Responsible Conduct of Research Training in Biomedical Data Science for Dental, Oral and Craniofacial Research

负责任地开展牙科、口腔和颅面研究生物医学数据科学研究培训

• 批准号: 10379291
• 负责人: ICHIRO NISHIMURA
• 金额: $ 9.78万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10379291
• 关键词: Address; Back; Case Series; Case Study; Certification; Clinical; Clip; Communities; Consult; Cues; Data; Data Provenance; Data Set; Dental; Dental Specialties; Dentistry; Development; Discipline; Disease; Educational process of instructing; Effectiveness; Environment; Ethics; Evaluation; FAIR principles; Faculty; Future; Goals; Health; Human; Individual; Informed Consent; Instruction; Interview; Knowledge; Learning; Learning Module; Licensing; Life; National Institute of General Medical Sciences; Oral; Privacy; Problem Sets; Process; Production; Program Development; Provider; Research; Research Training; Resources; Running; School Dentistry; Scientist; Security; Self Assessment; Specific qualifier value; Standardization; Surveys; System; Testing; Training; Training Activity; Training Programs; United States National Institutes of Health; Visual; Work; biomedical data science; craniofacial; data curation; design; digital; effectiveness evaluation; flexibility; graduate student; health record; improved; learning network; mHealth; massive open online courses; member; memory process; online course; oral biology; pilot test; programmed cell death protein 1; programs; responsible research conduct; self testing; skills; technology research and development; theories; work-study

PROJECT SUMMARY/ABSTRACT This R25 educational project proposes to develop a set of training modules for starting oral biology research fellows and dental specialty residents. The proposed modules will introduce the training in Responsible Conduct of Research focusing on biomedical data science in the field of dental, oral and craniofacial research. With the advent of the rapid development of research technologies, the past decade has seen vast accumulation of acquired data on human health and diseases. The biomedical data science is a new research discipline to best analyze the massive biomedical data sets to discover new knowledge about the function and mechanism of our health and disease, which is highly relevant to our future professionals in scientific research and clinical dentistry. Specific challenges in biomedical data science include the appropriate data curation system handling the datasets in a FAIR (Findable, Accessible, Interoperable, and Reusable) manner; the standardized scientific workflow systems to capture the provenance of data transformations; and the ethical challenge in dentistry for privacy, anonymity, security and informed consent using digital, electronic and mobile health records. The proposed educational modules will discuss these challenges in real life scenarios through an extended massive online course (xMOOC) format. Aim 1: The PD/PI will form the WORKING TEAM of committed faculty to [1] curate a bank of highly relevant case series with content advisors who are established in dental, oral and craniofacial research as well as biomedical data science; [2] design and develop case studies and problem sets; and [3] construct video clips with UCLA Instructional Media Production. Aim 2: The PD/PI and the WORKING TEAM will [1] establish the 5-module xMOOC training program; [2] develop forums and case discussion programs; and establish self- test problems. UCLA Center for Advancement of Teaching (CAT) is the campus resources assisting this process. Aim 3: The PD/PI and the WORKING TEAM will [1] initiate the pilot test with invited trainees; and [2] analyze the evaluation matrix and make necessary revisions. To succeed the development of the training module, the PD/PI and the WORKING TEAM will be supported by the educational program advisors and the content advisors solicited throughout from the rich research environment of UCLA. The Dean of UCLA School of Dentistry is committed to support this program development. Finally, the final version of the training module will be professionally evaluated by UCLA Center for the Advancement of Teaching, and disseminated through a non-profit MOOC provider and submitted to NIGMS.

项目概要/摘要 这个 R25 教育项目提议开发一套用于开始口腔生物学的培训模块 研究员和牙科专科住院医师。拟议的模块将介绍培训 负责任地开展专注于牙科、口腔和口腔领域生物医学数据科学的研究 颅面研究。随着研究技术的飞速发展，近十年来 我们已经积累了有关人类健康和疾病的大量数据。生物医学数据科学是一门新学科 研究学科能够最好地分析大量生物医学数据集，以发现有关生物医学的新知识 我们的健康和疾病的功能和机制，这与我们未来的专业人士高度相关 科学研究和临床牙科。 生物医学数据科学的具体挑战包括适当的数据管理系统处理 以公平（可查找、可访问、可互操作和可重用）方式存储数据集；标准化科学 工作流程系统捕获数据转换的来源；以及牙科领域的道德挑战 使用数字、电子和移动健康记录实现隐私、匿名、安全和知情同意。这 拟议的教育模块将通过扩展讨论现实生活场景中的这些挑战 大规模在线课程（xMOOC）格式。 目标 1：PD/PI 将组建一支由敬业的教师组成的工作团队，以 [1] 策划一批高度 相关案例系列以及在牙科、口腔和颅面研究领域建立的内容顾问 作为生物医学数据科学； [2] 设计和开发案例研究和问题集； [3]构建视频 与加州大学洛杉矶分校教学媒体制作的剪辑。目标 2：PD/PI 和工作团队将 [1] 建立 5 个模块的 xMOOC 培训计划； [2] 制定论坛和案例讨论计划；并建立自 测试问题。加州大学洛杉矶分校教学促进中心 (CAT) 是协助此目的的校园资源 过程。目标 3：PD/PI 和工作团队将 [1] 与受邀学员一起发起试点测试；和[2] 分析评估矩阵并进行必要的修改。 为了成功开发培训模块，PD/PI 和工作团队将 得到教育项目顾问和从富人那里征集的内容顾问的支持 加州大学洛杉矶分校的研究环境。加州大学洛杉矶分校牙科学院院长致力于支持该计划 发展。 最后，培训模块的最终版本将由加州大学洛杉矶分校中心进行专业评估 教学进步，通过非营利 MOOC 提供商传播并提交给 NIGMS。