Integrated Health Sciences Facility Core

项目概要-综合健康科学设施核心 综合健康科学设施核心（IHSFC）将继续成为环境健康和 疾病相关的转化研究。加州大学戴维斯分校拥有长期的，公认的专业知识，在动物和 体外机械环境健康研究设在许多实验室，包括在高度- 排名兽医学院，农业和环境科学学院和 生物科学。为了更好地准备扩大我们的环境健康研究工作， 创新干预和人类研究，我们的领导和研究能力，这一核心已经 扩大总体而言，加州大学戴维斯分校环境健康中心将提供关键资源 科学核心中心（EHSCC）IHSFC，用于体外研究、动物模型、生物统计学、新型传感器和 生物标志物技术，以及人类研究和灾害应对的转化研究资源 research.具体来说，我们的目标是：1）沿着翻译研究，促进EHSCC研究项目 使用体外分析、体内实验幼鱼、啮齿动物和非人灵长类动物模型的管道，以及 流行病学和人类研究，2）提供生物统计咨询和研究设计专业知识， 建立环境卫生研究人员，3）开发和实施新的工具和技术， 环境健康科学研究，4）建立加州大学戴维斯分校环境健康科学快速 能够迅速动员起来，立即与受环境影响的人群接触的应急小组 灾害，例如野火。这些资源对于中心实现其总体目标至关重要， 我们对环境暴露如何影响人类健康的理解，因此，IHSFC将发挥至关重要的作用， 在将加州大学戴维斯分校的EHS相关研究应用于减少疾病和 残疾，并促进环境公共卫生都在我们的目标地区加州的北方和 中央谷，乃至全世界。

PROJECT SUMMARY – Integrative Health Sciences Facility Core The Integrative Health Sciences Facility Core (IHSFC) will continue to be the hub of environmental health and disease-related translational research. UC Davis has long-standing, recognized expertise in animal and in vitro mechanistic environmental health research housed in numerous laboratories including in the highly- ranked School of Veterinary Medicine, College of Agriculture and Environmental Sciences and the College of Biological Sciences. To better prepare for extension of our environmental health research efforts to translate into innovative intervention and human studies, our leadership and research capacity of this core has expanded. Overall, access to critical resources will be provided by the UC Davis Environmental Health Sciences Core Center (EHSCC) IHSFC for in vitro studies, animal models, biostatistics, novel sensor and biomarker technologies, and translational research resources for human studies and disaster response research. Specifically, our aims are to 1) promote EHSCC research projects along the translational research pipeline using in vitro assays, in vivo experimental larval fish, rodent and non-human primate models, and epidemiology and human studies, 2) provide biostatistical consultation and study design expertise to new and established environmental health researchers, 3) develop and implement new tools and technologies for environmental health sciences research, and 4) establish a UC Davis Environmental Health Sciences Rapid Response team that can mobilize quickly to immediately engage populations affected by environmental disasters, e.g. wildfires. These resources are critical for the center to achieve its overarching goal to deepen our understanding of how environmental exposures affect human health and, thus, the IHSFC will play a vital role in bringing EHS-related research at UC Davis to applications and interventions that reduce disease and disability, and promoting environmental public health both in our targeted region of California’s Northern and Central Valley, and throughout the world.