High risk genes for prostate cancer

在识别前列腺癌易感性的遗传因素方面已经取得了一些进展，但很少能解释家族中的多个前列腺癌病例。连锁研究表明，前列腺癌无法解释的家族聚集性很可能可以通过许多基因的突变来解释。这项研究将利用我们之前的研究、我们广泛的研究资源、新技术和超级计算来确定与前列腺癌易感性相关的遗传因素。

Some advances have been made in identifying genetic factors that underlie susceptibility to prostate cancer but few explain multiple-cases of prostate cancer in families. Linkage studies show that the unexplained familial aggregations of prostate cancer are likely to be explained by mutations in many genes. This research will utilize our prior research, our extensive research resources, new technology and supercomputing to identify genetic factors associated with prostate cancer susceptibility.