Administrative Core A

管理核心 摘要 管理核心的目的是在髓系中组织DF/HCC孢子的组成部分 并监督和领导这方面的科学、行政和财政方面 孢子。孢子董事本杰明·埃伯特博士和理查德·斯通博士将监督行政管理 协调本计划中概述的各种临床和实验室研究。他们将整合各种努力 在项目和核心内部和之间，从而促进结果的快速移动，使患者受益，因为 以及启动源于临床观察的实验室研究。这个孢子基础设施将 促进孢子白血病站点之间的关键通信和数据交换，以促进协作 临床前研究和临床试验。行政核心职能将包括组织会议。 以及外部顾问委员会、内部顾问委员会和治理委员会的指示。这个 管理委员会将负责招聘、审查和监督职业发展和 发展研究项目。行政核心将监测整个孢子的进展情况。这 将包括对项目和核心的监督。孢子主管将负责，与 促进发展项目转化为转化项目的治理委员会和/或终止 如果需要，一个翻译项目。该核心将促进两国之间的研究信息交流 DF/HCC内的孢子，引导与其他白血病孢子的协作和撤退，并传播 关于孢子内的临床开发奖和开发研究项目的信息 它本身。行政核心的具体目标是：1)监测研究项目和核心，并计划 未来；2)促进孢子内部和孢子之间的合作研究；3)整合 将髓系白血病中的孢子转化为DF/HCC结构；4)为财政提供必要的资源 监督；以及5)促进重大研究成果的快速传播。

Administrative Core Abstract The purpose of the administrative core is to organize the components of the DF/HCC Spore in Myeloid Malignancies and to provide oversight and leadership of the scientific, administrative, and fiscal aspects of this SPORE. The SPORE Directors, Dr. Benjamin Ebert and Dr. Richard Stone, will oversee the administrative coordination of the various clinical and laboratory studies outlined in this program. They will integrate efforts within and between projects and cores thereby promoting rapid movements of findings to benefit patients as well as the initiation of laboratory studies stemming from clinical observations. This SPORE infrastructure will facilitate critical communication and exchange of data between SPORE leukemia sites to facilitate collaborative pre-clinical studies and clinical trials. The administrative core functions will include organization of meetings and direction from the external advisory board, internal advisory board, and governance committee. The governance committee will be responsible for solicitation, review, and oversight of career development and developmental research projects. The administrative core will monitor the progress of the entire SPORE. This will include oversight of the projects and cores. The SPORE director will be responsible, in conjunction with the governance committee for promotion of developmental projects into translational projects and/or terminate a translational project if required. The Core will facilitate the interchange of research information between SPOREs within the DF/HCC, guide collaboration and retreats with other leukemia SPOREs, and disseminate information about the Clinical Development Awards and Developmental Research Projects within the SPORE itself. The Specific Aims of the Administration Core are: 1) to monitor research projects and Cores and plan for the future; 2) to foster collaborative research within the SPORE and between SPOREs; 3) to integrate the SPORE in Myeloid Leukemias into the DF/HCC structure; 4) to provide necessary resources for fiscal oversight; and 5) to promote rapid dissemination of significant research findings.