Responsible Conduct of Research Training in Biomedical Data Science for Dental, Oral and Craniofacial Research

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PROJECT SUMMARY/ABSTRACT This R25 educational project proposes to develop a set of training modules for starting oral biology research fellows and dental specialty residents. The proposed modules will introduce the training in Responsible Conduct of Research focusing on biomedical data science in the field of dental, oral and craniofacial research. With the advent of the rapid development of research technologies, the past decade has seen vast accumulation of acquired data on human health and diseases. The biomedical data science is a new research discipline to best analyze the massive biomedical data sets to discover new knowledge about the function and mechanism of our health and disease, which is highly relevant to our future professionals in scientific research and clinical dentistry. Specific challenges in biomedical data science include the appropriate data curation system handling the datasets in a FAIR (Findable, Accessible, Interoperable, and Reusable) manner; the standardized scientific workflow systems to capture the provenance of data transformations; and the ethical challenge in dentistry for privacy, anonymity, security and informed consent using digital, electronic and mobile health records. The proposed educational modules will discuss these challenges in real life scenarios through an extended massive online course (xMOOC) format. Aim 1: The PD/PI will form the WORKING TEAM of committed faculty to [1] curate a bank of highly relevant case series with content advisors who are established in dental, oral and craniofacial research as well as biomedical data science; [2] design and develop case studies and problem sets; and [3] construct video clips with UCLA Instructional Media Production. Aim 2: The PD/PI and the WORKING TEAM will [1] establish the 5-module xMOOC training program; [2] develop forums and case discussion programs; and establish self- test problems. UCLA Center for Advancement of Teaching (CAT) is the campus resources assisting this process. Aim 3: The PD/PI and the WORKING TEAM will [1] initiate the pilot test with invited trainees; and [2] analyze the evaluation matrix and make necessary revisions. To succeed the development of the training module, the PD/PI and the WORKING TEAM will be supported by the educational program advisors and the content advisors solicited throughout from the rich research environment of UCLA. The Dean of UCLA School of Dentistry is committed to support this program development. Finally, the final version of the training module will be professionally evaluated by UCLA Center for the Advancement of Teaching, and disseminated through a non-profit MOOC provider and submitted to NIGMS.