San Diego StrokeNet Regional Coordinating Center

项目摘要 圣地亚哥RCC致力于StrokeNet提供“效率”、“注册”和“培训”的目标。 通过创建优化的网络，增加试用入学人数，促进职业发展。结果是 这一应用的应用将通过使发现急性、预防性、 中风的康复、康复、神经再生、成像和生物标记技术。加州大学圣地亚哥分校已做好准备 继续为StrokeNet做出贡献，并支持NINDS的使命，即寻求关于大脑和 减轻神经系统疾病的负担。 计划：UCSD参与了SPOTRIAS、StrokeNet、NIH和中风各个领域的行业试验 在50多项中风试验中发挥领导和参与作用。该网络已从本地网络发展而来， 随着时间的推移而扩大，现在包括横跨三个州的30个中心。所有站点都有活动的主要试用版 协议和信赖性协议到位。加州大学圣地亚哥分校卒中中心再次邀请 本建议书的院长、主席、IRB、合同办公室、CTRI、ED、EMS和网络调查人员。 研究：下一个周期将集中在30个RCC中心进行试验和招募参与者。这个 RCC-12拥有一支强大的潜在网络调查人员队伍，他们已经建立了基础设施，正在等待 参加网络试运行。我们也有能力在儿科和康复方面进行试验。加州大学圣迭戈分校 已经提交了试验想法，还有其他正在开发中的想法，正在向网络提交建议。 领导：加州大学圣迭戈分校指定了一名派(迈耶)和一名替补派(赫曼)，每个人都有任职资格 有效地。UCSD是急性卒中工作组和神经介入咨询委员会的成员。 在多学科临床试验团队中，来自不同学科的专家可以协作进行试验 在中风治疗的不同领域。特别适合研究人员专业领域的试验是 由RCC-PI根据其专业领域进行分配。 职业提升：卒中中心自1987年以来一直致力于为实习生提供职业指导。 StrokeNet职业提升总监(赫曼)也是独立的伙伴导师 研究活动。该培训计划侧重于对中风护理的整个范围进行研究。说教 讲座和研讨会以分散的主题提供。 管理：加州大学圣迭戈分校在生产高质量的研究、出版物和NIH试验方面取得了巨大成功 注册应接受有关标准操作程序(SOP)的培训，并遵循该程序。加州大学洛杉矶分校的卒中中心 尽可能优先考虑StrokeNet和NIH资助的试验。分配网格通过指导试验来缓解偏见 公平地奉献。在过去的30年里，加州大学洛杉矶分校卒中中心成功地进行了全面的试验 是中风护理的最佳选择，是继续领导StrokeNet RCC的理想选择。

Project Summary The San Diego RCC is dedicated to the StrokeNet aims of delivering “Efficiency”, “Enrollments”, and “Training” by creating an optimized network, increasing trial enrollments, and enhancing career development. The results of this application will impact the stroke research field by enabling the discovery of acute, preventative, rehabilitation, recovery, neural regeneration, and imaging and biomarker techniques for stroke. UCSD is poised to continue to contribute to StrokeNet and support the NINDS’ mission to seek knowledge about the brain and nervous system to reduce the burden of neurological disease. Program: UCSD has participated in SPOTRIAS, StrokeNet, NIH, and industry trials in various areas of stroke with leadership and participation in over 50 stroke trials. The network has developed out of a local network, expanded over time and now includes 30 centers spanning three states. All sites have active Master Trial Agreements and Reliance Agreements in place. The UCSD Stroke Center has again engaged the support of the Dean, Chair, IRB, Contracting Office, CTRI, ED, EMS, and network investigators for this proposal. Research: The next cycle will focus on conducting trials and enrolling participants in the 30 RCC centers. The RCC-12 has a strong pool of potential network investigators who have set up their infrastructure and are awaiting to participate in a network trial. We also have the proven capacity to perform trials in pediatrics and rehab. UCSD has submitted trial ideas and as has others in development for proposal into the network. Leadership: UCSD has designated a PI (Meyer) and substitute PI (Hemmen), each with qualifications to serve effectively. UCSD serves on the Acute Stroke Working Group and the Neuro-Interventional Advisory Committee. In the multidisciplinary clinical trials’ team, experts from various disciplines are available to collaborate on trials in diverse arenas of stroke management. Trials particularly suited to areas of expertise of research faculty are assigned by the RCC-PI based on area of expertise. Career Enhancement: The Stroke Center has had full commitment to career guidance for trainees since 1987. The StrokeNet Career Enhancement Director (Hemmen) also serves as the fellow mentor for independent research activities. The training program focuses on research for the entire spectrum of stroke care. Didactic lectures and seminars are offered in diffuse topics. Administration: UCSD has had great success in producing high quality research, publications, and NIH trial enrollments due training on and following standard operating procedures (SOPs). The UCSD Stroke Center prioritizes StrokeNet and NIH funded trials as possible. Allocations grids mitigate against bias by guiding trial offerings fairly. Over the past 30 years, the UCSD Stroke Center has successfully performed trials in the full spectrum of stroke care, and is an ideal choice to continue leading a StrokeNet RCC.