Administrative Core A

行政核心A

• 批准号: 10220871
• 负责人: Benjamin Levine Ebert
• 金额: $ 199.52万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-19 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10220871
• 关键词: Administrative Coordination; Area; Award; Boston; Cancer Center; Clinical; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Decision Making; Development; Discipline; Doctor of Medicine; Ensure; Evaluation; Fostering; Funding; Future; Individual; Infrastructure; Institution; Laboratory Study; Leadership; Malignant neoplasm of lung; Monitor; Movement; Multiple Myeloma; Myeloid Leukemia; Myeloproliferative disease; Ohio; Output; Patients; Principal Investigator; Reproduction spores; Research; Research Personnel; Research Project Grants; Resource Allocation; Resources; Site; Structure; Universities; Washington; Work; anticancer research; authority; career; career development; clinical development; data exchange; leukemia; malignant breast neoplasm; medical schools; meetings; member; novel therapeutic intervention; organizational structure; preclinical study; programs; stem; success; tool

Administrative Core Abstract The purpose of the administrative core is to organize the components of the DF/HCC Spore in Myeloid Malignancies and to provide oversight and leadership of the scientific, administrative, and fiscal aspects of this SPORE. The SPORE Directors, Dr. Benjamin Ebert and Dr. Richard Stone, will oversee the administrative coordination of the various clinical and laboratory studies outlined in this program. They will integrate efforts within and between projects and cores thereby promoting rapid movements of findings to benefit patients as well as the initiation of laboratory studies stemming from clinical observations. This SPORE infrastructure will facilitate critical communication and exchange of data between SPORE leukemia sites to facilitate collaborative pre-clinical studies and clinical trials. The administrative core functions will include organization of meetings and direction from the external advisory board, internal advisory board, and governance committee. The governance committee will be responsible for solicitation, review, and oversight of career development and developmental research projects. The administrative core will monitor the progress of the entire SPORE. This will include oversight of the projects and cores. The SPORE director will be responsible, in conjunction with the governance committee for promotion of developmental projects into translational projects and/or terminate a translational project if required. The Core will facilitate the interchange of research information between SPOREs within the DF/HCC, guide collaboration and retreats with other leukemia SPOREs, and disseminate information about the Clinical Development Awards and Developmental Research Projects within the SPORE itself. The Specific Aims of the Administration Core are: 1) to monitor research projects and Cores and plan for the future; 2) to foster collaborative research within the SPORE and between SPOREs; 3) to integrate the SPORE in Myeloid Leukemias into the DF/HCC structure; 4) to provide necessary resources for fiscal oversight; and 5) to promote rapid dissemination of significant research findings.

行政核心 摘要 管理核心的目的是组织骨髓中DF/HCC孢子的组分 并提供监督和领导的科学，行政和财政方面的这一点 孢子。孢子董事，本杰明·埃伯特博士和理查德·斯通博士，将监督行政 协调本计划中概述的各种临床和实验室研究。他们将努力整合 在项目和核心内部和之间，从而促进研究结果的快速移动， 以及启动源于临床观察的实验室研究。该SPORE基础设施将 促进SPORE白血病研究中心之间的关键沟通和数据交换，以促进协作 临床前研究和临床试验。行政核心职能将包括组织会议 以及外部咨询委员会、内部咨询委员会和治理委员会的指导。的 管理委员会将负责职业发展的征求、审查和监督， 发展研究项目。管理核心将监控整个SPORE的进度。这 将包括对项目和核心的监督。SPORE董事将负责与 促进发展项目转化为转化项目和/或终止 翻译项目，如果需要。该核心将促进研究信息的交流， DF/HCC中的SPORE，指导与其他白血病SPORE的合作和撤退，并传播 有关SPORE内的临床开发奖和开发研究项目的信息 本身行政核心的具体目标是：1）监督研究项目和核心，并计划 未来; 2）促进SPORE内部和SPORE之间的合作研究; 3）整合 骨髓性白血病的孢子进入DF/HCC结构; 4）为财政提供必要的资源 （5）促进重要研究成果的快速传播。