Leadership Center Administration
领导中心管理
基本信息
- 批准号:10363632
- 负责人:
- 金额:$ 272.01万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-03-01 至 2024-02-29
- 项目状态:已结题
- 来源:
- 关键词:AdministratorAdolescenceAdultAffectAllergy to eggsBiological AssayBiological MarkersChildClinicalClinical ProtocolsClinical ResearchClinical TrialsCollaborationsComplexConflict (Psychology)Cost efficiencyData AnalysesData CollectionDevelopmentDiseaseEmergency SituationEnsureEquilibriumFood HypersensitivityFoundationsFundingFunding OpportunitiesGoalsGrantImmune responseImmunologistImmunotherapyImpairmentIndividualInfrastructureInternationalInvestigationLaboratoriesLeadLeadershipLifeMalnutritionMilk HypersensitivityMonitorMorbidity - disease rateNational Institute of Allergy and Infectious DiseaseNut HypersensitivityOccupational activity of managing financesOralPerformancePharmaceutical PreparationsPhasePopulationPositioning AttributePrevalencePreventionPrevention approachPrevention strategyProductivityProtocols documentationPublicationsPublishingQuality of lifeReactionResearchResearch PersonnelResourcesScienceSiteStandardizationStructureTherapeuticTimeTrainingVisionWheat HypersensitivityWood materialWorkWorkloadbasebiobankbiomarker discoveryclinical trial implementationcost efficienteffective therapyexperiencefood allergeninnovationnext generationnoveloperationpatient subsetsprotocol developmentsoundsurveillance study
项目摘要
Summary
Food allergy research has increased dramatically over the past 15 years providing us with potential therapeutic
and prevention strategies. The overarching goal of the research agenda proposed in this application is to position
CoFAR as the international leader in the study of food allergy, including optimal characterization of the disease
and development of the next generation of treatments. The research agenda will be based first and foremost on
the best possible science, but to maximize productivity we will also need to plan judiciously so that all available
resources can be used to their utmost capacity. Therefore, the research agenda will need to carefully select and
stage protocols based not just on their potential to advance the field, but also with careful consideration regarding
other novel treatments that may be under development, and how one study may inform the next. Finally, the
overall research strategy will also need to balance the work load of the SACCC and each CRU in the consortium.
This overall agenda will be accomplished through the following major components: 1) To implement a leadership
team capable of providing optimal administration of the Consortium, including financial, operational, and
managerial aspects, as well as protocol development and implementation, data collection and analysis, and
publications and presentations, with judicious financial management. Dr. Robert Wood will lead this team, with
co-PIs Drs. Wesley Burks and Marsha Wills-Karp, who will lead the Biomarker Facility and Opportunity Fund,
respectively. The team will also include a financial administrator as well as a highly experienced grants
management group at Johns Hopkins. The leadership team will work closely with the NIAID and SACCC,
together providing day-to-day management of all clinical operations within the consortium. 2) To develop the
necessary committee structure to guide and implement the Consortium’s administrative and clinical operations.
3) To develop a structure of financial management that will make optimal use of all CoFAR funds and resources.
4) To integrate the Biomarker Facility into each clinical protocol. 4) To maximally leverage the resources and
potential of the Opportunity Fund to expand the mechanistic study of food allergy and its treatment.
It is anticipated that a minimum of 3 protocols, including both clinical trials and non-interventional studies, will be
initiated and completed over the seven-year funding period, and this could rise to 5 or even 6 protocols depending
on the size, duration, and complexity of each study. If successful, this research agenda will define not just the
next 7 years of CoFAR, but will also establish the platform for the next decade(s) of food allergy research.
总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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ROBERT A WOOD其他文献
ROBERT A WOOD的其他文献
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{{ truncateString('ROBERT A WOOD', 18)}}的其他基金
Treatment of Peanut Allergy with Intradermal Administration of ASP0892 (ARA-LAMP-vax): A Randomized, Double-Blind, Placebo-Controlled, Phase I/II Study
皮内注射 ASP0892 (ARA-LAMP-vax) 治疗花生过敏:一项随机、双盲、安慰剂对照的 I/II 期研究
- 批准号:
10363633 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
Clinical Research Unit: Johns Hopkins University
临床研究单位:约翰霍普金斯大学
- 批准号:
9307452 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
Treatment of Peanut Allergy with Intradermal Administration of ASP0892 (ARA-LAMP-vax): A Randomized, Double-Blind, Placebo-Controlled, Phase I/II Study
皮内注射 ASP0892 (ARA-LAMP-vax) 治疗花生过敏:一项随机、双盲、安慰剂对照的 I/II 期研究
- 批准号:
10664077 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
Treatment of Peanut Allergy with Intradermal Administration of ASP0892 (ARA-LAMP-vax): A Randomized, Double-Blind, Placebo-Controlled, Phase I/II Study
皮内注射 ASP0892 (ARA-LAMP-vax) 治疗花生过敏:一项随机、双盲、安慰剂对照的 I/II 期研究
- 批准号:
10581630 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
Treatment of Peanut Allergy with Intradermal Administration of ASP0892 (ARA-LAMP-vax): A Randomized, Double-Blind, Placebo-Controlled, Phase I/II Study
皮内注射 ASP0892 (ARA-LAMP-vax) 治疗花生过敏:一项随机、双盲、安慰剂对照的 I/II 期研究
- 批准号:
10398332 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
Clinical Research Unit: Johns Hopkins University
临床研究单位:约翰霍普金斯大学
- 批准号:
10378487 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
Clinical Research Unit: Johns Hopkins University
临床研究单位:约翰霍普金斯大学
- 批准号:
10580033 - 财政年份:2017
- 资助金额:
$ 272.01万 - 项目类别:
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