Responsible Conduct of Research Training in Biomedical Data Science for Dental, Oral and Craniofacial Research

负责任地开展牙科、口腔和颅面研究生物医学数据科学研究培训

• 批准号: 10379291
• 负责人: ICHIRO NISHIMURA
• 金额: $ 9.78万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10379291
• 关键词: Address; Back; Case Series; Case Study; Certification; Clinical; Clip; Communities; Consult; Cues; Data; Data Provenance; Data Set; Dental; Dental Specialties; Dentistry; Development; Discipline; Disease; Educational process of instructing; Effectiveness; Environment; Ethics; Evaluation; FAIR principles; Faculty; Future; Goals; Health; Human; Individual; Informed Consent; Instruction; Interview; Knowledge; Learning; Learning Module; Licensing; Life; National Institute of General Medical Sciences; Oral; Privacy; Problem Sets; Process; Production; Program Development; Provider; Research; Research Training; Resources; Running; School Dentistry; Scientist; Security; Self Assessment; Specific qualifier value; Standardization; Surveys; System; Testing; Training; Training Activity; Training Programs; United States National Institutes of Health; Visual; Work; biomedical data science; craniofacial; data curation; design; digital; effectiveness evaluation; flexibility; graduate student; health record; improved; learning network; mHealth; massive open online courses; member; memory process; online course; oral biology; pilot test; programmed cell death protein 1; programs; responsible research conduct; self testing; skills; technology research and development; theories; work-study

PROJECT SUMMARY/ABSTRACT This R25 educational project proposes to develop a set of training modules for starting oral biology research fellows and dental specialty residents. The proposed modules will introduce the training in Responsible Conduct of Research focusing on biomedical data science in the field of dental, oral and craniofacial research. With the advent of the rapid development of research technologies, the past decade has seen vast accumulation of acquired data on human health and diseases. The biomedical data science is a new research discipline to best analyze the massive biomedical data sets to discover new knowledge about the function and mechanism of our health and disease, which is highly relevant to our future professionals in scientific research and clinical dentistry. Specific challenges in biomedical data science include the appropriate data curation system handling the datasets in a FAIR (Findable, Accessible, Interoperable, and Reusable) manner; the standardized scientific workflow systems to capture the provenance of data transformations; and the ethical challenge in dentistry for privacy, anonymity, security and informed consent using digital, electronic and mobile health records. The proposed educational modules will discuss these challenges in real life scenarios through an extended massive online course (xMOOC) format. Aim 1: The PD/PI will form the WORKING TEAM of committed faculty to [1] curate a bank of highly relevant case series with content advisors who are established in dental, oral and craniofacial research as well as biomedical data science; [2] design and develop case studies and problem sets; and [3] construct video clips with UCLA Instructional Media Production. Aim 2: The PD/PI and the WORKING TEAM will [1] establish the 5-module xMOOC training program; [2] develop forums and case discussion programs; and establish self- test problems. UCLA Center for Advancement of Teaching (CAT) is the campus resources assisting this process. Aim 3: The PD/PI and the WORKING TEAM will [1] initiate the pilot test with invited trainees; and [2] analyze the evaluation matrix and make necessary revisions. To succeed the development of the training module, the PD/PI and the WORKING TEAM will be supported by the educational program advisors and the content advisors solicited throughout from the rich research environment of UCLA. The Dean of UCLA School of Dentistry is committed to support this program development. Finally, the final version of the training module will be professionally evaluated by UCLA Center for the Advancement of Teaching, and disseminated through a non-profit MOOC provider and submitted to NIGMS.

项目总结/摘要 这个R25教育项目建议开发一套口腔生物学入门培训模块 研究员和牙科专科住院医师。拟议的培训单元将介绍 负责任的研究行为，重点是牙科，口腔和医学领域的生物医学数据科学 颅面研究随着研究技术的迅速发展，过去十年 积累了大量关于人类健康和疾病的数据。生物医学数据科学是一种新的 研究学科，以最好地分析大量的生物医学数据集，以发现新的知识， 我们的健康和疾病的功能和机制，这是高度相关的，我们未来的专业人士， 科学研究和临床牙科。 生物医学数据科学的具体挑战包括适当的数据管理系统处理 以公平的方式（可查找、可解释、可互操作和可重用）处理数据集; 工作流程系统，以捕捉数据转换的出处;以及牙科的道德挑战， 使用数字、电子和移动的健康记录来保护隐私、匿名、安全和知情同意。的 拟议的教育模块将讨论这些挑战，在真实的生活中的情况下，通过扩大 大规模在线课程（xMOOC）格式。 目标1：PD/PI将组成由忠诚的教师组成的工作团队，[1]策划一个高度专业的银行。 与牙科、口腔和颅面研究领域的内容顾问相关的病例系列 作为生物医学数据科学; [2]设计和开发案例研究和问题集;[3]构建视频 加州大学洛杉矶分校教学媒体制作。目标2：PD/PI和工作组将[1]建立 5个模块的xMOOC培训计划; [2]开发论坛和案例讨论计划;并建立自我- 测试问题。加州大学洛杉矶分校教学促进中心（CAT）是协助这一校园资源 过程目标3：方案司/主要研究者和工作组将[1]邀请受训人员开始试点测试;[2] 分析评估矩阵并进行必要的修改。 为成功开发培训模块，方案执行/方案执行主任和工作组将 由教育计划顾问和内容顾问提供支持， UCLA的研究环境。加州大学洛杉矶分校牙科学院院长致力于支持这一计划 发展 最后，培训模块的最终版本将由UCLA中心进行专业评估， 推进教学，并通过非营利MOOC提供商传播，并提交给NIGMS。