Massively parallel sequencing and PCR optimised for DNA-based diagnostics and discovery

下一代医学诊断和疾病研究中的发现将涉及聚合酶链式反应和�下一代�测序的结合，前者是一种用于从少量起始数量中扩增大量DNA的工具，后者是一种在单一仪器上对大量DNA进行测序的方法。这项研究旨在描述使科学家能够高精度、高效率地同时对数百人的数百个疾病基因进行筛查的方法。

The next generation of medical diagnostics and discovery in disease research will involve the marriage of PCR, a tool used to amplify large amounts of DNA from small starting quantities, and �next generation� sequencing, a way to sequence lots and lots of DNA on a single instrument run. This study aims to describe methods which allow scientists to screen hundreds of disease genes in hundreds of people simultaneously with high accuracy and high efficiency.