Identifying the missing heritability of breast cancer.

确定乳腺癌缺失的遗传力。

• 批准号: nhmrc : 1025145
• 负责人: A/Pr Daniel Park
• 金额: $ 30.75万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-missing-heritability-breast-cancer/110411
• 关键词: Identifying; missing; heritability; breast; cancer.

One of the strongest risk factors for the development of breast cancer is having a close relative with the disease. Some advances have been made in understanding the specific genetic factors that underlie this susceptibility but these known genetic factors only explain about a third of the overall familial effects. This research will utilise our prior research, international research resources, new technology and supercomputing to identify the majority of genetic factors associated with breast cancer susceptibility.

乳腺癌发病的最大风险因素之一是与疾病有密切关系。在了解这种易感性的具体遗传因素方面已经取得了一些进展，但这些已知的遗传因素只能解释大约三分之一的整体家族效应。这项研究将利用我们以前的研究，国际研究资源，新技术和超级计算来确定与乳腺癌易感性相关的大多数遗传因素。