate the relationship between polysubstance use and encounters with police and other elements of the criminal legal system in a community-recruited cohort of people who use drugs in Baltimore, MD. To date, most studies have only examined the association between polysubstance use and incarceration cross-sectionally, yet rigorous longitudinal data on the upstream drivers of incarceration, such as interactions with police, are lacking. Overcoming this knowledge gap is important as pre-arrest diversion is seen as a critical opportunity for police to link people who use drugs to community-based recovery services yet our understanding on police-PWUD interactions is limited with respect to polysubstance use. Thus, we intend to collect detailed quantitative and qualitative data on anticipated and realized experiences with street-level police (e.g. stopped, arrested, harassed) among PWUD by accomplishing the following specific aims to: 1) evaluate real-time associations between polysubstance use and the mediating role of social determinants (e.g. housing instability and employment status) on negative police encounters; and 2) characterize experiences, perceptions, and consequences of criminal legal involvement during polysubstance using episodes. We will accomplish Aim 1 by adding criminal legal involvement measures to ongoing data collection of ecological momentary assessments among 200 PWUD. To complement the quantitative results, we will conduct 20 in- depth interviews with PWUD who had recent encounters with street-level police to contextualize the findings in Aim 1. We will leverage findings from this supplement to inform an R34 preliminary effectiveness trial to pilot pre-arrest deflection to recovery support, MOUD, and wrap-around services for people with severe substance use disorder, including individuals who engage in polysubstance use.

项目总结 为响应NOT-DA-23-011，本行政补充文件将扩大母项目的范围 (R01DA057673，MPI：Genberg和德国)关于多物质使用的短期和长期影响 纳入关于刑事法律参与的定量和定性数据的收集。具体地说，这 应用程序将拓宽和补充我们调查团队的技能，包括具有 在描述物质使用和刑事法律参与的交集方面的专门知识，重点是 吸毒者与街头警察的互动。这项管理的总体目标是 补充说明使用多种物质与遭遇警察和其他人之间的关系 巴尔的摩社区招募的吸毒者队列中的刑事法律体系元素， 马里兰州到目前为止，大多数研究只检查了多种物质的使用和监禁之间的联系 关于监禁的上游驱动因素的横向、但严格的纵向数据，如相互作用 与警察，是缺乏的。克服这一知识差距很重要，因为逮捕前的转移被视为一种 警方有重要机会将吸毒者与社区康复服务联系起来，但我们的 对警察和残障人士相互作用的了解仅限于多物质的使用。因此，我们打算 收集与街头警察合作的预期和已实现经验的详细定量和定性数据 (例如，阻止、逮捕、骚扰)通过实现以下具体目标来实现：1)评估 多种物质使用与社会决定因素(例如住房)的中介作用之间的实时关联 不稳定和就业状况)；和2)描述经历， 多物质使用事件中刑事法律介入的认知和后果。我们会 通过将刑事法律介入措施添加到正在进行的生态数据收集中，实现目标1 在200名PWUD中进行了瞬时评估。为了补充量化结果，我们将在以下方面进行20项研究： 对最近与街头警察有过接触的PWUD进行了深入采访，以将调查结果与 目标1.我们将利用本附录中的发现为R34初步有效性试验提供指导 针对严重疾病患者的逮捕前偏向康复支持、Moud和环绕式服务 使用障碍，包括从事多物质使用的个人。