BIDIRECTIONAL TRAINING TO ENHANCE CANCER RESEARCH CAPACITY IN AFRICA

项目概要/摘要 预计未来两年，撒哈拉以南非洲（SSA）的癌症死亡率将增加一倍以上。 几十年这场公共卫生危机要求建立一个知识库，以便更好地理解和采取行动 关于SSA中日益增长的癌症负担。我们提出了一个训练计划，将最大限度地提高癌症的严格性， 通过培训研究人员来发展战略和业务能力， 了解癌症风险和结果的决定因素，并提高 降低风险，改善结果。本培训计划的总体目标是：1）开发和 传播最佳做法，使非洲能够进行最高质量的癌症研究; 2）教授基本技能 在非洲进行研究的人; 3）建立一个能够领导和支持癌症的个人骨干队伍 研究在SSA。我们的培训计划提出了以下具体目标：1）制定和实施 教育和职业发展计划，将最大限度地提高研究的严谨性正在进行的SSA; 2)招募和培训能够在癌症研究中建立可持续职业生涯的个人; 3）评估 该培训计划对学员和参与者的职业成果。学员将分为两组。 首先，我们为博士水平的研究者提出了一个主要研究者（PI）轨道，他们将接受培训， 在独立和合作研究中发挥领导作用。PI Track的参与者将成为 精通研究监督和治理，并建立技能和科学项目的重点， 独立的校外资助。第二，将实施项目管理（PM）轨道， 支持开展研究。PM Track的参与者将有资格支持各种研究 在卫生和监管环境中的项目。培训将涉及导师之间的双边互动 以及在SSA和美国的受训人员，他们将合作开发和实施最佳研究实践。的 培训计划将建立在非常成功的现有研究网络在SSA：非洲乳腺癌 研究（ABCS），非洲食管癌联合会（AFRECC），非洲研究小组， 非洲裔男性和前列腺癌网络（MADCaP）。 在这些网络的导师和研究能力的基础上，拟议的计划将提供一个核心 非洲项目管理监督培训和教育研究课程 （PROMOTE-AFRICA）框架以及基于项目的（PI轨道）或基于实践的（PM 轨道）活动以及其他教育经验，以个人寻求职业生涯作为独立的癌症 研究人员或项目经理。

PROJECT SUMMARY/ABSTRACT Cancer mortality rates are projected to more than double in Sub-Saharan Africa (SSA) in the next two decades. This public health crisis requires that a knowledge base be developed to better understand and act on the growing cancer burden in SSA. We propose a training program that will maximize the rigor of cancer research in SSA by training researchers to develop strategic and operational capacity that will generate new knowledge about the determinants of cancer risk and outcomes and improve effectiveness of strategies for reducing risk and improve outcomes. The overarching goals of this training program are to 1) Develop and disseminate best practices to enable the highest quality cancer research in Africa; 2) Teach fundamental skills to those who conduct research in Africa; and 3) Create a cadre of individuals who can lead and support cancer research in SSA. Our training program proposes the following specific aims: 1) Develop and implement an educational and career development program that will maximize the rigor of research being conducted in SSA; 2) Recruit and train individuals who can build sustainable careers in cancer research; 3) Assess the impact of this training program on the career outcomes of trainees and participants. Trainees will fall into two groups. First, we propose a Principal Investigator (PI) Track for doctoral level investigators who will be trained to demonstrate leadership in independent and collaborative research. Participants in the PI Track will become proficient in research oversight and governance and build the skills and a scientific project focus toward independent extramural grant funding. Second, a Project Management (PM) Track will be implemented to support the conduct of research. Participants in the PM Track will be qualified to support a variety of research projects within SSA health and regulatory settings. Training will involve bilateral interactions between mentors and trainees in both SSA and the US who will partner to develop and implement best research practices. The training program will build on highly successful existing research networks in SSA: The African Breast Cancer Study (ABCS), The African Esophageal Cancer Consortum (AFRECC), The African Research Group in Oncology (ARGO), and the Men of African Descent and Carcinoma of the Prostate (MADCaP) network. Building on mentors and research capacity of these networks, the proposed program will provide a core research curriculum known as the PROject Management Oversight Training and Education in AFRICA (PROMOTE-AFRICA) framework as well as project-based (for the PI Track) or practicum-based (for the PM track) activities as well as other educational experiences to individuals seeking careers as independent cancer researchers or project managers.