The MobileToolbox for Monitoring Cognitive Function - Technical Core

用于监测认知功能的 MobileToolbox - 技术核心

• 批准号: 10212848
• 负责人: Maria Varela Diaz
• 金额: $ 64.28万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10212848
• 关键词: Address; Adopted; Adoption; Alzheimer' s Disease; Android; Biomedical Research; Cellular Phone; Clinical; Code; Cognition; Cognitive; Collaborations; Collection; Communities; Computer software; Consult; Custom; Data; Data Analyses; Data Collection; Development; Documentation; Ensure; Face; Goals; Health; Human; Individual; Infrastructure; Libraries; Longevity; Measures; Mission; Modeling; Monitor; Participant; Patient Recruitments; Physiological; Privacy; Protocols documentation; Publishing; Research; Research Personnel; Science; Scientist; Secure; Self Administration; Services; Statistical Data Interpretation; Synapses; System; Technology; Testing; Translating; United States National Institutes of Health; Universities; Validation; Work; Writing; application programming interface; base; cloud based; cognitive function; cognitive testing; experience; handheld mobile device; health data; mHealth; mobile application; novel; open source; programs; research study; smartphone based assessment; software development; support tools; tool; web services

Technical Core Summary The Technical Core will provide general infrastructure and tools to address technical challenges in adopting mobile approaches to research including: participant recruitment, retention, and support; technological validation of new assessments; and securing data appropriately. We will provide the NIH an open and extensible technology platform for conducting mobile health research that has already been successfully deployed in over 20 different mobile health research studies by Sage Bionetworks and its partners. This platform includes Bridge Server, an open-source set of cloud-based web services and tools that support the secure deployment of mobile approaches and Synapse, a system for managing the dissemination of biomedical research data to researchers worldwide. In our first year, we will adapt a set of commonly used cognitive assessments for mobile implementations, and integrate these modules. Technology experts and scientists will work closely together to develop and validate the measures. This will serve as a model for provision of more general support for novel measure development by external developers in later years of the program, further expanding MobileToolbox. We will achieve our overall goal to support the development and dissemination of a broad set of mobile measures of human cognition via these Aims: Aim 1: We will extend and support the Center’s technology platform to serve the needs of the other center cores, external technology developers, and researchers. We will support the development of novel mobile measures of cognition through open Application Program Interfaces (APIs), Software Development Kits (SDKs), and standards that allow any researcher to publish new assessments of cognition through our platform. We will develop tools for researchers to easily create, configure, and deploy mobile measures of cognition into their own research studies, all without requiring writing new software code for each study. We will support the collection and dissemination of mobile health data and study results in a way that prioritizes the broad and rapid adoption of mobile cognitive assessments by the research community. Aim 2: We will select and develop a representative set of mobile measures covering a wide range of cognitive domains. Specific measures will be selected through interactions with the other cores, and validated though the data and statistical analysis core. We will support the Dissemination Core by releasing normative data, technical documentation, and best practices, and by offering customized consulting services to ensure the assessments achieve widespread adoption and impact.

技术核心摘要 技术核心将提供通用基础设施和工具，以解决采用 移动的研究方法包括：参与者招募、保留和支持;技术 验证新的评估;适当保护数据。我们将为NIH提供一个开放的， 一个可扩展的技术平台，用于进行移动的健康研究，该平台已经成功地 Sage Bionetworks及其合作伙伴在20多项不同的移动的健康研究中部署了该技术。这 该平台包括Bridge Server，这是一套开源的基于云的Web服务和工具，支持 安全部署移动的方法和Synapse，一个管理 向全世界的研究人员提供生物医学研究数据。在第一年，我们将采用一套常用的 认知评估的移动的实施，并整合这些模块。技术专家和 科学家们将密切合作，制定和验证这些措施。这将作为一个模型， 为外部开发人员在以后几年的新措施开发提供更普遍的支持， 计划，进一步扩展MobileToolbox。我们将实现支持发展的总体目标， 通过以下目标传播一套广泛的人类认知移动的测量方法： 目标1：我们将扩展和支持中心的技术平台，以满足对方的需求 中心核心、外部技术开发人员和研究人员。我们将支持小说的发展 移动的认知测量通过开放的应用程序接口（API）、软件开发工具包 （SDK），以及允许任何研究人员通过我们的 平台我们将为研究人员开发工具，以轻松创建，配置和部署移动的措施， 将认知融入到自己的研究中，而无需为每个研究编写新的软件代码。我们将 支持收集和传播移动的卫生数据和研究结果， 研究界广泛而迅速地采用移动的认知评估。 目标2：我们会选择及制订一套具代表性的移动的措施，涵盖多个范畴， 认知领域将通过与其他核心的互动来选择具体措施， 通过数据和统计分析核心验证。我们将通过发布 规范数据、技术文档和最佳实践，并提供定制咨询服务， 确保评估得到广泛采用并产生广泛影响。