CareBand: A Collaborative Pilot Study to Optimize a Life-Space Performance Metric for Monitoring and Early Detection of Alzheimer's Disease and Related Dementias in Rural and Indigenous Communities

CareBand：一项合作试点研究，旨在优化生活空间绩效指标，以监测和早期发现农村和土著社区的阿尔茨海默病和相关痴呆症

• 批准号: 10212745
• 负责人: Wayne Richard Warry
• 金额: $ 43.87万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10212745
• 关键词: Address; Aging; Algorithmic Analysis; Algorithms; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Behavior; Caregiver Burden; Caregivers; Caring; Cellular Phone; Cognitive; Communities; Complement; Data; Data Set; Dementia; Dementia caregivers; Development; Devices; Diagnosis; Early Diagnosis; Ensure; Environment; Ethics; Frequencies; Geography; Goals; Gold; Home; Impaired cognition; Incidence; Indigenous; Industry; Internet; Interview; Learning; Life; Life Style; Location; Measures; Medical; Memory; Minnesota; Monitor; Movement; Native-Born; Patient Self-Report; Performance; Persons; Physical environment; Pilot Projects; Population; Population Heterogeneity; Prevalence; Privatization; Reporting; Research; Research Personnel; Rural; Rural Community; Rural Population; Sampling; Services; Social Environment; Speed; System; Technology; Time; Translating; Uncertainty; Universities; age related; aging in place; base; clinical predictors; clinically relevant; community based participatory research; cost effective; data modeling; diaries; experience; falls; health care availability; health care service; health disparity populations; health equity; improved; indigenous community; industry partner; innovation; movement analysis; pre-clinical; rurality; sensor; technology development; validation studies; wearable device

Project Summary/Abstract Despite having higher rates of ADRD, increased caregiver stress and a lack of accessible healthcare services compared to urban counterparts, rural and Indigenous populations are grossly underrepresented in dementia research, especially in technology development. This R21 project, titled CareBand: A Collaborative Pilot Study to Optimize a Life-Space Performance Metric for Monitoring and Early Detection of ADRD in Rural and Indigenous Communities addresses urgent dementia disparities by developing aging-in-place technology to monitor dementia-related behaviours. This project brings together the University of Minnesota’s Memory Keepers - Medical Discover Team (MK-MDT) with an Industry partner, CareBand Inc., to digitize and expand existing metrics for the recording and analysis of movement through personal (in-home) and community environments, called life-space, using CareBand’s already available and proven, unobtrusive wearable wristband device. CareBand uses LoRa technology making it accessible to those without Internet or cellular services. This research will develop a new metric, a life-space performance (LSP) score, that will capture mobility through the exact calculation of distance based on amount, frequency and speed and as well as quality of movements (stability, falls, speed) across any clinically relevant period of time. Our long-term goal is to use LSP metrics to track cognitive decline from pre-clinical subjective cognitive complaints through all stages of ADRD among geographically and culturally diverse populations. Our overall hypothesis is that culture and geography are significant factors in determining one’s life-space and that the accurate measure of LSP in Indigenous and rural populations can be achieved by developing measures that account for their unique contexts. Using a community-based participatory research approach, we will partner with Indigenous and rural communities to pilot CareBand allowing us to collect data on rural and Indigenous life-space utilization to produce a LSP score that will benefit PWD and their caregivers. Our research has three specific aims. First, we will conduct depth interviews to generate qualitative data to inform the LSP data model by identifying and prioritizing the most critical life-space behaviors for directing care decisions. Second, the CareBand will be piloted for 12 weeks in rural and Indigenous with 20 People with Dementia caregivers, to capture location, movement and speed of movement inside and outside the home. Third, we will develop a set of algorithms by analyzing the qualitative and quantitative results captured in Aims 1 and 2 to create an LSP Score. This research will digitize life-space measures into a LSP score which includes indicators appropriate to rural and Indigenous populations and will lay the groundwork for a subsequent R01 application to validate the context specific LSP metrics against existing gold standards. The culturally appropriate LSP measure will contribute to health equity through improved early detection, diagnosis and care for rural and Indigenous populations.

项目总结/摘要 尽管ADRD的发病率较高，但护理人员的压力增加，缺乏可获得的医疗服务， 与城市相比，农村和土著人口在痴呆症中的代表性严重不足 研究，特别是技术开发。这个R21项目，名为CareBand：一个合作试点研究 优化农村ADRD监测和早期检测的生命空间性能指标， 原住民社区通过开发就地老化技术来解决紧迫的痴呆症差异， 监测痴呆症相关行为。这个项目汇集了明尼苏达大学的记忆 Keepers - Medical Discover Team（MK-MDT）与行业合作伙伴CareBand Inc.，扩大和发展 通过个人（家庭）和社区记录和分析运动的现有指标 环境，称为生活空间，使用CareBand的已经可用和证明，不显眼的可穿戴 腕带装置。CareBand使用LoRa技术，使那些没有互联网或手机的人也能使用它。 服务这项研究将开发一种新的衡量标准，即生命空间表现（LSP）评分， 通过基于数量、频率和速度精确计算距离， 任何临床相关时间段内的运动质量（稳定性、福尔斯、速度）。我们的长期目标是 使用LSP指标跟踪从临床前主观认知主诉到所有 在不同地理和文化的人群中，ADRD的各个阶段。我们的总体假设是文化 和地理是决定一个人生活空间的重要因素， 土著和农村人口可通过制定措施， contexts.使用以社区为基础的参与性研究方法，我们将与土著和农村 社区试点CareBand，使我们能够收集农村和土著生活空间利用的数据， 产生一个LSP评分，这将有利于残疾人及其照顾者。我们的研究有三个具体目标。一是 将进行深度访谈，以生成定性数据，通过识别和 优先考虑最关键的生活空间行为，以指导护理决策。其次，CareBand将 在农村和土著地区试点12周，有20名痴呆症患者照顾者，以捕捉位置， 移动和移动的速度在家里和外面。第三，我们将开发一套算法， 分析目标1和2中获得的定性和定量结果，以创建LSP评分。这 研究将把生活空间措施纳入LSP评分，其中包括适合农村和 土著居民，并将为随后的R 01应用程序奠定基础，以验证上下文 针对现有黄金标准的特定LSP指标。文化上适当的LSP措施将有助于 通过改善农村和土著人口的早期发现、诊断和护理，实现健康公平。