San Diego StrokeNet Regional Coordinating Center

项目摘要 圣地亚哥RCC致力于提供“效率”，“注册”和“培训”的StrokeNet目标 通过创建优化的网络，增加试验入组，并加强职业发展。结果 该应用的研究将通过发现急性，预防性， 康复，恢复，神经再生，以及中风的成像和生物标志物技术。加州大学圣地亚哥分校 继续为StrokeNet做出贡献，并支持NINDS的使命，寻求有关大脑的知识， 减轻神经系统疾病的负担。 项目：UCSD参与了SPOTRIAS、StrokeNet、NIH和中风各个领域的行业试验 领导并参与了50多项中风试验。该网络是从本地网络发展而来的， 随着时间的推移不断扩大，现在包括跨越三个州的30个中心。所有研究中心都有活跃的主试验 协议和信赖协议到位。加州大学圣地亚哥分校中风中心再次获得了 院长、主席、IRB、合同办公室、CTRI、艾德、EMS和本提案的网络研究者。 研究：下一个周期将侧重于在30个RCC中心进行试验和招募参与者。的 RCC-12有一个强大的潜在网络调查人员库，他们已经建立了基础设施，正在等待 参加网络试验。我们也有能力在儿科和康复中心进行试验。UCSD 已经提交了试验性的想法，其他正在开发的想法也已提交给网络。 领导：UCSD已经指定了一个PI（迈耶）和替代PI（Hemmen），每个人都有资格任职 有效地UCSD是急性中风工作组和神经介入咨询委员会的成员。 在多学科临床试验团队中，来自各个学科的专家可以合作进行试验 在中风管理的不同领域。特别适合研究人员专业领域的试验是 由RCC-PI根据专业领域分配。 职业发展：自1987年以来，中风中心一直致力于为学员提供职业指导。 StrokeNet职业发展总监（Hemmen）还担任独立的导师 研究活动。培训计划的重点是研究中风护理的整个频谱。说教 讲座和研讨会以广泛的主题提供。 管理：UCSD在产生高质量的研究，出版物和NIH试验方面取得了巨大的成功 参加关于和遵守标准作业程序的培训。UCSD中风中心 尽可能优先考虑StrokeNet和NIH资助的试验。分配网格通过指导试验减轻偏倚 公平的报价。在过去的30年里，UCSD中风中心成功地进行了全面的试验， 中风护理的频谱，是一个理想的选择，继续领导中风网RCC。

Project Summary The San Diego RCC is dedicated to the StrokeNet aims of delivering “Efficiency”, “Enrollments”, and “Training” by creating an optimized network, increasing trial enrollments, and enhancing career development. The results of this application will impact the stroke research field by enabling the discovery of acute, preventative, rehabilitation, recovery, neural regeneration, and imaging and biomarker techniques for stroke. UCSD is poised to continue to contribute to StrokeNet and support the NINDS’ mission to seek knowledge about the brain and nervous system to reduce the burden of neurological disease. Program: UCSD has participated in SPOTRIAS, StrokeNet, NIH, and industry trials in various areas of stroke with leadership and participation in over 50 stroke trials. The network has developed out of a local network, expanded over time and now includes 30 centers spanning three states. All sites have active Master Trial Agreements and Reliance Agreements in place. The UCSD Stroke Center has again engaged the support of the Dean, Chair, IRB, Contracting Office, CTRI, ED, EMS, and network investigators for this proposal. Research: The next cycle will focus on conducting trials and enrolling participants in the 30 RCC centers. The RCC-12 has a strong pool of potential network investigators who have set up their infrastructure and are awaiting to participate in a network trial. We also have the proven capacity to perform trials in pediatrics and rehab. UCSD has submitted trial ideas and as has others in development for proposal into the network. Leadership: UCSD has designated a PI (Meyer) and substitute PI (Hemmen), each with qualifications to serve effectively. UCSD serves on the Acute Stroke Working Group and the Neuro-Interventional Advisory Committee. In the multidisciplinary clinical trials’ team, experts from various disciplines are available to collaborate on trials in diverse arenas of stroke management. Trials particularly suited to areas of expertise of research faculty are assigned by the RCC-PI based on area of expertise. Career Enhancement: The Stroke Center has had full commitment to career guidance for trainees since 1987. The StrokeNet Career Enhancement Director (Hemmen) also serves as the fellow mentor for independent research activities. The training program focuses on research for the entire spectrum of stroke care. Didactic lectures and seminars are offered in diffuse topics. Administration: UCSD has had great success in producing high quality research, publications, and NIH trial enrollments due training on and following standard operating procedures (SOPs). The UCSD Stroke Center prioritizes StrokeNet and NIH funded trials as possible. Allocations grids mitigate against bias by guiding trial offerings fairly. Over the past 30 years, the UCSD Stroke Center has successfully performed trials in the full spectrum of stroke care, and is an ideal choice to continue leading a StrokeNet RCC.