Administrative Core
Administrative Core
批准号:
10204118
负责人:
Pamela J Lein
金额:
$27.48万
依托单位国家:
美国
项目类别:
财政年份:
2012
资助国家:
美国
项目状态:
已结题
起止时间:
2012-09-01 至 2023-05-31
关键词:
AcuteAdvanced DevelopmentAdvisory CommitteesAnticonvulsantsCalendarChemicalsCholinesterase InhibitorsCollaborationsCommittee MembersCommunicationCommunitiesDataDatabase Management SystemsDevelopmentEducational workshopEnsureEnvironmental HealthEquipment and supply inventoriesEventFederal GovernmentFosteringFundingGeneral PopulationGoalsGovernment AgenciesGrantHuman ResourcesIACUCIntellectual PropertyIntoxicationInvestigational DrugsIsoflurophateLaboratoriesLeadLeadershipLegal patentLogisticsManuscriptsMedical ResearchMissionMonitorOnline SystemsOrganophosphatesParaoxonPicrotoxinPoliciesProceduresProtocols documentationPubMedReadinessReagentRegulationReportingResearchResearch ActivityResearch InstituteResearch PersonnelResearch Project GrantsResource SharingRoleSafetySecureSecuritySeizuresSeriesSomanStrategic PlanningSystemTechnology TransferTherapeuticTherapeutic AgentsTimeLineTrainingUnited States Food and Drug AdministrationUnited States National Institutes of HealthUniversitiesWorkauthoritycentral databasechemical threatdata exchangedata managementdata sharingeducation researchimprovedinterestmedical countermeasuremeetingsnoveloperationpreventprogramsreceptorresearch and developmentstatisticssuccesssynergismtetramethylenedisulfotetraminetherapeutic developmentweb site
中文摘要
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英文摘要
Project Summary – Administrative Core
The overall goal of the UC Davis CounterACT Center of Excellence is to identify and advance improved medical
countermeasures for stopping seizures and preventing long-term consequences of acute intoxication with
chemical threat agents, specifically organophosphate cholinesterase inhibitors like diisopropylfluorophosphate
(DFP), paraoxon and soman, or GABAA receptor blockers like tetramethylenedisulfotetramine (TETS) and
picrotoxin. The UC Davis CounterACT Center comprises three projects, three scientific cores, a research
education core and multiple committees — all of which must work closely together to ensure success. The role
of the Administrative Core is to oversee and coordinate the scientific and administrative operations of the
Center's activities and to foster interactions and synergism among Center research projects and scientific cores,
ultimately ensuring the Center meets annual milestones established in collaboration with NIH CounterACT
program officer(s). Additionally, the Administrative Core will coordinate interactions with the UC Davis
administration and external entities, such as the NIH CounterACT administration, the Center's External Advisory
Committee, the larger CounterACT research community, the U.S. Food and Drug Administration (FDA), the
Biomedical Advanced Research and Development Authority (BARDA), and commercial partners. The Core's
objectives are: (1) Develop a strategic plan for achieving annual Center milestones and ensure its effective and
efficient implementation; (2) Provide scientific leadership and logistical support to coordinate and integrate
Center activities and promote interactions among Center investigators; (3) Facilitate data and resource sharing
among Center investigators and other CounterACT investigators; (4) Provide budgetary oversight and grant
management; (5) Ensure the safety and security of personnel, materials, data and facilities; (6) Coordinate the
development of intellectual property (IP) strategies and the transitioning of leads for advanced development; (7)
Coordinate with FDA, BARDA and other federal government agencies; and (8) Identify, engage and coordinate
communications with commercial partners.
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会议论文
Administrative Core
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批准号:10684067
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项目类别:
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资助金额:$43.21万
-
财政年份:2022
-
负责人:Pamela J Lein
-
依托单位:
Project 1: Reduction of Pro-Inflammatory Signaling
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批准号:10684082
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项目类别:
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资助金额:$49.11万
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财政年份:2022
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负责人:Pamela J Lein
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依托单位:
Ketogenic diet approaches to slow disease progression in a rat model of Alzheimer's disease
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批准号:9977496
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项目类别:
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资助金额:$43.18万
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财政年份:2020
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负责人:Pamela J Lein
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依托单位:
Identifying Molecular Targets for the Proconvulsant Activity of TETS
-
批准号:9905564
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项目类别:
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资助金额:$18.7万
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财政年份:2019
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负责人:Pamela J Lein
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依托单位:
Does air pollution increase risk of AD in a genetically susceptible animal model?
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批准号:9126737
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项目类别:
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资助金额:$23.54万
-
财政年份:2016
-
负责人:Pamela J Lein
-
依托单位:
Administrative Core
-
批准号:8411734
-
项目类别:
-
资助金额:$18.83万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Mitigation of Neurological Damage Following Seizures
-
批准号:10204125
-
项目类别:
-
资助金额:$101.66万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication
-
批准号:10204117
-
项目类别:
-
资助金额:$364.92万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:9142832
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项目类别:
-
资助金额:$13.0万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8925299
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项目类别:
-
资助金额:$4.1万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8533058
-
项目类别:
-
资助金额:$332.98万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
CounterACT 2020 Annual Meeting
-
批准号:9925004
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项目类别:
-
资助金额:$15.0万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8730727
-
项目类别:
-
资助金额:$327.28万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:9060480
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项目类别:
-
资助金额:$15.47万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8851844
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项目类别:
-
资助金额:$7.71万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8332981
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项目类别:
-
资助金额:$319.22万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Identification of novel therapeutic approaches for TETS and OP intoxication
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批准号:8153115
-
项目类别:
-
资助金额:$38.38万
-
财政年份:2010
-
负责人:Pamela J Lein
-
依托单位:
Identification of novel therapeutic approaches for TETS and OP intoxication
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批准号:8019767
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项目类别:
-
资助金额:$38.28万
-
财政年份:2010
-
负责人:Pamela J Lein
-
依托单位:
Molecular and Cellular Basis of PCB Developmental Neurotoxicity
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批准号:7743503
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项目类别:
-
资助金额:$47.4万
-
财政年份:2008
-
负责人:Pamela J Lein
-
依托单位:
Molecular and Cellular Basis of PCB Developmental Neurotoxicity
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批准号:8197470
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项目类别:
-
资助金额:$45.89万
-
财政年份:2008
-
负责人:Pamela J Lein
-
依托单位:
海外基金