Non-contact In-Bed Sensing of Heart Failure Decompensation

心力衰竭失代偿的非接触式床上传感

基本信息

  • 批准号:
    10189423
  • 负责人:
  • 金额:
    $ 22.36万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-03-15 至 2023-03-14
  • 项目状态:
    已结题

项目摘要

PROJECT ABSTRACT: Chronic heart failure is a highly prevalent and costly disease marked by frequent exacerbations leading to recurrent hospitalizations. Heart failure patients have extraordinarily high hospitalization rates for fluid overload, which can often be avoided if exacerbations are detected early and diuretic therapy is intensified in the outpatient setting. Unfortunately, self- measurement of weights and self-reporting of symptoms have proven ineffective. The utility of home monitoring technologies has been limited by poor adherence to self-measurement, self- transmission of data, or self-application of wearables. Implantable devices have shown success but are invasive and expensive. Non-contact sensors are currently position-dependent and not compatible with multiple persons sleeping in the same bed. Nightingale Labs was founded to commercialize a non-contact adherence-independent sensor called Bedscales. Our preliminary results show that the low-profile mechanical sensors, when placed beneath the legs of a home bed, can perform adherence-independent sensing of total body weight, movements, respirations, and cardiac signals for months without patient interaction, even if the bed is shared by partners or pets. The overall goal of this Phase I SBIR is to define sensor accuracy in a real- world heart failure population in preparation for a prospective clinical study in Phase 2. By defining the signatures of impending hospitalization, BedScales aims to make outpatient management of heart failure a data-driven science.
项目摘要: 慢性心力衰竭是一种高度流行和昂贵的疾病,其特征是频繁加重 导致反复住院。心力衰竭患者有非常高的 因液体过多而住院的比率,如果检测到病情加重,通常可以避免 在门诊加强早期利尿治疗。不幸的是,自我- 体重的测量和症状的自我报告已被证明是无效的。的效用 家庭监控技术已经受到对自我测量、自我监控 数据传输或可穿戴设备的自我应用。植入式设备已经显示出成功 但是是侵入性的并且昂贵。非接触式传感器目前依赖于位置,而不是 适合多人睡在同一张床上。南丁格尔实验室成立的目的是 商业化一种称为Bedscales的非接触式粘附独立传感器。我们的初步 结果表明,当放置在房屋的腿下时, 床,可以执行总体重,运动, 呼吸和心脏信号长达数月,即使与患者共用病床, 伴侣或宠物。第一阶段SBIR的总体目标是在一个真实的环境中定义传感器精度, 全球心力衰竭人群,为II期前瞻性临床研究做准备。通过 定义即将住院的签名,BedScales旨在使门诊病人 心力衰竭的管理是一门数据驱动的科学。

项目成果

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Raymond C Chan其他文献

ANTIBIOTICS FOR CHOLANGITIS
治疗胆管炎的抗生素
  • DOI:
  • 发表时间:
    1989
  • 期刊:
  • 影响因子:
    0
  • 作者:
    G. French;Raymond C Chan;S. Chung;J. Leung
  • 通讯作者:
    J. Leung
ASHP Guidelines on the Design of Database-Driven Clinical Decision Support: Strategic Directions for Drug Database and Electronic Health Records Vendors.
ASHP 数据库驱动的临床决策支持设计指南:药物数据库和电子健康记录供应商的战略方向。

Raymond C Chan的其他文献

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{{ truncateString('Raymond C Chan', 18)}}的其他基金

Feasibility of early detection of infection and sepsis in the home
在家中早期发现感染和败血症的可行性
  • 批准号:
    10706940
  • 财政年份:
    2023
  • 资助金额:
    $ 22.36万
  • 项目类别:
Genomic Stability Functions of SMC Proteins in Germ Cells
生殖细胞中 SMC 蛋白的基因组稳定性功能
  • 批准号:
    8328637
  • 财政年份:
    2011
  • 资助金额:
    $ 22.36万
  • 项目类别:
Genomic Stability Functions of SMC Proteins in Germ Cells
生殖细胞中 SMC 蛋白的基因组稳定性功能
  • 批准号:
    8499369
  • 财政年份:
    2011
  • 资助金额:
    $ 22.36万
  • 项目类别:
Genomic Stability Functions of SMC Proteins in Germ Cells
生殖细胞中 SMC 蛋白的基因组稳定性功能
  • 批准号:
    8040406
  • 财政年份:
    2011
  • 资助金额:
    $ 22.36万
  • 项目类别:
THE IDENTIFICATION OF SMC-5 ASSOCIATED PROTEINS IN C ELEGANS BY CO-IMMUNOPRECIP
联合免疫法鉴定线虫中 SMC-5 相关蛋白
  • 批准号:
    8171407
  • 财政年份:
    2010
  • 资助金额:
    $ 22.36万
  • 项目类别:
THE IDENTIFICATION OF SMC-5 ASSOCIATED PROTEINS IN C ELEGANS BY CO-IMMUNOPRECIP
联合免疫法鉴定线虫中 SMC-5 相关蛋白
  • 批准号:
    7957779
  • 财政年份:
    2009
  • 资助金额:
    $ 22.36万
  • 项目类别:
THE IDENTIFICATION OF SMC-5 ASSOCIATED PROTEINS IN C ELEGANS BY CO-IMMUNOPRECIP
联合免疫法鉴定线虫中 SMC-5 相关蛋白
  • 批准号:
    7723668
  • 财政年份:
    2008
  • 资助金额:
    $ 22.36万
  • 项目类别:

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激素治疗、绝经年龄、既往产次和 APOE 基因型会影响老年人的认知。
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