The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern University

摘要 我们建议在西北大学建立一个老年美国人独立中心（OAIC）。其使命是： 产生创新的研究，将加强初级保健的医疗复杂，老年人与 多种慢性病（MCC），以实现最佳的健康，功能，独立性和生活质量。 西北OAIC将促进研究：i）确定可修改的临床，医疗保健系统， 慢性病结局、身心健康和生活质量的社会环境决定因素 对于患有MCC的老年人-特别是那些虚弱的人; ii）开发新颖，实用和可扩展的初级保健 符合患者优先事项的管理策略，改善健康结果并保持独立性 为这些脆弱的、有风险的老年人提供帮助。西北OAIC的具体目标是： 目标1形成一个全面的，多学科的，老龄化研究计划，致力于改善 医疗保健、功能独立性和老年MCC患者的生活质量。 目标2扩大西北培训和指导活动，以培养老年医学和老龄化的未来领导者 研究谁将改变医疗保健，以满足老年人与MCC的需求。 目标3：促进与优先事项相一致的初级保健模式创新设计的应用研究 通过特定年龄的研究资源和医疗保健系统的专业知识， 和技术设计（“设计核心”），患者报告的结果测量（“测量核心”） 定量和定性数据分析（“分析核心”）。 以强有力的制度支撑和已建立的基础设施，组织国际公认的老龄化 研究人员在西北大学，并建立一个正式的存在作为一个合作中心的老龄化。初级 具有老龄化和MCC相关研究兴趣的教师将作为指导科学家参加;我们的OAIC将帮助 他们作为独立调查员建立了成功的职业轨迹。三大核心资源 （设计、测量、分析）将产生新的方法， 通过试点和发展项目，关心和促进卫生系统干预措施的设计和测试， 通过使用正在进行的外部研究的广泛组合。信息传播核心将 利用广泛的区域和国家初级保健网络分享研究结果，积极寻求合作， 并在其他OAIC和NIA中心的研究和培训活动中发现规模经济。 西北OAIC将引入一个及时和高度互补的重点领域， 大芝加哥社区和伊利诺伊州加入全国胡椒中心网络。

ABSTRACT We propose an Older Americans Independence Center (OAIC) at Northwestern University. Its mission will be to: Generate innovative research that will enhance primary care for medically complex, older adults with multiple chronic conditions (MCC) to achieve optimal health, function, independence and quality of life. The Northwestern OAIC will catalyze research on: i) identifying modifiable clinical, healthcare system, and social environmental determinants of chronic disease outcomes, physical and mental health, and quality of life for older adults with MCC - especially those with frailty; ii) developing novel, practical, and scalable primary care management strategies that align with patient priorities, improve health outcomes and maintain independence for this vulnerable, at-risk, older adult population. The specific aims of the Northwestern OAIC are to: Aim 1 Formalize a comprehensive, multidisciplinary, aging research program dedicated to improving healthcare, functional independence, and quality of life for older adults with MCC. Aim 2 Expand Northwestern training and mentoring activities to develop future leaders in geriatrics and aging research who will transform healthcare to meet the needs of older adults with MCC. Aim 3 Stimulate applied research on the innovative design of primary care models that align with the priorities of older adults with MCC through aging-specific research resources and expertise in healthcare system & technology design (`Design Core'), patient-reported outcomes measurement (`Measurement Core') and quantitative & qualitative data analytics (`Analytics Core'). With strong institutional support and established infrastructure, we will organize internationally-recognized aging research faculty at Northwestern and establish a formal presence as a collaborative center on aging. Junior faculty with aging and MCC-related research interests will participate as mentored scientists; our OAIC will help them establish a successful career trajectory as independent investigators. Three essential Resource Cores (Design, Measurement, Analytics) will generate new methodological approaches for addressing MCC in primary care and facilitate designing and testing health system interventions via pilot and developmental projects, and through the use of an extensive portfolio of ongoing external studies. An Information Dissemination Core will leverage broad regional and national primary care networks to share findings, proactively seek collaborations, and find economies of scale in research and training activities among other OAICs and NIA centers. The Northwestern OAIC will introduce a timely and highly complementary area of focus, while bringing the greater Chicago community and Illinois into the national Pepper Center network.