An Online Short-Course in Sample-Size Determination - A Practical Guide to Improving Reproducibility through Proper Planning
An Online Short-Course in Sample-Size Determination - A Practical Guide to Improving Reproducibility through Proper Planning
批准号:
9925089
负责人:
Robert Joseph Calin-Jageman
金额:
$1.79万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-05-01 至 2023-04-30
关键词:
Active LearningAddressAdoptedAreaAttitudeBayesian MethodBehavioralBiomedical ResearchBudgetsCollectionCompetenceDevelopmentEducational CurriculumElementsEnsureEthicsExerciseFeedbackFosteringFoundationsFunctional Magnetic Resonance ImagingFundingGene Expression ProfilingGoalsHeadKnowledgeLearningMeasuresMethodologyMethodsModelingParticipantPre-Post TestsProblem SolvingProfessional OrganizationsPublishingReadingReproducibilityResearchResearch PersonnelSample SizeSamplingScienceSelf EfficacySlideStandardizationSystemTestingTrainingTraining ActivityTranslationsUnited States National Institutes of HealthWorkbasecohortimprovedjournal articlelearning materialslecturerlecturesonline coursepre-clinicalpre-clinical researchpublic health interventionsimulationsocial mediasoundtranscriptome sequencingwasting
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Sample-size planning is currently the Achilles heel of biomedical research. Many fields of preclinical research
routinely rely on inadequate samples, leading to waste, excessive false-positives, and inflated effect sizes.
These practices persist because researchers often eschew sound sample-size planning for easy but invalid
approaches. To help address this critical issue, this project will produce a self-guided online course that will
help trainees exchange poor sample-size determination practices for sound approaches. The course will a)
help redirect researchers away from erroneous approaches by making clear their severe negative
consequences, b) will dispel common misconceptions that discourage sound sample-size planning, and c) will
provide exercises with instant feedback to build self-efficacy for independent sample-size planning. The
materials will be produced for a modest budget, will incorporate guidance from a team of renowned
methodological experts, and will be anchored in a proven behavioral-change approach. The course will
provide a needed supplement to current materials, which do not adequately teach sample-size determination.
A thoughtful piloting plan will enable extensive feedback from diverse stakeholders to ensure strong impact not
only on knowledge but also on attitudes and actual competency. Dissemination will be supported through
partnerships with professional societies and the extensive social media reach of the participating guest
lecturers. Funding this proposal can have a strong positive impact on rigor and reproducibility in preclinical
research.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
Better Inference in Neuroscience: Test Less, Estimate More.
神经科学中更好的推理:更少测试,更多估计。
DOI:
10.1523/jneurosci.1133-22.2022
发表时间:
2022
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
[Calin-Jageman,RobertJ]
通讯作者:
Calin-Jageman,RobertJ
Mechanisms in the Expression and Decay of Long-Term Habituation Memory
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批准号:7939545
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项目类别:
-
资助金额:$36.24万
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财政年份:2010
-
负责人:Robert Joseph Calin-Jageman
-
依托单位:
海外基金