MGNet Pilot Studies Program

MGNet 试点研究计划

• 批准号: 10207814
• 负责人: Linda Louise Kusner
• 金额: $ 10.02万
• 依托单位: GEORGE WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10207814
• 关键词: Address; Americas; Applications Grants; Awareness; Basic Science; Biometry; Cholinergic Receptors; Clinical Data; Clinical Research; Clinical Trials; Collaborations; Collection; Communities; Coupled; Development; Discipline; Fc Receptor; Foundations; Funding; Goals; Grant; Immunology; Investigation; MUSK gene; Myasthenia Gravis; Outcome Measure; Patient advocacy; Patient-Focused Outcomes; Peer Review; Pilot Projects; Process; Rare Diseases; Request for Applications; Research; Research Personnel; Research Project Grants; Research Support; Resources; Science; Services; Specimen; Thymoma; Training; biobank; biomarker discovery; biomarker validation; career; clinical phenotype; clinical trial readiness; early onset; improved; innovation; meetings; predictive marker; profession allied to medicine; programs; research and development

The primary purpose of the MGNet pilot study program is to promote development of highly innovative early stage investigations focused on discovery of biomarkers predictive of treatment, improve clinical trial readiness through enhancement of patient-centered outcome measures, or process improvement of clinical trials in myasthenia gravis (MG). The MGNet RDCRC will more precisely define the clinical phenotype of MG subtypes (thymoma-associated, acetylcholine receptor antibody-positive of late- and early-onset, muscle-specific kinase-positive, ACHR- MUSK negative) coupled with biospecimen collection. This rich resource will be available for pilot grant proposals with grant recipients benefiting from MGNet core services in clinical research coordinator training, immunology, and biostatistics. Investigators will also actively collaborate with MGNet administration and investigators to assure successful completion of study milestones. MGNet will request applications on an annual basis and only select the most promising proposals that fulfill MGNet goals. The pilot study program benefits greatly from the collaboration of the MG Foundation of America and Conquer MG, which have agreed to fold in their existing pilot grant programs into the MGNet RDCRC.

MGNet试点研究计划的主要目的是促进高等教育的发展