Core 2: Methodology

项目摘要：方法核心 该核心侧重于经济评估方法、工具和措施，以支持新的和现有的 跨学科研究合作。尽管几十年的研究支持慢性病的方法 对于物质使用障碍的治疗和康复，摄取和维持水平仍然很低。其中一些最重要的 阻碍采用循证实践的重要因素是对潜在负担的担忧 工作人员和其他资源，以及总体预算影响。改变当前的做法不仅需要 临床证据，但也考虑到额外的成本和重新分配现有资源，这将 是这些变化的结果。经济分析可以通过提供详细的 对更新服务提供商的成本进行核算，并更广泛地向“现实世界”资源提供信息 通过向政策制定者和支付者提供关于净经济和健康的证据来做出分配决策 随着时间的推移，新方法及其财政可行性的影响。这需要同时考虑成本和 新干预措施的后果，通常使用成本效益或成本效益分析框架。这个 药物使用障碍治疗干预健康经济学中心， 丙型肝炎病毒和艾滋病毒)是开发和传播经济证据，为物质使用障碍政策提供信息 以及对吸毒者的丙型肝炎病毒和艾滋病病毒的护理。在此续期期间，我们将把重点扩大到 在个人、系统和社区级别进行的成果和实施研究 以下具体目标：1)指导研究人员设计、实施和解释 吸毒者治疗药物使用障碍、丙型肝炎病毒和艾滋病的经济学分析 2)开发和应用支持物质使用经济评价的方法 以干预实施为重点的药物使用人群中的精神障碍和丙型肝炎病毒和艾滋病毒 和适应性干预。通过珍视咨询服务和研究附属公司计划，我们 将有助于制定具有明确经济目标的新赠款提案，并将继续 与全国合格的研究人员联系并提供建议，以确保计划中的经济分析 在方法上是合理和可行的。我们将扩大珍爱研究附属公司计划，以便它能够 为从事药物使用障碍的研究人员提供具有全国代表性的虚拟社区 医疗卫生经济研究。使用现有研究并集成来自第三方的数据 数据集和行政记录，我们将开发分析框架和工具来评估个人 以及系统一级的药物使用障碍和相关的实施干预措施。我们还将发展 适应性干预的经济评价方法。与人口数据和建模合作 核心，我们将协助研究人员使用外部数据来增强对经济评估的解释 结果。

PROJECT SUMMARY: Methodology Core This Core focuses on economic evaluation approaches, tools, and measures to support new and existing interdisciplinary research collaborations. Despite decades of research supporting a chronic disease approach to substance use disorder treatment and recovery, uptake and sustainment remain low. Some of the most important factors inhibiting adoption of evidence-based practices are concerns about the potential burden on staff and other resources, as well as overall budget impact. Changing current practices requires not only clinical evidence, but also consideration of additional costs and the reallocation of existing resources that will result from the changes. Economic analysis can directly address these issues by providing a detailed accounting of the costs to the provider of updating services, and more broadly inform “real-world” resource allocation decisions by providing policymakers and payers with evidence on the net economic and health impact of new approaches and their fiscal viability over time. This requires considering both costs and consequences of a new intervention, often using a cost-effectiveness or cost-benefit analysis framework. The overall aim of CHERISH (Center for Health Economics of Treatment Interventions for Substance Use Disorder, HCV, and HIV) is to develop and disseminate economic evidence that informs substance use disorder policy and HCV and HIV care of people who use substances. In this renewal period we will expand our focus to outcome and implementation research that is conducted at the individual, system, and community levels with the following specific aims: 1) to guide researchers in the design, implementation, and interpretation of economic analyses of treatment for substance use disorder, and HCV and HIV among people who use substances, and 2) to develop and apply methods that support economic evaluations for substance use disorder, and HCV and HIV among people who use substances with a focus on intervention implementation and adaptive interventions. Through the CHERISH Consultation Service and Research Affiliates Program, we will contribute to the development of new grant proposals with explicit economic aims, and will continue to connect with and advise qualifying researchers nationally to ensure that planned economic analyses are methodologically sound and feasible. We will expand the CHERISH Research Affiliates program so it can serve as a nationally-representative virtual community for researchers engaged in substance use disorder treatment health economic research. Working with existing studies and integrating data from third-party datasets and administrative records, we will develop analytic frameworks and tools for evaluating individual and systems-level substance use disorder and related implementation interventions. We will also develop economic evaluation methods for adaptive interventions. In collaboration with the Population Data & Modeling Core, we will assist researchers in using external data to enhance interpretation of economic evaluation results.