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Administrative Core

行政核心

基本信息

批准号：
10684067
负责人：
Pamela J Lein
金额：
$ 43.21万
依托单位：
UNIVERSITY OF CALIFORNIA AT DAVIS
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-01 至 2027-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10684067
关键词：
Acute Administrator Advanced Development Analytical Chemistry Authorization documentation Award Calendar Chemicals Cholinesterase Inhibitors Chronic Collaborations Communication Communities Data Database Management Systems Educational workshop Ensure Environmental Health Equipment and supply inventories Event Federal Government Fostering Funding General Population Goals Government Agencies Grant Hazardous Substances Human Resources IACUC Individual Intellectual Property Intoxication Investigational Drugs Leadership Legal patent Logistics Manuscripts Medical Research Mission Monitor Neurologic Online Systems Organophosphates Outcome Pharmaceutical Chemistry Pilot Projects Policies Procedures PubMed Publications Qualifying Readiness Reagent Regulation Reporting Research Research Institute Research Personnel Research Project Grants Resource Sharing Safety Science Scientist Secure Security Strategic Planning System Technology Transfer Therapeutic Therapeutic Agents Training United States Food and Drug Administration United States National Institutes of Health Universities Work authority central database chemical threat cholinergic data sharing education research innovation interest medical countermeasure meetings member operation pre-Investigational New Drug meeting programs recruit research and development success synergism therapeutic candidate therapeutic development timeline web site

项目摘要

Project Summary – Administrative Core The overall objective of the new UC Davis CounterACT Center of Excellence is to identify and advance the development of therapeutic strategies for mitigating long-term, adverse neurologic consequences in individuals who survive the cholinergic crisis triggered by acute intoxication with organophosphate (OP) cholinesterase inhibitors. The Center is comprised of three scientific Projects, three scientific Cores, a Research Education Core, an Emerging Science and Scientists Pilot Project Program, and multiple committees — all of which will work closely together to ensure success. The Administrative Core will centralize coordination, communication and integration among the Projects and Cores and foster synergy across the Center, ultimately ensuring the Center meets annual milestones established in collaboration with NIH CounterACT program officer(s). Activities will include providing overall scientific leadership, fiscal oversight, and logistical support as well as assistance with disseminating research findings and encouraging and facilitating data sharing with external investigators. Additionally, the Administrative Core will coordinate Center interactions with the UC Davis administration and external entities, such as the NIH CounterACT administration, the Center’s External Advisory Board, the larger CounterACT research community, the U.S. Food and Drug Administration (FDA), the Biomedical Advanced Research and Development Authority (BARDA), and potential commercial partners. The Core’s objectives are to: (1) Provide scientific leadership and logistics support to coordinate and integrate Center activities and promote interactions among Center investigators to meet annual Center milestones; (2) Administer the Emerging Science and Scientists Pilot Project Program (ESSP3); (3) Facilitate data and resource sharing among Center investigators and other CounterACT investigators; (4) Provide budgetary oversight and grant management; (5) Ensure the safety and security of personnel, materials, data and facilities; (6) Pursue intellectual property (IP) strategies, and identify, engage and coordinate communications with commercial partners; and (7) Coordinate with FDA, BARDA and other federal government agencies.

项目摘要-行政核心