Administrative Core 1

行政核心1

• 批准号: 10208805
• 负责人: PATRICK HWU
• 金额: $ 22.85万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10208805
• 关键词: Advocate; Appointment; Award; Bioinformatics; Biometry; Clinical; Clinical Trials; Communication; Consensus; Consultations; Data Commons; Development; Discipline; Disease; Ensure; Funding; Goals; Government; Leadership; Maintenance; Mentors; Minority; Monitor; Patient Care; Patients; Peer Review; Policies; Preparation; Process; Publications; Quality Control; Regulation; Reporting; Research; Research Personnel; Resources; Role; Schedule; Scientist; Site; Skin Cancer; Time; United States National Institutes of Health; University of Texas M D Anderson Cancer Center; Woman; career; data quality; data repository; data sharing; data standards; experience; flexibility; interdisciplinary approach; lectures; meetings; melanoma; programs; quality assurance; recruit; symposium

Adminstrative Core 1: Project Summary/Abstract Within the SPORE framework, the Administrative Core (Core 1) will be responsible for incorporating the diverse scientific disciplines of the SPORE investigators into a highly integrated, interdisciplinary approach focused on achieving excellence in translational melanoma research towards a significant impact on the care of patients battling this disease. The primary goal of this group is to assure the successful continued oversight and coordination of all projects, cores, and developmental and career enhancement programs through expert guidance in fiscal management, centralized communication, and general administration for all activities. This core will be led by three outstanding scientists and well-established mentors who currently hold high-level administrative, research, and/or clinical appointments at MD Anderson and possess decades of combined leadership experience: Drs. Patrick Hwu, Elizabeth Grimm, and Jeffrey E. Lee. Specific responsibilities of the Administrative Core include the following: · Compliance with all institutional, federal, and NIH/NCI regulations and requirements. · Communication and consultation with the NCI project officer and other NCI staff, including preparation of all required reports, publications, and other requested communications. · Monitoring data quality control and assurance activities in conjunction with the Biostatistics and Bioinformatics Core (Core 3). · Optimization of clinical trial efforts, including monitoring and enhancing accrual progress of related SPORE clinical trials, through the Clinical Trials Management Resource (co-directed by Dr. Hwu and Lee) housed within this Administrative Core. · Maintenance of fiscal and budgetary responsibilities, including implementing the SPORE flexibility option as appropriate through ongoing assessments of program progress and justifications for funding allocations/reallocations. · Convening all necessary meetings, including the Executive Committee, Internal and External Advisory Boards (IAB/EAB), scientific meetings, research meetings, lectures, and symposia, including scheduling, development and distribution of meeting materials, and recording minutes as appropriate. · Coordination and funding of Patient Advocate activities. · Establishment and monitoring of policies for recruitment and retention of women and minorities in this program. · Coordination with other SPORE sites to initiate and enhance collaborative research efforts, co- sponsor a yearly Skin Cancer conference, and pursue opportunities for high potential Developmental Research Program (DRP) and Career Enhancement Program (CEP) applications from collaborating investigators.

管理核心 1：项目摘要/摘要 在 SPORE 框架内，管理核心（核心 1）将负责纳入 SPORE 研究人员的不同科学学科融入高度集成的跨学科方法 专注于在转化黑色素瘤研究中取得卓越成就，对护理产生重大影响 与这种疾病作斗争的患者。该小组的主要目标是确保成功的持续监督 通过专家协调所有项目、核心以及发展和职业提升计划 对所有活动的财务管理、集中沟通和一般管理的指导。这 核心将由三位杰出科学家和目前担任高水平的知名导师领导 在 MD 安德森担任行政、研究和/或临床职务，并拥有数十年的综合经验 领导经验：博士。帕特里克·胡、伊丽莎白·格林和杰弗里·E·李。 行政核心的具体职责包括： · 遵守所有机构、联邦和 NIH/NCI 法规和要求。 · 与NCI项目官员和其他NCI工作人员的沟通和咨询，包括准备工作 所有必需的报告、出版物和其他要求的通讯。 · 与生物统计学和生物统计学相结合监测数据质量控制和保证活动 生物信息学核心（核心 3）。 · 优化临床试验工作，包括监测和加强相关的应计进展 SPORE 临床试验，通过临床试验管理资源（由 Hwu 博士和 Lee）位于该行政核心内。 · 维持财政和预算责任，包括实施 SPORE 灵活性 通过对方案进展和供资理由的持续评估酌情选择 分配/重新分配。 · 召开所有必要的会议，包括执行委员会、内部和外部咨询会议 委员会 (IAB/EAB)、科学会议、研究会议、讲座和研讨会，包括 安排、制定和分发会议材料，并酌情记录会议记录。 · 患者倡导者活动的协调和资助。 · 制定并监督该领域招募和留用妇女和少数民族的政策 程序。 · 与其他 SPORE 站点协调，发起和加强合作研究工作，共同 赞助每年一度的皮肤癌会议，并寻求高潜力发展机会 研究计划 (DRP) 和职业提升计划 (CEP) 申请 合作调查人员。