Comorbidity: Substance Use Disorders and Other Psychiatric Conditions

合并症：药物使用障碍和其他精神疾病

• 批准号: 9925206
• 负责人: MATT G KUSHNER
• 金额: --
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9925206
• 关键词: Substance Use Disorder; comorbidity

Abstract Introduction: This is a renewal application for T32 institutional training grant application – Comorbidity: Substance Use Disorders and Other Psychiatric Conditions (NIDA DA037183) -- following the completion of its first five-year funding cycle. Among the current portfolio of NIDA funded training grants, only one program other than ours (Dartmouth) has comorbidity as a primary focus. This is striking given co-occurrence prevalence of Substance Use Disorders (SUD) with other psychiatric conditions and health conditions (e.g. diabetes), and the extent to which either SUD or the comorbid disorder can go under- or untreated in conventional treatment settings. The goals, elements and resources of the renewal program retains critical and effective elements of the initial funding period while incorporating important lessons learned. Long term goals: The proposed program will develop a cadre of scientists with research expertise in comorbidity mechanisms, antecedents and correlates, diagnostics, and psychosocial and pharmacological interventions. Component objectives are to provide each trainee with a working knowledge of comorbidity research including: (a) translational science from Early Phase Clinical Trials to Community Based Participatory Research perspectives; (b) effective research strategies for comorbid conditions across populations and ethnic and cultural groups (e.g. American Indian, Hmong, Somali). Accomplishing programmatic features will capitalize on (a) the spectrum of faculty expertise providing mentoring across multiple areas, and (b) integration across training programs and departments. Key Elements: (1) Involvement of scientists and clinicians with diverse expertise and a core internal advisory group. Primary sites (4 postdoctoral trainees, 2 yrs each) are the Departments of Psychiatry and Psychology (UMN Twin Cities) and Family Medicine and Biobehavioral Health (UMN Duluth); (2) Recruitment, including under represented group outreach, of rigorously screened PhD and MD candidates with SUD and comorbidity as primary career focus; (3) Training with an interdisciplinary mentoring team (primary & 2 secondary mentors) with complementary expertise; (4) Formal training plans with clear milestones including trainee development of an NIH application initiated in Year 1; (5) Active research, seminars, didactic course work, workshops, and development of management, ethics, and regulatory expertise; (6) Dynamic program administration entailing monitoring with enhancements and problem resolution along with continued contact with trainees after completion and; (7) Annually convened external advisory group. Resources: Mentor funding sources include NIH Institutes, NSF, Minnesota Medical Foundation, and pharmaceutical industry. Key Personnel and Primary Mentors are directors of clinics, centers, or departments with significant resources.

摘要 简介：这是T32机构培训补助金申请的续签申请--共病： 物质使用障碍和其他精神疾病(NIDA DA037183)--在完成其 第一个五年筹资周期。在目前由NIDA资助的培训赠款组合中，只有一个方案 除了我们(达特茅斯)，共病是主要的焦点。考虑到同时发生的情况，这是令人震惊的 物质使用障碍(SUD)的患病率与其他精神疾病和健康状况(如 糖尿病)，以及SUD或共病疾病在多大程度上可能得不到或未得到治疗 常规治疗设置。更新计划的目标、要素和资源保持关键和 在纳入重要经验教训的同时，加强初期筹资期间的有效内容。长期目标： 拟议的计划将培养一支在共病机制方面具有研究专长的科学家队伍， 前置因素和相关因素、诊断、心理社会和药物干预。组件 目标是向每个受训人员提供关于共病研究的实用知识，包括：(A) 从早期临床试验到社区参与性研究的转化科学 观点；(B)针对人口和族裔共存状况的有效研究战略 文化群体(如美国印第安人、苗族、索马里人)。实现编程功能将利用 (A)在多个领域提供指导的教师专业知识的范围，以及(B)跨领域的整合 培训计划和部门。关键要素：(1)科学家和临床医生的参与 专业知识和核心内部咨询小组。主要地点(4名博士后实习生，每人2年)是 精神病学和心理学系(曼彻斯特大学双城)和家庭医学与生物行为健康 (2)招聘经过严格筛选的博士和 以自发性精神障碍和合并症为主要职业重点的MD候选人；(3)跨学科培训 具有互补专业知识的指导团队(主要导师和2名二级导师)；(4)正式培训计划，包括 明确的里程碑，包括第一年启动的学员开发NIH应用程序；(5)积极研究， 研讨会、授课工作、研讨会以及管理、道德和监管方面的发展 专业知识；(6)动态计划管理，通过增强和解决问题来进行监控 以及在完成培训后继续与受训人员联系；以及；(7)每年召开外部咨询会议 一群人。资源：Mentor资金来源包括NIH研究所、NSF、明尼苏达医学基金会和 制药业。关键人员和主要导师是诊所、中心或部门的主任 拥有大量的资源。