Integrated Health Sciences Facility Core

项目摘要-综合健康科学设施核心 综合健康科学设施核心(IHSFC)将继续是环境健康和 与疾病相关的翻译研究。加州大学戴维斯分校在动物和 体外机械环境健康研究在许多实验室中进行，包括在高度... 排名第一的兽医学院，农业与环境科学学院 生物科学。为更好地为扩展我们的环境健康研究工作做准备 在创新干预和人类研究方面，我们的领导和研究能力这一核心 扩大了。总体而言，关键资源的访问将由加州大学戴维斯分校环境健康中心提供 科学核心中心(EHSCC)IHSFC用于体外研究、动物模型、生物统计学、新型传感器和 生物标志物技术，以及用于人类研究和灾害应对的转化性研究资源 研究。具体地说，我们的目标是1)推动EHSCC研究项目沿着翻译研究方向发展 管道使用体外测试，体内实验幼鱼，啮齿动物和非人灵长类动物模型，以及 流行病学和人体研究，2)为新的和 成熟的环境健康研究人员，3)开发和实施新的工具和技术 环境健康科学研究，以及4)建立加州大学戴维斯分校环境健康科学快速 能够迅速动员起来立即与受环境影响的人群接触的响应团队 灾难，例如野火。这些资源对于中心实现其深化的总体目标至关重要 我们对环境暴露如何影响人类健康的理解，因此，IHSFC将发挥至关重要的作用 在加州大学戴维斯分校将EHS相关研究带入减少疾病和干预的应用和干预中的作用 残疾和促进环境公共健康在我们的目标地区加利福尼亚州北部和 中央山谷，以及整个世界。

PROJECT SUMMARY – Integrative Health Sciences Facility Core The Integrative Health Sciences Facility Core (IHSFC) will continue to be the hub of environmental health and disease-related translational research. UC Davis has long-standing, recognized expertise in animal and in vitro mechanistic environmental health research housed in numerous laboratories including in the highly- ranked School of Veterinary Medicine, College of Agriculture and Environmental Sciences and the College of Biological Sciences. To better prepare for extension of our environmental health research efforts to translate into innovative intervention and human studies, our leadership and research capacity of this core has expanded. Overall, access to critical resources will be provided by the UC Davis Environmental Health Sciences Core Center (EHSCC) IHSFC for in vitro studies, animal models, biostatistics, novel sensor and biomarker technologies, and translational research resources for human studies and disaster response research. Specifically, our aims are to 1) promote EHSCC research projects along the translational research pipeline using in vitro assays, in vivo experimental larval fish, rodent and non-human primate models, and epidemiology and human studies, 2) provide biostatistical consultation and study design expertise to new and established environmental health researchers, 3) develop and implement new tools and technologies for environmental health sciences research, and 4) establish a UC Davis Environmental Health Sciences Rapid Response team that can mobilize quickly to immediately engage populations affected by environmental disasters, e.g. wildfires. These resources are critical for the center to achieve its overarching goal to deepen our understanding of how environmental exposures affect human health and, thus, the IHSFC will play a vital role in bringing EHS-related research at UC Davis to applications and interventions that reduce disease and disability, and promoting environmental public health both in our targeted region of California’s Northern and Central Valley, and throughout the world.