High risk genes for prostate cancer

前列腺癌的高危基因

• 批准号: nhmrc : 1028280
• 负责人: A/Pr Daniel Park
• 金额: $ 38.73万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/high-risk-genes-prostate-cancer/110622
• 关键词: risk; genes; prostate; cancer

Some advances have been made in identifying genetic factors that underlie susceptibility to prostate cancer but few explain multiple-cases of prostate cancer in families. Linkage studies show that the unexplained familial aggregations of prostate cancer are likely to be explained by mutations in many genes. This research will utilize our prior research, our extensive research resources, new technology and supercomputing to identify genetic factors associated with prostate cancer susceptibility.

在确定前列腺癌易感性的遗传因素方面已经取得了一些进展，但很少有人解释家族中的多例前列腺癌。连锁研究表明，原因不明的前列腺癌家族聚集性很可能是由许多基因突变解释的。这项研究将利用我们以前的研究，我们广泛的研究资源，新技术和超级计算来确定与前列腺癌易感性相关的遗传因素。