Integrative Training in Neural Interfacing

神经接口综合培训

• 批准号: 10204598
• 负责人: BIN HE
• 金额: $ 19.81万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10204598
• 关键词: Training; relating to nervous system

Project Summary We propose to establish an integrative graduate training program in Neural Interfacing to enhance significantly the depth and breadth of interdisciplinary education and training of the next generation of scientific and technical leaders in this important, emerging field. The proposed program is motivated by the notion that future breakthroughs in neural interfacing research will be made by engineers who innovate neural interfacing technologies with a deep understanding of the fundamental issues and principles of brain science, and who have had hands-on experience in the application of neural interfacing technology in a real-world biological setting, aiming at ultimate clinical applications. The proposed program will train doctoral students with quantitative engineering backgrounds to: 1) Develop the technological and theoretical foundations to understand brain function and dysfunction through neural interfacing, i.e., through sensing, modeling, decoding, and modulating brain dynamics at circuit, network, and whole brain levels, 2) Advance our understanding of brain function in the domains of learning, motor control, perception and cognition, and determine and quantify the adaptive changes of the brain that occur in a novel environment, when interacting with a machine, or when in an altered, diseased state, and 3) Innovate brain sensing, modeling, decoding, and modulation technologies, based both on quantifiable behavioral or perceptual outcomes and on the adaptive changes occurring in the brain during a neural intervention. Our predoctoral fellows will be trained through an array of mechanisms including a newly proposed Neuroengineering Minor, a Practicum of Neural Interfacing course consisting of 8~12 mini-lab-rotations, in-depth research rotations, thesis co-advisors, weekly training activities including seminars and colloquia, and training in career skills development and responsible conduct of research. An advisory system will help guide students through the program. Our program will lower the barriers to interdisciplinary, convergent research by training students with quantitative backgrounds to possess integrative expertise in multiple fields so that, going forward, these students can serve as catalysts for the cross-fertilization of engineering with neuroscience in the next generation. Our trainees will be well prepared for academic and industrial challenges, be competitive candidates for academic, industry and government careers, and be at the forefront of translating scientific findings and engineering and computational technology development into industrial and clinical settings. It is anticipated that trainees of the proposed training program will become future leaders through neurotechnology innovations that enhance, measure and modulate, and ultimately heal our brain through neural interfaces.

项目概要 我们建议建立一个神经接口综合研究生培训项目，以增强 显着提高跨学科教育和下一代科学人才培训的深度和广度 以及这个重要的新兴领域的技术领导者。拟议计划的动机是 神经接口研究的未来突破将由神经接口创新的工程师来实现 对脑科学的基本问题和原理有深入了解的技术，并且拥有 拥有在现实生物环境中应用神经接口技术的实践经验， 旨在最终临床应用。拟议的计划将培养具有定量能力的博士生 工程背景：1）开发理解大脑的技术和理论基础 通过神经接口，即通过感知、建模、解码和调节来实现功能和功能障碍 电路、网络和全脑水平的大脑动力学，2) 增进我们对大脑功能的理解 学习、运动控制、感知和认知领域，并确定和量化适应性变化 大脑在新的环境中、与机器交互时、或者在改变的、患病的环境中发生的变化 状态，以及3）创新大脑传感、建模、解码和调制技术，基于 可量化的行为或感知结果以及大脑在一段时间内发生的适应性变化 神经干预。我们的博士前研究员将通过一系列机制接受培训，包括新的 提议辅修神经工程，神经接口实习课程，由 8~12 次迷你实验室轮换组成， 深入的研究轮换、论文共同顾问、每周培训活动（包括研讨会和座谈会）以及 职业技能发展和负责任的研究行为培训。咨询系统将有助于指导 学生通过该计划。我们的计划将通过以下方式降低跨学科、融合研究的障碍 培养具有定量背景的学生拥有多个领域的综合专业知识，以便 展望未来，这些学生可以成为工程与神经科学交叉融合的催化剂 下一代。我们的学员将为学术和行业挑战做好充分准备，并具有竞争力 学术、工业和政府职业的候选人，并处于科学翻译的最前沿 研究结果以及工程和计算技术开发到工业和临床环境中。这是 预计拟议培训计划的学员将通过神经技术成为未来的领导者 通过神经接口增强、测量和调节并最终治愈我们的大脑的创新。