Resource Core (RC)

资源核心 (RC)

• 批准号: 10221534
• 负责人: Steven M Albert
• 金额: $ 18.54万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10221534
• 关键词: Affect; Aging; Agreement; American; Assessment tool; Assisted Living Facilities; Audiotape; Capsicum; Clinic; Clinical; Clinical Research; Clinical Trials; Clinical assessments; Cohort Studies; Collaborations; Communities; Computers; Consent; Consultations; Data Set; Databases; Development; Devices; Dissemination and Implementation; Elderly; Engineering; Enrollment; Equilibrium; Equipment; Fatty acid glycerol esters; Feedback; Fostering; Foundations; Funding; Grant; Health system; Image; Individual; Institution; Instruction; Interdisciplinary Study; Internet; Laboratories; Lead; Leadership; Libraries; Long-Term Care; Machine Learning; Manuscripts; Measurement; Methodology; Methods; Modeling; Muscle; Neighborhoods; Older Population; Outcome; Participant; Physical activity; Physical environment; Platinum; Population; Provider; Public Health; Publications; Registries; Research; Research Personnel; Research Training; Resources; Schools; Series; Services; Site; Skilled Nursing Facilities; Source; Specimen; Standardization; Study Subject; System; Technology; Testing; Training; Ultrasonography; actigraphy; base; design; dissemination strategy; experience; fall risk; falls; human subject; implementation efforts; innovation; interdisciplinary approach; interest; longitudinal dataset; member; neglect; novel; outreach; patient oriented; portability; programs; recruit; research study; screening; searchable database; secondary analysis; tool; usability; walkability

CPOC Summary/Abstract The Clinical and Population Outcomes Core (CPOC) promotes a multidisciplinary approach to the assessment of mobility and balance in OAIC clinical research through three key functions: (i) engaging older adults from the community and long-term care settings as participants (in a series of large-scale registries) and partners (through our Community Advisory Board) in research; (ii) providing training to investigators on appropriate contact, screening, and consent strategies for research with older populations; and (iii) sharing expertise in clinical assessment methodology (though a standardized library of assessment tools and study datasets) for mobility, balance, and falls. The Core has been highly productive. Over the past 5 years CPOC has provided support for 13 pilot or developmental projects, including consultation for 5 REC trainee pilots. Our support has contributed to 8 newly funded grants (4 R01, 2 K01, 1 VA, 1 foundation) and has supported over 40 independently funded external projects. CPOC support has resulted in over 200 publications. CPOC successfully launched the Platinum Long-Term Care Registry (seniors residing in assisted living and skilled nursing facilities who have consented to research contact), with over 40 facility recruitment sites and over 400 residents enrolled. The CPOC Community Registry includes over 2500 older participants and has served as a key recruitment source for 60 research studies. The CPOC SMART Center provides clinical research space and serves as a testbed for a number of innovative devices and experimental paradigms designed by the Integrative Systems Core, and our novel mobile laboratory utilizes noninvasive, portable technology to examine mobility, balance, and physical activity in the field. In the renewal we will 1) increase recruitment and researcher use of the Pepper Long-Term Care-Platinum and Community Registries, with streamlined web access and oversight; 2) expand dissemination-implementation efforts through a partnership with our PCORI- funded patient-oriented “Story Booth” program; 3) expand our mobile laboratory by adding additional investigative tools, including actigraphy and ultrasound assessment of muscle and fat; and 4) implement a developmental pilot, “Automated Neighborhood Walkability Audits by Machine Learning,” with colleagues in our School of Engineering to develop computer-based, automated methods for auditing Google Street View images for environmental features most relevant to mobility and falls in older adults. The proposed developmental pilot will provide important information on external physical environments, a neglected domain for falls risk. Leadership of the Core continues with Dr. Steven M. Albert and now includes Dr. Andrea Rosso, who will co-direct and also lead our developmental project.

CPOC 摘要/摘要 临床和人口结果核心 (CPOC) 提倡采用多学科方法进行评估 OAIC 临床研究中的活动性和平衡性通过三个关键功能进行：(i) 让老年人参与 社区和长期护理机构作为参与者（一系列大型登记处）和合作伙伴 （通过我们的社区咨询委员会）研究； (ii) 向调查人员提供适当的培训 老年人群研究的接触、筛查和同意策略； (iii) 分享以下方面的专业知识 临床评估方法（通过评估工具和研究数据集的标准化库） 活动能力、平衡能力和跌倒能力。核心的生产力非常高。过去5年CPOC提供了 支持 13 个试点或开发项目，包括为 5 名 REC 实习飞行员提供咨询。我们的支持有 贡献了 8 项新资助的赠款（4 R01、2 K01、1 VA、1 基金会），并支持了 40 多个项目 独立资助的外部项目。 CPOC 的支持已出版了 200 多篇出版物。 CPOC 成功启动了白金长期护理登记处（居住在辅助生活和技术熟练的老年人 同意研究接触的护理机构），拥有 40 多个机构招募地点和 400 多个 居民登记。 CPOC 社区登记处包括 2500 多名老年参与者，并作为 60 项研究的主要招募来源。 CPOC SMART中心提供临床研究空间 并作为许多创新设备和实验范例的测试平台 集成系统核心和我们新颖的移动实验室利用非侵入式便携式技术 检查现场的灵活性、平衡性和身体活动。在更新中，我们将 1) 增加招聘和 研究人员使用 Pepper 长期护理白金和社区注册中心以及简化的网络 访问和监督； 2) 通过与我们的 PCORI 合作扩大传播实施工作 资助以患者为中心的“故事摊位”计划； 3）通过添加额外的内容来扩展我们的移动实验室 研究工具，包括肌肉和脂肪的体动记录仪和超声评估； 4) 实施 与同事一起开发试点项目“通过机器学习进行自动社区步行能力审核” 我们的工程学院将开发基于计算机的自动化方法来审核 Google 街景 与老年人行动能力和跌倒最相关的环境特征图像。拟议的 发展试点将提供有关外部物理环境的重要信息，这是一个被忽视的领域 以防跌倒风险。核心领导层继续由 Steven M. Albert 博士领导，现在包括 Andrea Rosso 博士， 谁将共同指导并领导我们的发展项目。