Addiction Telemedicine Consultation in Primary Care: Increasing Access to Pharmacotherapy and Specialty Treatment for Alcohol Problems

初级保健中的成瘾远程医疗咨询：增加酒精问题药物治疗和专业治疗的机会

• 批准号: 10212895
• 负责人: Stacy Ann Sterling
• 金额: $ 69.84万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-10 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10212895
• 关键词: Accident and Emergency department; Address; Adoption; Adult; Affect; Alcohol abuse; Alcohol consumption; Caring; Characteristics; Clinic; Clinical Pharmacists; Cluster randomized trial; Consult; Consultations; Data; Disulfiram; Drug Prescriptions; Effectiveness; Electronic Health Record; Electronic Mail; Elements; Feasibility Studies; Feedback; Formulation; Frequencies; Health Care Costs; Health Personnel; Health system; Healthcare Systems; Heavy Drinking; Injectable; Intervention; Interview; Literature; Logistics; Medical; Medicine; Modeling; Morbidity - disease rate; Naltrexone; Oral; Patient-Focused Outcomes; Patients; Pharmaceutical Preparations; Pharmacotherapy; Pilot Projects; Primary Care Physician; Primary Health Care; Provider; Public Health; Race; Research; Route; Services; Structure; Techniques; Telemedicine; Telephone; Time; Training; Training and Education; Visit; acamprosate; addiction; alcohol abuse therapy; alcohol misuse; alcohol screening and brief intervention; alcohol use disorder; arm; base; care providers; care systems; clinical care; continuing medical education; cost; design; drinking; ethnic disparity; evidence base; flexibility; follow-up; gender disparity; health service use; implementation barriers; implementation outcomes; improved; innovation; inpatient service; insight; medical specialties; mortality; motivational enhancement therapy; multi-component intervention; patient population; primary care setting; programs; public health relevance; routine care; screening, brief intervention, referral, and treatment; service utilization; socioeconomics; tool; treatment arm; treatment as usual; urgent care; usual care arm

ABSTRACT Alcohol use disorders (AUDs) are a major public health problem and pose significant challenges to clinicians, patients, and health systems. AUDs are associated with serious medical conditions, can complicate medical treatment and increase avoidable health service utilization and costs. Yet most patients who would benefit from evidence-based AUD treatment, including pharmacotherapy, do not receive these services. Although medications such as naltrexone, acamprosate and disulfiram can be effective for moderate to severe alcohol problems, primary care providers (PCPs) are often reluctant to prescribe, and AUD medications remain underused. Innovative care models are needed to give PCPs the tools they need to address AUDs in primary care settings, but few studies have examined interventions to improve AUD medication delivery and specialty care initiation. To address this substantial gap in the evidence base, this pragmatic, cluster-randomized trial in adult primary care clinics (n=20) in a large, ethnically and socioeconomically diverse healthcare system, will examine the effectiveness of an innovative, multi-faceted intervention: the Addiction Telemedicine Consultant service, or “ATC.” The ATC provides a flexible, efficient, centralized approach to bringing Addiction Medicine expertise directly into primary care. PCPs can access the ATC via three routes: real-time video or telephone connection during primary care visits, asynchronous email, and telephone consultation. The ATC, a clinical pharmacist, may assess the patient, discuss appropriate AUD medications with the PCP and patient, and if appropriate, guide the PCP through prescribing logistics, or initiate the prescription themselves. The motivational interviewing-trained ATC may also encourage the patient to initiate specialty addiction treatment and facilitate connection to a local program. The ATC intervention will also offer initial continuing medical education training on AUDs and AUD medication prescribing, and ongoing technical assistance, to all PCPs in the ATC arm. We will compare the ATC arm to Usual Care, which includes routine alcohol screening, brief intervention and referral to treatment (SBIRT) in primary care. We conducted a pilot feasibility study of the ATC model, and the proposed trial builds on our pilot findings, the extant literature, and incorporates stakeholder feedback in its design. We will use electronic health record data captured during the course of regular clinical care to examine treatment arm effects on implementation outcomes (AUD medication prescription rates and addiction treatment referral rates) and patient outcomes (AUD medication fill rates, addiction treatment initiation, alcohol use (drinking days/week, # drinks/week, # of “heavy” drinking days (4+/5+/day) in past 90 days), and health services utilization and costs, over two years. If the intervention is effective, this study has the capacity to spur the use of safe, effective pharmacotherapy for AUDs as a standard practice in primary care settings and profoundly affect how we treat and study the full spectrum of alcohol use problems.

摘要 酒精使用障碍（AUDs）是一个主要的公共卫生问题，并构成重大挑战， 临床医生、患者和卫生系统。AUD与严重的医疗状况有关，可能使 医疗和增加可避免的卫生服务利用和成本。然而，大多数患者 受益于循证AUD治疗（包括药物治疗）的患者不接受这些服务。 尽管纳洛酮、阿坎酸和双硫仑等药物对中度至重度的糖尿病患者有效， 酒精问题，初级保健提供者（PCP）往往不愿意开药，AUD药物仍然存在 未充分利用需要创新的护理模式，为PCP提供解决小学AUD所需的工具 护理环境，但很少有研究检查干预措施，以改善AUD药物输送和专业 护理启动。为了解决证据基础中的这一实质性差距，这项务实的，随机分组试验， 在一个大型的、种族和社会经济多样化的医疗保健系统中，成人初级保健诊所（n=20）将 检查一个创新的，多方面的干预的有效性：成瘾远程医疗顾问 服务，或“ATC”。ATC提供了一种灵活、高效、集中的方法， 专业知识直接进入初级保健。PCP可以通过三种途径访问ATC：实时视频或电话 初级保健访问期间的连接，异步电子邮件和电话咨询。ATC，临床 药剂师可以评估患者，与PCP和患者讨论适当的AUD药物，如果 适当时，通过处方物流指导PCP，或自己开处方。的 经过动机访谈训练的ATC也可以鼓励患者开始专业成瘾治疗 并便于连接到本地程序。ATC干预还将提供初步的持续医疗服务， 向所有PCP提供关于AUD和AUD药物处方的教育培训，以及持续的技术援助， ATC臂。我们将比较ATC臂的日常护理，其中包括常规酒精筛查，简要 干预和转诊治疗（SBIRT）。我们进行了一项可行性试验研究， ATC模型，拟议的试验建立在我们的试点结果，现存的文献，并结合 利益攸关方在其设计中的反馈意见。我们将使用在以下过程中捕获的电子健康记录数据 定期临床护理，以检查治疗组对实施结局的影响（AUD药物 处方率和成瘾治疗转诊率）和患者结果（AUD药物填充率， 成瘾治疗开始、酒精使用（饮酒天数/周、饮酒次数/周、“重度”饮酒天数 （过去90天4+/5+/天）以及两年的保健服务利用率和费用。如果干预是 有效，这项研究有能力刺激使用安全，有效的药物治疗AUDs作为标准 在初级保健环境中的实践，并深刻影响我们如何治疗和研究酒精使用的全方位 问题