The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern University

摘要 我们提议在西北大学设立美国老年人独立中心（OAIC）。其使命是： 开展创新研究，加强对病情复杂的老年人的初级保健 多种慢性病 (MCC)，以实现最佳的健康、功能、独立性和生活质量。 西北大学 OAIC 将促进以下方面的研究： i) 确定可修改的临床、医疗保健系统和 慢性病结果、身心健康和生活质量的社会环境决定因素 对于患有 MCC 的老年人，尤其是体弱者； ii) 发展新颖、实用且可扩展的初级保健 符合患者优先事项、改善健康结果并保持独立性的管理策略 对于这个脆弱的、高危的老年人群。西北 OAIC 的具体目标是： 目标 1 正式制定一个全面的、多学科的老龄化研究计划，致力于改善 患有 MCC 的老年人的医疗保健、功能独立性和生活质量。 目标 2 扩大西北大学的培训和指导活动，培养老年病学和老龄化领域的未来领导者 研究将改变医疗保健以满足患有 MCC 的老年人的需求。 目标 3 促进与优先事项相一致的初级保健模式创新设计的应用研究 通过针对老龄化的研究资源和医疗保健系统的专业知识，了解患有 MCC 的老年人 和技术设计（“设计核心”），患者报告的结果测量（“测量核心”） 以及定量和定性数据分析（“分析核心”）。 凭借强大的制度支持和完善的基础设施，我们将组织国际认可的老龄化活动 西北大学的研究人员，并建立了一个正式的老龄化合作中心。初级 对老龄化和 MCC 相关研究感兴趣的教师将作为指导科学家参与；我们的 OAIC 将提供帮助 他们作为独立调查员建立了成功的职业轨迹。三个基本资源核心 （设计、测量、分析）将产生新的方法来解决初级 MCC 问题 通过试点和开发项目来护理和促进卫生系统干预措施的设计和测试，以及 通过使用大量正在进行的外部研究。信息传播核心将 利用广泛的区域和国家初级保健网络分享研究结果，积极寻求合作， 并发现其他 OAIC 和 NIA 中心之间研究和培训活动的规模经济。 西北OAIC将适时引入一个高度互补的重点领域，同时带来 大芝加哥社区和伊利诺伊州纳入国家胡椒中心网络。

ABSTRACT We propose an Older Americans Independence Center (OAIC) at Northwestern University. Its mission will be to: Generate innovative research that will enhance primary care for medically complex, older adults with multiple chronic conditions (MCC) to achieve optimal health, function, independence and quality of life. The Northwestern OAIC will catalyze research on: i) identifying modifiable clinical, healthcare system, and social environmental determinants of chronic disease outcomes, physical and mental health, and quality of life for older adults with MCC - especially those with frailty; ii) developing novel, practical, and scalable primary care management strategies that align with patient priorities, improve health outcomes and maintain independence for this vulnerable, at-risk, older adult population. The specific aims of the Northwestern OAIC are to: Aim 1 Formalize a comprehensive, multidisciplinary, aging research program dedicated to improving healthcare, functional independence, and quality of life for older adults with MCC. Aim 2 Expand Northwestern training and mentoring activities to develop future leaders in geriatrics and aging research who will transform healthcare to meet the needs of older adults with MCC. Aim 3 Stimulate applied research on the innovative design of primary care models that align with the priorities of older adults with MCC through aging-specific research resources and expertise in healthcare system & technology design (`Design Core'), patient-reported outcomes measurement (`Measurement Core') and quantitative & qualitative data analytics (`Analytics Core'). With strong institutional support and established infrastructure, we will organize internationally-recognized aging research faculty at Northwestern and establish a formal presence as a collaborative center on aging. Junior faculty with aging and MCC-related research interests will participate as mentored scientists; our OAIC will help them establish a successful career trajectory as independent investigators. Three essential Resource Cores (Design, Measurement, Analytics) will generate new methodological approaches for addressing MCC in primary care and facilitate designing and testing health system interventions via pilot and developmental projects, and through the use of an extensive portfolio of ongoing external studies. An Information Dissemination Core will leverage broad regional and national primary care networks to share findings, proactively seek collaborations, and find economies of scale in research and training activities among other OAICs and NIA centers. The Northwestern OAIC will introduce a timely and highly complementary area of focus, while bringing the greater Chicago community and Illinois into the national Pepper Center network.