2022 Oxygen Radicals GRC/GRS

2022 氧自由基 GRC/GRS

• 批准号: 10387030
• 负责人: CHRISTIAN SCHONEICH
• 金额: $ 0.3万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-12-10 至 2023-04-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10387030
• 关键词: Academia; Address; Aging; Applied Research; Area; Atmosphere; Basic Science; Biochemistry; Biological; Biological Aging; Biological Process; Biology; California; Cardiometabolic Disease; Cells; Cellular Stress Response; Chemistry; Clinical Trials; Collaborations; Communication; Communities; Data Analytics; Development; Diagnosis; Discipline; Disease; Education; Ensure; Environment; Etiology; Evolution; Face; Female; Fertilization; Fostering; Funding; Future; Gene Expression Regulation; Generations; Goals; Government; Health; Hour; Immunity; Industry; Infection; Inflammatory; Knowledge; Lung diseases; Malignant Neoplasms; Malignant neoplasm of liver; Medical; Medicine; Methodology; Methods; Oral; Oxidation-Reduction; Oxidative Stress; Pathology; Pathway interactions; Physiological; Physiological Processes; Physiology; Play; Prognosis; Protein Biochemistry; Reaction; Reactive Oxygen Species; Research; Role; STEM field; Science; Scientific Advances and Accomplishments; Scientist; Seminal; Senior Scientist; Signal Pathway; Signal Transduction; Stress; System; Therapeutic; Time; Tissues; Training; Translations; Travel; Underrepresented Minority; United States; Woman; age related; bench to bedside; career development; clinical application; cost; design; diversity and inclusion; interest; large datasets; lectures; minority scientist; nervous system disorder; novel; novel therapeutics; obesity development; posters; programs; symposium; therapeutic development

Project Summary This application seeks support for the 2022 Gordon Research Conference (GRC) on Oxygen Radicals: Connecting the Chemistry of Oxygen Radicals to Medicine, taking place from January 30-February 4, 2022, and preceded by the Gordon Research Seminar (GRS), organized by trainees for trainees, on January 29-30, 2022. Both GRC and GRS will be held at the Ventura Beach Marriott in Ventura, California. We designed an exciting program, bringing together leading scientists and scientists in training, representing diverse fields of research on oxygen radicals, from basic chemistry to clinical applications and trials. The program focuses on advances in the chemistry, analysis, biochemistry, and biology of oxygen radicals, covering redox signaling in cancer, aging and age-related diseases, pulmonary diseases, neurological disorders, and cardiometabolic diseases. The program includes two keynote lectures entitled The KEAP1-NRF2 regulatory system and its role in health and disease and P62-NRF2 axis in the development of obesity-induced liver cancer, together with 31 additional invited lectures, presented by senior scientists and rising stars in the area of oxygen radicals. We have reserved 12 slots for oral presentations, selected from submitted abstracts. The organizers will ensure that women and underrepresented minority scientists will actively participate in the GRC, either through selection as invited speakers or discussion leaders, through selection for speaker slots from submitted abstracts, or as presenters of posters and presenters during the poster preview sessions. The poster preview sessions will be especially important to give poster presenters a brief time to introduce the main content of their posters to the audience, preparing all attendees for further vibrant exchange and discussions during the poster sessions. Among invited speakers and discussion leaders, 46% are female, and all attendees of the GRC will have the opportunity to address challenges women face in science and issues of diversity and inclusion during the Power Hour and Representation by Women session. The GRC will create an environment of inclusion and belonging, specifically integrating minorities and scientist in training into the community, for example through welcome tables. We will ensure that during discussion sections, trainees will be given priority to ask the first questions. Invited speakers will share cutting edge science and new discoveries the following sessions: Keynote session: Integrative cellular stress responses: redox control of gene regulation; Chemistry and analysis of redox stress; Redox biochemistry of proteins; Redox signaling in cancer: from mechanisms to therapy; Redox pathways in aging and age-related diseases; Redox mechanisms in neurological diseases; Novel methods to study redox signaling; Oxidative stress in infection, immunity and pulmonary diseases; Redox signaling in cardiometabolic diseases.

项目概要 本申请寻求 2022 年戈登氧自由基研究会议 (GRC) 的支持： 连接氧自由基的化学与医学，将于2022年1月30日至2月4日举行，以及 在此之前，由学员为学员举办的戈登研究研讨会 (GRS) 将于 2022 年 1 月 29 日至 30 日举行。 GRC 和 GRS 均将在加利福尼亚州文图拉的文图拉海滩万豪酒店举行。我们设计了一个令人兴奋的 计划，汇集了顶尖科学家和接受培训的科学家，代表了不同研究领域 氧自由基，从基础化学到临床应用和试验。该计划重点关注以下方面的进展 氧自由基的化学、分析、生物化学和生物学，涵盖癌症、衰老和衰老中的氧化还原信号传导 年龄相关疾病、肺部疾病、神经系统疾病和心脏代谢疾病。该计划 包括两个题为“KEAP1-NRF2 调控系统及其在健康和疾病中的作用”的主题演讲 和 P62-NRF2 轴在肥胖诱发的肝癌发展中的作用，以及另外 31 名受邀者 由氧自由基领域的资深科学家和后起之秀进行的​​讲座。我们预留了12个 从提交的摘要中选择的口头报告时段。主办方将确保女性和 代表性不足的少数族裔科学家将通过邀请选拔的方式积极参与 GRC 演讲者或讨论领导者，通过从提交的摘要中选择演讲者位置，或作为演示者 海报预览期间的海报和演示者。海报预览环节将特别 重要的是给海报展示者一个简短的时间向观众介绍他们海报的主要内容， 为所有与会者在海报会议期间进行进一步活跃的交流和讨论做好准备。受邀其中 演讲者和讨论领袖中，46%为女性，GRC的所有与会者将有机会 解决女性在科学领域面临的挑战以及“力量时刻”期间的多样性和包容性问题， 妇女代表会议。 GRC 将创造一个包容性和归属感的环境，特别是 将接受培训的少数群体和科学家融入社区，例如通过欢迎桌。我们将 确保在讨论部分，学员将优先提出第一个问题。特邀演讲嘉宾 将在以下会议上分享前沿科学和新发现： 主题演讲：整合细胞 应激反应：基因调控的氧化还原控制；氧化还原应力的化学和分析；氧化还原生物化学 蛋白质；癌症中的氧化还原信号：从机制到治疗；衰老和年龄相关的氧化还原途径 疾病；神经系统疾病中的氧化还原机制；研究氧化还原信号传导的新方法；氧化应激 感染、免疫和肺部疾病；心脏代谢疾病中的氧化还原信号传导。