Core 2: Methodology

核心 2：方法论

• 批准号: 10208838
• 负责人: Sean M. Murphy
• 金额: $ 24.04万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10208838
• 关键词: Accounting; Address; Adoption; Applications Grants; Area; Caring; Chronic Disease; Clinical; Collaborations; Communities; Consultations; Cost Savings; Cost-Benefit Analysis; Costs and Benefits; Data; Data Set; Development; Disease; Doctor of Philosophy; Economic Policy; Economics; Effectiveness; Ensure; Equilibrium; Evaluation Methodology; Evidence based practice; Evidence based treatment; Goals; HIV; HIV/HCV; Health; Health Services Research; Hepatitis C virus; Individual; Interdisciplinary Study; Intervention; Life Expectancy; Link; Measures; Methodology; Methods; Modeling; Outcome; Outcomes Research; Play; Policies; Policy Maker; Population; Procedures; Productivity; Protocols documentation; Provider; Qualifying; Quality of life; Records; Recovery; Research; Research Personnel; Research Support; Resource Allocation; Resources; Role; Schools; Services; Substance Use Disorder; System; Time; Treatment Cost; Update; Work; adaptive intervention; budget impact; comparison intervention; cost; cost effectiveness; cost outcomes; design; economic evaluation; economic impact; evidence base; health economics; implementation framework; implementation intervention; implementation research; improved; individual patient; intervention cost; multidisciplinary; novel strategies; online community; programs; sound; stakeholder perspectives; substance use; substance use treatment; therapy development; tool; treatment program; uptake

PROJECT SUMMARY: Methodology Core This Core focuses on economic evaluation approaches, tools, and measures to support new and existing interdisciplinary research collaborations. Despite decades of research supporting a chronic disease approach to substance use disorder treatment and recovery, uptake and sustainment remain low. Some of the most important factors inhibiting adoption of evidence-based practices are concerns about the potential burden on staff and other resources, as well as overall budget impact. Changing current practices requires not only clinical evidence, but also consideration of additional costs and the reallocation of existing resources that will result from the changes. Economic analysis can directly address these issues by providing a detailed accounting of the costs to the provider of updating services, and more broadly inform “real-world” resource allocation decisions by providing policymakers and payers with evidence on the net economic and health impact of new approaches and their fiscal viability over time. This requires considering both costs and consequences of a new intervention, often using a cost-effectiveness or cost-benefit analysis framework. The overall aim of CHERISH (Center for Health Economics of Treatment Interventions for Substance Use Disorder, HCV, and HIV) is to develop and disseminate economic evidence that informs substance use disorder policy and HCV and HIV care of people who use substances. In this renewal period we will expand our focus to outcome and implementation research that is conducted at the individual, system, and community levels with the following specific aims: 1) to guide researchers in the design, implementation, and interpretation of economic analyses of treatment for substance use disorder, and HCV and HIV among people who use substances, and 2) to develop and apply methods that support economic evaluations for substance use disorder, and HCV and HIV among people who use substances with a focus on intervention implementation and adaptive interventions. Through the CHERISH Consultation Service and Research Affiliates Program, we will contribute to the development of new grant proposals with explicit economic aims, and will continue to connect with and advise qualifying researchers nationally to ensure that planned economic analyses are methodologically sound and feasible. We will expand the CHERISH Research Affiliates program so it can serve as a nationally-representative virtual community for researchers engaged in substance use disorder treatment health economic research. Working with existing studies and integrating data from third-party datasets and administrative records, we will develop analytic frameworks and tools for evaluating individual and systems-level substance use disorder and related implementation interventions. We will also develop economic evaluation methods for adaptive interventions. In collaboration with the Population Data & Modeling Core, we will assist researchers in using external data to enhance interpretation of economic evaluation results.

项目摘要：方法论核心 该核心专注于经济评估方法，工具和措施，以支持新的和现有 跨学科研究合作。尽管有数十年的研究支持慢性疾病方法 对于药物使用障碍的治疗和恢复，吸收和维持仍然很低。其中一些 抑制基于证据的实践的重要因素是对潜在伯恩的关注 员工和其他资源以及总体预算影响。改变当前的做法不仅需要 临床证据，同时也考虑额外成本以及现有资源的重新分配 变化导致。经济分析可以通过提供详细的信息直接解决这些问题 对更新服务提供商的成本进行核算，并更广泛地为“现实世界”资源提供信息 通过为政策制定者和付款人提供有关净经济和健康的证据，分配决策 随着时间的推移，新方法及其财政生存能力的影响。这需要考虑两者的成本和 新干预的后果，通常使用成本效益或成本效益分析框架。这 珍爱的总体目的（卫生经济学中心的治疗干预措施用于药物使用障碍， HCV和HIV）将开发和传播经济证据，以告知药物使用障碍政策 以及使用物质的人的HCV和HIV护理。在这个续签时期，我们将把重点扩展到 在个人，系统和社区层面进行的结果和实施研究 以下具体目的：1）指导研究人员的设计，实施和解释 对使用物质使用障碍治疗的经济分析，以及使用的人的HCV和HIV 物质，以及2）开发和应用支持用于物质使用经济评估的方法 使用以干预实施为重点的物质的人中的疾病，HCV和HIV 和自适应干预措施。通过珍贵的咨询服务和研究分支机构计划，我们 将有助于以明确的经济目标的发展新的赠款提案，并将继续 在全国范围内与合格的研究人员建立联系并提供建议，以确保计划的经济分析是 从方法上讲是合理的，可行的。我们将扩大珍贵的研究分支机构计划，以便它可以 作为一个从事药物使用障碍的研究人员的全国代表性虚拟社区 治疗健康经济研究。与现有研究合作并整合来自第三方的数据 数据集和管理记录，我们将开发用于评估个人的分析框架和工具 以及系统级药物使用障碍和相关的实施干预措施。我们还将发展 自适应干预措施的经济评估方法。与人口数据和建模合作 核心，我们将协助研究人员使用外部数据来增强对经济评估的解释 结果。