Administrative Core

项目摘要-行政核心

Project Summary – Administrative Core The overall objective of the new UC Davis CounterACT Center of Excellence is to identify and advance the development of therapeutic strategies for mitigating long-term, adverse neurologic consequences in individuals who survive the cholinergic crisis triggered by acute intoxication with organophosphate (OP) cholinesterase inhibitors. The Center is comprised of three scientific Projects, three scientific Cores, a Research Education Core, an Emerging Science and Scientists Pilot Project Program, and multiple committees — all of which will work closely together to ensure success. The Administrative Core will centralize coordination, communication and integration among the Projects and Cores and foster synergy across the Center, ultimately ensuring the Center meets annual milestones established in collaboration with NIH CounterACT program officer(s). Activities will include providing overall scientific leadership, fiscal oversight, and logistical support as well as assistance with disseminating research findings and encouraging and facilitating data sharing with external investigators. Additionally, the Administrative Core will coordinate Center interactions with the UC Davis administration and external entities, such as the NIH CounterACT administration, the Center’s External Advisory Board, the larger CounterACT research community, the U.S. Food and Drug Administration (FDA), the Biomedical Advanced Research and Development Authority (BARDA), and potential commercial partners. The Core’s objectives are to: (1) Provide scientific leadership and logistics support to coordinate and integrate Center activities and promote interactions among Center investigators to meet annual Center milestones; (2) Administer the Emerging Science and Scientists Pilot Project Program (ESSP3); (3) Facilitate data and resource sharing among Center investigators and other CounterACT investigators; (4) Provide budgetary oversight and grant management; (5) Ensure the safety and security of personnel, materials, data and facilities; (6) Pursue intellectual property (IP) strategies, and identify, engage and coordinate communications with commercial partners; and (7) Coordinate with FDA, BARDA and other federal government agencies.