Partnership in Implementation Science for Geriatric Mental Health (PRISM)

摘要 拟议的老年精神健康实施科学伙伴关系(PRISM)的总体目标 项目是建立一个中心，整合执行研究，以扩大可持续的、以证据为基础的规模 心理健康干预与东亚研究能力建设活动。拟议的精神健康 总部位于泰国的实施研究中心包括中国，该中心将专注于缩小 治疗和支持一般居住在社区的老年人，以及患有阿尔茨海默病和 特别是与痴呆症(在本提案中称为痴呆症)相关。具体目标是：1) 经验性地测试文化适应的成果获取(GTO)实施支持模式，旨在 加强循证体育运动干预的实施，缩小治疗差距 泰国有痴呆行为和心理症状的老年人(GTO-泰语)； 建立个人和机构能力，以实施#年心理健康干预研究 泰国和中国；3)提高泰国和中国政策制定者的研究证据能力 知情决策(EIDM)；4)建立一个知识库，供利益攸关方在 每个国家以及通过NIMH和其他区域NIMH中心与其他国家合作；以及，5)与 NIMH计划工作人员，通过科学和方案参与，通过合作协议 所有项目活动的实施。泰国公共事务部将重点放在老年人身上 健康已经确定了老年人心理健康治疗差距的缩小，特别是对于那些 将痴呆症及其家庭照顾者作为国家的关键优先事项，因为痴呆症病例的数量不断上升。 痴呆症，伴随着泰国快速增长的老龄化人口。该中心将汇聚泰国和泰国 中国跨学科研究人员、政策制定者和非政府组织从业人员与美国研究人员 彼此之间以及与研究人员和政策部门有成功的研究合作历史 参与国的制造商。具体的项目目标将分三个阶段实施。《伊始》 阶段(学习第一年)将涉及：在波士顿马萨诸塞州BWH建立行政核心；制定 在研究地点实施的详细研究方案(泰国)；对以下方面进行评估 准备好在两国实施创新的心理健康干预解决方案；以及 联系并探索与NIMH其他区域枢纽合作的可能性。实施 阶段(研究第2-4年)将涉及试验和进行实施以及扩大研究活动 (泰国)和执行能力建设计划(泰国和中国)。最后阶段(第4-5学年) 将致力于评估、数据共享和传播。 1

Abstract The overall goal of the proposed Partnership in Implementation Science for Geriatric Mental Health (PRISM) project is to establish a hub to integrate implementation research for scaling up sustainable, evidence-based mental health interventions with research capacity-building activities for East Asia. The proposed mental health implementation research hub, based in Thailand and including China, will focus on reducing the gap in treatment and support for community-residing older adults in general, and elders with Alzheimer's disease and related dementias (to be referred to as dementia in this proposal) in particular. Specific aims are to: 1) empirically test a culturally adapted Getting-To-Outcomes (GTO) implementation support model aimed at enhancing the delivery of an evidence-based physical exercise intervention for narrowing the treatment gap for older persons with behavioral and psychological symptoms of dementia (BPSD) in Thailand (GTO-ThAI); 2) build individual and institutional capacity for the implementation of mental health intervention research in Thailand and China; 3) improve Thai and Chinese policy makers' capacity for using research for evidence informed decision making (EIDM); 4) develop a knowledge base for shared learning among stakeholders within each country and with other countries through NIMH and other regional NIMH hubs; and, 5) collaborate with NIMH program staff, through scientific and programmatic involvement, through a cooperative agreement for the implementation of all project activities. The focus on older adults was made as the Thai Ministry of Public Health has identified the reduction in the mental health treatment gap for older adults, specifically, for those with dementia and their family caregivers, as a key priority for the nation, due to the rising number of cases of dementia, concomitant with Thailand's rapidly growing aging population. The hub will bring together Thai and Chinese interdisciplinary researchers, policy-makers and NGO practitioners with US-based researchers who have a history of successful research collaborations with each other as well as with researchers and policy makers in the participating countries. Specific project aims will be implemented in three phases. The inception phase (study year 1) will involve: establishing the Administrative Core at BWH, Boston MA; developing a detailed research protocol for implementation at the research sites (Thailand); conducting an assessment of readiness for implementation of innovative mental health intervention solutions in both countries; and, making contacts and exploring possibilities for collaboration with other NIMH regional hubs. The implementation phase (study years 2-4) will involve piloting and conducting the implementation and scale up research activities (Thailand) and implementing the capacity-building plan (Thailand and China). The final stage (study years 4-5) will be devoted to evaluation, data sharing, and dissemination. 1