San Diego StrokeNet Regional Coordinating Center

圣地亚哥 StrokeNet 区域协调中心

• 批准号: 10217266
• 负责人: BRETT C MEYER
• 金额: $ 25.2万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10217266
• 关键词: Acute; Address; Advisory Committees; Agreement; Area; Brain; Caliber; Caring; Clinical Research; Clinical Trials; Contracts; Country; Coupled; Development; Devices; Diffuse; Discipline; Educational process of instructing; Enrollment; Ensure; Fellowship; Funding; Future; Generations; Grant; Health; Individual; Industry; Infrastructure; Institutional Review Boards; Intervention; Knowledge; Leadership; Manuscripts; Mentors; Mission; National Institute of Neurological Disorders and Stroke; Nerve Regeneration; Outcome; Participant; Patients; Pediatrics; Performance; Population; Procedures; Process; Productivity; Public Health; Publications; Recording of previous events; Recovery; Rehabilitation therapy; Research; Research Activity; Research Personnel; Research Training; Resources; Science; Site; Specialist; Stroke; Stroke prevention; StrokeNet trials; Techniques; Time; Training; Training Programs; United States; United States National Institutes of Health; Vocational Guidance; Work; acute stroke; base; care delivery; career; career development; clinical trial enrollment; data management; design; experience; faculty research; imaging biomarker; improved; investigator training; lectures; multi-site trial; multidisciplinary; nervous system disorder; programs; research and development; stroke clinical trials; stroke patient; stroke trials; success; time interval; tool; working group

The San Diego RCC is dedicated to the StrokeNet aims of delivering “Efficiency”, “Enrollments”, and “Training” by creating an optimized network, increasing trial enrollments, and enhancing career development. The results of this application will impact the stroke research field by enabling the discovery of acute, preventative, rehabilitation, recovery, neural regeneration, and imaging and biomarker techniques for stroke. UCSD is poised to continue to contribute to StrokeNet and support the NINDS' mission to seek knowledge about the brain and nervous system to reduce the burden of neurological disease. Program: UCSD has participated in SPOTRIAS, StrokeNet, NIH, and industry trials in various areas of stroke with leadership and participation in over 50 stroke trials. The network has developed out of a local network, expanded over time and now includes 30 centers spanning three states. All sites have active Master Trial Agreements and Reliance Agreements in place. The UCSD Stroke Center has again engaged the support of the Dean, Chair, IRB, Contracting Office, CTRI, ED, EMS, and network investigators for this proposal. Research: The next cycle will focus on conducting trials and enrolling participants in the 30 RCC centers. The RCC-12 has a strong pool of potential network investigators who have set up their infrastructure and are awaiting to participate in a network trial. We also have the proven capacity to perform trials in pediatrics and rehab. UCSD has submitted trial ideas and as has others in development for proposal into the network. Leadership: UCSD has designated a PI (Meyer) and substitute PI (Hemmen), each with qualifications to serve effectively. UCSD serves on the Acute Stroke Working Group and the Neuro-Interventional Advisory Committee. In the multidisciplinary clinical trials' team, experts from various disciplines are available to collaborate on trials in diverse arenas of stroke management. Trials particularly suited to areas of expertise of research faculty are assigned by the RCC-PI based on area of expertise. Career Enhancement: The Stroke Center has had full commitment to career guidance for trainees since 1987. The StrokeNet Career Enhancement Director (Hemmen) also serves as the fellow mentor for independent research activities. The training program focuses on research for the entire spectrum of stroke care. Didactic lectures and seminars are offered in diffuse topics. Administration: UCSD has had great success in producing high quality research, publications, and NIH trial enrollments due training on and following standard operating procedures (SOPs). The UCSD Stroke Center prioritizes StrokeNet and NIH funded trials as possible. Allocations grids mitigate against bias by guiding trial offerings fairly. Over the past 30 years, the UCSD Stroke Center has successfully performed trials in the full spectrum of stroke care, and is an ideal choice to continue leading a StrokeNet RCC.

圣地亚哥RCC致力于StrokeNet的目标，即提供“效率”、“注册”和 通过创建优化的网络、增加试行入学人数和促进职业发展来进行“培训”。 这一应用的结果将通过能够发现急性、 中风的预防、康复、康复、神经再生、成像和生物标记技术。 UCSD准备继续为StrokeNet做出贡献，并支持NINDS寻求知识的使命 关于大脑和神经系统，以减轻神经系统疾病的负担。 计划：UCSD参与了SPOTRIAS、StrokeNet、NIH和行业试验的各个领域 在50多个中风试验中发挥领导和参与作用。这个网络已经从一个本地的 网络，随着时间的推移而扩大，现在包括横跨三个州的30个中心。所有站点都有活动的主站点 试验协议和信赖性协议到位。加州大学圣地亚哥分校卒中中心再次提供支持 本提案的院长、主席、IRB、合同办公室、CTRI、ED、EMS和网络调查人员。 研究：下一个周期将集中在30个RCC中心进行试验和招募参与者。 RCC-12拥有一支强大的潜在网络调查员队伍，他们已经建立了基础设施，并 等待参加网络试验。我们也有被证明有能力进行儿科和 戒毒所。加州大学圣迭戈分校已经提交了试验想法，其他想法也在开发中，以便向该网络提出建议。 领导：加州大学圣迭戈分校指定了一名派(迈耶)和一名替补派(希曼)，每个人都有资格 高效服务。UCSD是急性卒中工作组和神经介入咨询机构的成员 委员会审议阶段。在多学科临床试验团队中，来自不同学科的专家可以 在中风治疗的不同领域合作进行试验。特别适合于以下领域的试验 研究人员由RCC-PI根据专业领域进行分配。 职业提升：卒中中心一直致力于为实习生提供职业指导 1987年。StrokeNet职业提升总监(赫曼)也是 自主研究活动。训练计划的重点是研究整个中风的范围。 关心。授课讲座和研讨会以分散的主题提供。 管理：加州大学圣迭戈分校在生产高质量的研究、出版物和NIH方面取得了巨大成功 试用登记应接受标准操作程序(SOP)方面的培训。加州大学洛杉矶分校的中风 中心尽可能优先考虑StrokeNet和NIH资助的试验。分配网格通过以下方式减轻偏差 公平引导试行。在过去的30年里，加州大学圣地亚哥分校中风中心成功地进行了试验 在全方位的中风护理中，是继续领导StrokeNet RCC的理想选择。