Administrative Core
Administrative Core
批准号:
10684067
负责人:
Pamela J Lein
金额:
$43.21万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-09-01 至 2027-08-31
关键词:
AcuteAdministratorAdvanced DevelopmentAnalytical ChemistryAuthorization documentationAwardCalendarChemicalsCholinesterase InhibitorsChronicCollaborationsCommunicationCommunitiesDataDatabase Management SystemsEducational workshopEnsureEnvironmental HealthEquipment and supply inventoriesEventFederal GovernmentFosteringFundingGeneral PopulationGoalsGovernment AgenciesGrantHazardous SubstancesHuman ResourcesIACUCIndividualIntellectual PropertyIntoxicationInvestigational DrugsLeadershipLegal patentLogisticsManuscriptsMedical ResearchMissionMonitorNeurologicOnline SystemsOrganophosphatesOutcomePharmaceutical ChemistryPilot ProjectsPoliciesProceduresPubMedPublicationsQualifyingReadinessReagentRegulationReportingResearchResearch InstituteResearch PersonnelResearch Project GrantsResource SharingSafetyScienceScientistSecureSecurityStrategic PlanningSystemTechnology TransferTherapeuticTherapeutic AgentsTrainingUnited States Food and Drug AdministrationUnited States National Institutes of HealthUniversitiesWorkauthoritycentral databasechemical threatcholinergicdata sharingeducation researchinnovationinterestmedical countermeasuremeetingsmemberoperationpre-Investigational New Drug meetingprogramsrecruitresearch and developmentsuccesssynergismtherapeutic candidatetherapeutic developmenttimelineweb site
中文摘要
项目摘要-行政核心
英文摘要
Project Summary – Administrative Core
The overall objective of the new UC Davis CounterACT Center of Excellence is to identify and advance the
development of therapeutic strategies for mitigating long-term, adverse neurologic consequences in individuals
who survive the cholinergic crisis triggered by acute intoxication with organophosphate (OP) cholinesterase
inhibitors. The Center is comprised of three scientific Projects, three scientific Cores, a Research Education
Core, an Emerging Science and Scientists Pilot Project Program, and multiple committees — all of which will
work closely together to ensure success. The Administrative Core will centralize coordination, communication
and integration among the Projects and Cores and foster synergy across the Center, ultimately ensuring the
Center meets annual milestones established in collaboration with NIH CounterACT program officer(s). Activities
will include providing overall scientific leadership, fiscal oversight, and logistical support as well as assistance
with disseminating research findings and encouraging and facilitating data sharing with external investigators.
Additionally, the Administrative Core will coordinate Center interactions with the UC Davis administration and
external entities, such as the NIH CounterACT administration, the Center’s External Advisory Board, the larger
CounterACT research community, the U.S. Food and Drug Administration (FDA), the Biomedical Advanced
Research and Development Authority (BARDA), and potential commercial partners. The Core’s objectives are
to: (1) Provide scientific leadership and logistics support to coordinate and integrate Center activities and
promote interactions among Center investigators to meet annual Center milestones; (2) Administer the Emerging
Science and Scientists Pilot Project Program (ESSP3); (3) Facilitate data and resource sharing among Center
investigators and other CounterACT investigators; (4) Provide budgetary oversight and grant management; (5)
Ensure the safety and security of personnel, materials, data and facilities; (6) Pursue intellectual property (IP)
strategies, and identify, engage and coordinate communications with commercial partners; and (7) Coordinate
with FDA, BARDA and other federal government agencies.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Project 1: Reduction of Pro-Inflammatory Signaling
-
批准号:10684082
-
项目类别:
-
资助金额:$49.11万
-
财政年份:2022
-
负责人:Pamela J Lein
-
依托单位:
Ketogenic diet approaches to slow disease progression in a rat model of Alzheimer's disease
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批准号:9977496
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项目类别:
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资助金额:$43.18万
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财政年份:2020
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负责人:Pamela J Lein
-
依托单位:
Identifying Molecular Targets for the Proconvulsant Activity of TETS
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批准号:9905564
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项目类别:
-
资助金额:$18.7万
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财政年份:2019
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负责人:Pamela J Lein
-
依托单位:
Does air pollution increase risk of AD in a genetically susceptible animal model?
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批准号:9126737
-
项目类别:
-
资助金额:$23.54万
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财政年份:2016
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负责人:Pamela J Lein
-
依托单位:
Administrative Core
-
批准号:10204118
-
项目类别:
-
资助金额:$27.48万
-
财政年份:2012
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负责人:Pamela J Lein
-
依托单位:
Administrative Core
-
批准号:8411734
-
项目类别:
-
资助金额:$18.83万
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财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Mitigation of Neurological Damage Following Seizures
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批准号:10204125
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项目类别:
-
资助金额:$101.66万
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财政年份:2012
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负责人:Pamela J Lein
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依托单位:
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication
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批准号:10204117
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项目类别:
-
资助金额:$364.92万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:9142832
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项目类别:
-
资助金额:$13.0万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8925299
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项目类别:
-
资助金额:$4.1万
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财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8533058
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项目类别:
-
资助金额:$332.98万
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财政年份:2012
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负责人:Pamela J Lein
-
依托单位:
CounterACT 2020 Annual Meeting
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批准号:9925004
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项目类别:
-
资助金额:$15.0万
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财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:8730727
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项目类别:
-
资助金额:$327.28万
-
财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
-
批准号:9060480
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项目类别:
-
资助金额:$15.47万
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财政年份:2012
-
负责人:Pamela J Lein
-
依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
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批准号:8851844
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项目类别:
-
资助金额:$7.71万
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财政年份:2012
-
负责人:Pamela J Lein
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依托单位:
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication
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批准号:8332981
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项目类别:
-
资助金额:$319.22万
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财政年份:2012
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负责人:Pamela J Lein
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依托单位:
Identification of novel therapeutic approaches for TETS and OP intoxication
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批准号:8153115
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项目类别:
-
资助金额:$38.38万
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财政年份:2010
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负责人:Pamela J Lein
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依托单位:
Identification of novel therapeutic approaches for TETS and OP intoxication
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批准号:8019767
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项目类别:
-
资助金额:$38.28万
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财政年份:2010
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负责人:Pamela J Lein
-
依托单位:
Molecular and Cellular Basis of PCB Developmental Neurotoxicity
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批准号:7743503
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项目类别:
-
资助金额:$47.4万
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财政年份:2008
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负责人:Pamela J Lein
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依托单位:
Molecular and Cellular Basis of PCB Developmental Neurotoxicity
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批准号:8197470
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项目类别:
-
资助金额:$45.89万
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财政年份:2008
-
负责人:Pamela J Lein
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依托单位:
海外基金