Border Biomedical Research Center

总体总结 得克萨斯大学埃尔帕索分校(UTEP)，通过少数民族机构研究中心的支持 (RCMI)创建了边境生物医学研究中心(BBRC)，以解决拉美裔健康问题 我们称之为Borderplex的得克萨斯州西部边远地区独有的差异。在这项提案中，UTEP开发了 由来自地区学术、医疗和社区的专家组成的广泛的合作者队伍 合作目标是解决我们大多数墨西哥裔美国人普遍存在的癌症健康差距 人口。当与我们的姐妹城市墨西哥华雷斯结合在一起时，我们代表着最大的两国 世界上最大的社区，有近300万人。这个应用程序的总体目标是开发、增长和 维持BBRC现有的基础设施和计划，以及招募、培训和发展癌症 科学家和卫生从业者推动高质量的癌症研究并将有意义的发现转化为 回到社区。通过指导、试点计划和增强的研究基础设施，我们寻求 提高研究人员在获得外部资金以解决区域疾病差异方面的竞争力。 我们还寻求创造一个环境，为本科生和研究生创造进入 生物医学职业，并成为拉美裔和其他代表性不足的少数族裔进入 这个国家的生物医学劳动力。这些成果将通过实现五个具体目标来实现 目标是：(1)通过创新(A)基础；(B)行为；或(C)为癌症研究做出贡献 在我们地理上与世隔绝、服务不足的墨西哥裔美国人中进行的临床研究。增加了 强调流行病学以及与临床和公共卫生专家的合作是在 该大学的使命是解决其服务人群中紧迫的健康问题的更广泛范围。(2) 加强研究基础设施，从而加强BBRC调查员的能力，办法是：(A)加强 现有的多用户核心设施，用于与蛋白质、DNA、细胞培养、生物信息库、生物统计和 生物信息学；(3)招聘有经验的教员以解决癌症健康问题；(4)促进 BBRC调查员的专业发展和指导，包括通过(A)培训/教育获得博士后； (B)以我们的癌症项目主题为重点的试点赠款方案，并通过跨学科研究，解决 重要的健康差距问题和(5)，促进有意义的社区伙伴关系，以参与和招募 参加研究研究，并通过社区活动扩大外联和传播努力， 为我们的科学专业人员举办的讨论、研讨会和国际研讨会，以分享研究成果和最佳 练习。基础设施增强中包括支持研究的物理工厂组件，以及 行政核心，执行方案组成部分的协调、管理和治理，以及 评估部分，以确保实现方案和边界卫生目标，并最终 开发新的方法，以减少我们代表性不足人群中的癌症健康差距。

OVERALL SUMMARY The University of Texas at El Paso (UTEP), through support from the Research Centers at Minority Institutions (RCMI) has created the Border Biomedical Research Center (BBRC) to address issues of Hispanic Health Disparities unique to the far West Texas region that we call the Borderplex. In this proposal UTEP has developed an extensive cadre of collaborators consisting of experts from regional academic, medical, and community partners with the goal to address cancer health disparities that permeate our majority Mexican American population. When combined with our sister city of Ciudad Juarez, Mexico, we represent the largest binational community in the world, with nearly 3 million people. The overall goal for this application is to develop, grow and sustain the extant infrastructure and programs of the BBRC, as well as to recruit, train, and develop cancer scientists and health practitioners to promote high quality cancer research and to translate meaningful findings back to the community. Through mentoring, pilot programs, and enhanced research infrastructure we seek to promote investigator competitiveness in acquiring extramural funding to address regional disease disparities. We also seek to generate an environment that creates pipelines for undergraduate and graduate students into biomedical careers and serves as a major point of entry for Hispanics and other underrepresented minorities into the nation’s biomedical workforce. These outcomes will be obtained through the achievement of five specific objectives which are to: (1) Contribute, to cancer research through innovative (a) basic; (b) behavioral; or (c) clinical studies within our geographically isolated and underserved Mexican American population. Increased emphasis on epidemiology and collaborations with clinical and public health specialists is within the context of the University’s mission to address the broader scope of pressing health problems in its service population. (2) Strengthen research infrastructure and, thereby, capabilities of BBRC investigators through (a) enhancement of extant multi-user core facilities for research related to proteins, DNA, cell culture, biorepository, biostatistics and bioinformatics; (3) Recruit experienced faculty members to address cancer health issues; (4) Facilitate the professional development and mentoring of BBRC investigators, including postdocs via (a) training/education, (b) pilot grant programs focusing on our cancer project themes, and through interdisciplinary research, address important health disparity issues and (5), Promote meaningful community partnerships to engage and recruit participants for research studies and augment outreach and dissemination efforts, through community events, discussions, seminars, and international symposia for our scientific professionals to share findings and best practices. Included in infrastructure enhancement are physical plant components that support research, an administrative core to carry out coordination, management and governance of program components, an evaluative component to ensure programmatic and border health objectives are achieved, and ultimately the development of new approaches to reduce cancer health disparities in our underrepresented population.