Border Biomedical Research Center

总体汇总 德克萨斯大学埃尔帕索分校（UTEP），通过少数民族机构研究中心的支持 （RCMI）创建了边境生物医学研究中心（BBRC），以解决西班牙裔健康问题 德克萨斯州遥远的西部地区（我们称之为“边境”）所特有的差异。在这份提案中，UTEP开发了 由来自区域学术、医学和社区的专家组成的广泛的合作者骨干 合作伙伴的目标是解决癌症健康的差距，渗透到我们大多数墨西哥裔美国人 人口当与我们的姐妹城市墨西哥华雷斯城结合在一起时，我们代表了最大的两国 世界上有近300万人。该应用程序的总体目标是开发、增长和 维持BBRC现有的基础设施和计划，以及招募，培训和发展癌症 科学家和卫生从业人员，以促进高质量的癌症研究和翻译有意义的发现 回到社区。通过指导、试点项目和增强的研究基础设施， 提高研究者在获得院外资金方面的竞争力，以解决地区疾病差异。 我们还寻求创造一个环境，为本科生和研究生创造进入 生物医学职业，并作为西班牙裔和其他代表性不足的少数民族进入的主要切入点 国家的生物医学劳动力。这些成果将通过实现五个具体目标来实现。 目标是：（1）通过创新（a）基础;（B）行为;或（c） 在我们地理上孤立和服务不足的墨西哥裔美国人中进行的临床研究。增加 强调流行病学以及与临床和公共卫生专家的合作是在以下背景下进行的： 大学的使命，以解决其服务人口紧迫的健康问题的更广泛的范围。（二） 加强研究基础设施，从而加强北大西洋公约组织区域中心调查人员的能力，办法是：（a）加强 现有的多用户核心设施，用于蛋白质、DNA、细胞培养、生物储存库、生物统计学和 生物信息学;（3）招募有经验的教师来解决癌症健康问题;（4）促进 通过（a）培训/教育， (b)试点赠款计划侧重于我们的癌症项目的主题，并通过跨学科的研究，解决 重要的健康差距问题和（5），促进有意义的社区伙伴关系， 参与者进行研究，并通过社区活动加强外联和传播工作， 讨论会，研讨会和国际研讨会，我们的科学专业人员分享发现和最好的 实践基础设施的改进包括支持研究的物理工厂组件， 行政核心，对方案各组成部分进行协调、管理和治理， 评估组成部分，以确保实现方案和边境卫生目标，并最终 开发新的方法来减少我们代表性不足的人群中的癌症健康差异。

OVERALL SUMMARY The University of Texas at El Paso (UTEP), through support from the Research Centers at Minority Institutions (RCMI) has created the Border Biomedical Research Center (BBRC) to address issues of Hispanic Health Disparities unique to the far West Texas region that we call the Borderplex. In this proposal UTEP has developed an extensive cadre of collaborators consisting of experts from regional academic, medical, and community partners with the goal to address cancer health disparities that permeate our majority Mexican American population. When combined with our sister city of Ciudad Juarez, Mexico, we represent the largest binational community in the world, with nearly 3 million people. The overall goal for this application is to develop, grow and sustain the extant infrastructure and programs of the BBRC, as well as to recruit, train, and develop cancer scientists and health practitioners to promote high quality cancer research and to translate meaningful findings back to the community. Through mentoring, pilot programs, and enhanced research infrastructure we seek to promote investigator competitiveness in acquiring extramural funding to address regional disease disparities. We also seek to generate an environment that creates pipelines for undergraduate and graduate students into biomedical careers and serves as a major point of entry for Hispanics and other underrepresented minorities into the nation’s biomedical workforce. These outcomes will be obtained through the achievement of five specific objectives which are to: (1) Contribute, to cancer research through innovative (a) basic; (b) behavioral; or (c) clinical studies within our geographically isolated and underserved Mexican American population. Increased emphasis on epidemiology and collaborations with clinical and public health specialists is within the context of the University’s mission to address the broader scope of pressing health problems in its service population. (2) Strengthen research infrastructure and, thereby, capabilities of BBRC investigators through (a) enhancement of extant multi-user core facilities for research related to proteins, DNA, cell culture, biorepository, biostatistics and bioinformatics; (3) Recruit experienced faculty members to address cancer health issues; (4) Facilitate the professional development and mentoring of BBRC investigators, including postdocs via (a) training/education, (b) pilot grant programs focusing on our cancer project themes, and through interdisciplinary research, address important health disparity issues and (5), Promote meaningful community partnerships to engage and recruit participants for research studies and augment outreach and dissemination efforts, through community events, discussions, seminars, and international symposia for our scientific professionals to share findings and best practices. Included in infrastructure enhancement are physical plant components that support research, an administrative core to carry out coordination, management and governance of program components, an evaluative component to ensure programmatic and border health objectives are achieved, and ultimately the development of new approaches to reduce cancer health disparities in our underrepresented population.