The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern University

西北大学克劳德·D·佩珀美国老年人独立中心 (OAIC)

• 批准号: 10670159
• 负责人: Jeffrey A. Linder
• 金额: $ 141.63万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10670159
• 关键词: Acceleration; Address; Adult; Age; Aging; American; Applied Research; Area; Assessment tool; Capsicum; Caregivers; Caring; Chicago; Chronic Disease; Clinical; Collaborations; Collection; Communities; Complex; Data Analytics; Decision Making; Dedications; Development; Discipline; Disease Outcome; Elderly; Evidence based practice; Faculty; Future; Geriatrics; Government; Growth; Health; Health system; Healthcare; Healthcare Systems; Illinois; Information Dissemination; Infrastructure; Institution; International; Intervention; Investigation; Learning; Link; Managed Care; Measurement; Medical; Mental Health; Mentors; Mentorship; Methodology; Mission; Modeling; Outcome; Patient Outcomes Assessments; Patients; Pilot Projects; Population; Prevalence; Primary Care; Public Health; Quality of life; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Risk; Schools; Scientist; Self Management; Services; Technology; Testing; Training; Training Activity; Translating; Universities; burden of illness; career; career networking; clinical decision-making; cost effective; data harmonization; design; education research; frailty; functional independence; human old age (65+); improved; industry partner; innovation; interest; medical schools; multidisciplinary; multiple chronic conditions; novel; older patient; physical conditioning; primary care practice; primary care provider; programs; provider adherence; research faculty; risk stratification; social

ABSTRACT We propose an Older Americans Independence Center (OAIC) at Northwestern University. Its mission will be to: Generate innovative research that will enhance primary care for medically complex, older adults with multiple chronic conditions (MCC) to achieve optimal health, function, independence and quality of life. The Northwestern OAIC will catalyze research on: i) identifying modifiable clinical, healthcare system, and social environmental determinants of chronic disease outcomes, physical and mental health, and quality of life for older adults with MCC - especially those with frailty; ii) developing novel, practical, and scalable primary care management strategies that align with patient priorities, improve health outcomes and maintain independence for this vulnerable, at-risk, older adult population. The specific aims of the Northwestern OAIC are to: Aim 1 Formalize a comprehensive, multidisciplinary, aging research program dedicated to improving healthcare, functional independence, and quality of life for older adults with MCC. Aim 2 Expand Northwestern training and mentoring activities to develop future leaders in geriatrics and aging research who will transform healthcare to meet the needs of older adults with MCC. Aim 3 Stimulate applied research on the innovative design of primary care models that align with the priorities of older adults with MCC through aging-specific research resources and expertise in healthcare system & technology design (`Design Core'), patient-reported outcomes measurement (`Measurement Core') and quantitative & qualitative data analytics (`Analytics Core'). With strong institutional support and established infrastructure, we will organize internationally-recognized aging research faculty at Northwestern and establish a formal presence as a collaborative center on aging. Junior faculty with aging and MCC-related research interests will participate as mentored scientists; our OAIC will help them establish a successful career trajectory as independent investigators. Three essential Resource Cores (Design, Measurement, Analytics) will generate new methodological approaches for addressing MCC in primary care and facilitate designing and testing health system interventions via pilot and developmental projects, and through the use of an extensive portfolio of ongoing external studies. An Information Dissemination Core will leverage broad regional and national primary care networks to share findings, proactively seek collaborations, and find economies of scale in research and training activities among other OAICs and NIA centers. The Northwestern OAIC will introduce a timely and highly complementary area of focus, while bringing the greater Chicago community and Illinois into the national Pepper Center network.

摘要

项目成果

Non-Visit-Based and Non-Infection-Related Antibiotic Use in the US: A Cohort Study of Privately Insured Patients During 2016-2018.

美国非访问性和非感染相关抗生素的使用：2016 - 2018年期间对私人保险患者的队列研究。

• DOI: 10.1093/ofid/ofab412
• 发表时间: 2021-09
• 期刊: Open forum infectious diseases
• 影响因子: 4.2
• 作者: Fischer MA;Mahesri M;Lii J;Linder JA
• 通讯作者: Linder JA

Trends in Prepregnancy Obesity and Association With Adverse Pregnancy Outcomes in the United States, 2013 to 2018.

• DOI: 10.1161/jaha.120.020717
• 发表时间: 2021-09-07
• 期刊: Journal of the American Heart Association
• 影响因子: 5.4
• 作者: Wang MC;Freaney PM;Perak AM;Greenland P;Lloyd-Jones DM;Grobman WA;Khan SS
• 通讯作者: Khan SS

Cigarette Smoking and Competing Risks for Fatal and Nonfatal Cardiovascular Disease Subtypes Across the Life Course.

• DOI: 10.1161/jaha.121.021751
• 发表时间: 2021-12-07
• 期刊: JOURNAL OF THE AMERICAN HEART ASSOCIATION
• 影响因子: 5.4
• 作者: Khan, Sadiya S.;Ning, Hongyan;Sinha, Arjun;Wilkins, John;Allen, Norrina B.;Vu, Thanh Huyen T.;Berry, Jarett D.;Lloyd-Jones, Donald M.;Sweis, Ranya
• 通讯作者: Sweis, Ranya

Distribution and Correlates of Incident Heart Failure Risk in South Asian Americans: The MASALA Study.

• DOI: 10.1016/j.cardfail.2021.05.013
• 发表时间: 2021-11
• 期刊: Journal of cardiac failure
• 影响因子: 6
• 作者: Shah NS;Agarwal A;Huffman MD;Gupta DK;Yancy CW;Shah SJ;Kanaya AM;Ning H;Lloyd-Jones DM;Kandula NR;Khan SS
• 通讯作者: Khan SS

Dissemination of a long-term care planning tool, PlanYourLifespan.org, through community-based stakeholder leaders.

• DOI: 10.1111/jgs.17957
• 发表时间: 2022-11
• 期刊: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
• 影响因子: 6.3
• 作者: Lindquist, Lee A.;Wong, Norine;Forcucci, Chris;Rogers, Beverly;Ramirez, Ana;Ramirez-Zohfeld, Vanessa
• 通讯作者: Ramirez-Zohfeld, Vanessa