BIDIRECTIONAL TRAINING TO ENHANCE CANCER RESEARCH CAPACITY IN AFRICA

项目摘要/摘要 预计未来两年撒哈拉以南非洲地区的癌症死亡率将增加一倍以上 几十年。这一公共卫生危机要求建立一个知识库，以便更好地理解和采取行动 关于SSA不断增长的癌症负担。我们提出了一项培训计划，将最大限度地提高癌症的严谨性 通过培训研究人员来开发战略和运营能力，从而产生新的 了解癌症风险和结果的决定因素，并提高战略的有效性 降低风险，改善结果。该培训计划的总体目标是：1)开发和 传播最佳实践，促进非洲最高质量的癌症研究；2)教授基本技能 给那些在非洲进行研究的人；以及3)培养一支能够领导和支持癌症的个人干部队伍 在SSA中进行研究。我们的培训计划提出了以下具体目标：1)制定和实施 教育和职业发展计划，将最大限度地提高SSA正在进行的研究的严谨性； 2)招募和培训能够在癌症研究领域建立可持续职业生涯的个人；3)评估 这项培训计划是关于受训者和参与者的职业生涯成果。受训人员将分成两组。 首先，我们建议为博士生级别的研究人员设立首席调查员(PI)轨道，他们将接受培训 在独立和协作研究方面表现出领导力。PI路径的参与者将成为 精通研究监督和治理，并培养技能和专注于科学项目 独立的校外赠款资金。第二，将实施项目管理(PM)跟踪，以 支持开展研究。PM项目的参与者将有资格支持各种研究 在SSA健康和监管环境下的项目。培训将包括导师之间的双边互动 以及SSA和美国的受训人员，他们将合作开发和实施最佳研究实践。这个 培训计划将建立在SSA：非洲乳腺癌非常成功的现有研究网络的基础上 非洲食道癌联合会(AFRECC)，非洲研究小组 肿瘤学(ARGO)和非洲人后裔和前列腺癌(MADCAP)网络。 在这些网络的导师和研究能力的基础上，拟议的方案将提供一个核心 被称为非洲项目管理监督培训和教育的研究课程 (促进非洲)框架以及以项目为基础(对于PI轨道)或以实践为基础(对于项目管理 Track)活动以及其他教育经验对寻求独立癌症职业的个人 研究人员或项目经理。

PROJECT SUMMARY/ABSTRACT Cancer mortality rates are projected to more than double in Sub-Saharan Africa (SSA) in the next two decades. This public health crisis requires that a knowledge base be developed to better understand and act on the growing cancer burden in SSA. We propose a training program that will maximize the rigor of cancer research in SSA by training researchers to develop strategic and operational capacity that will generate new knowledge about the determinants of cancer risk and outcomes and improve effectiveness of strategies for reducing risk and improve outcomes. The overarching goals of this training program are to 1) Develop and disseminate best practices to enable the highest quality cancer research in Africa; 2) Teach fundamental skills to those who conduct research in Africa; and 3) Create a cadre of individuals who can lead and support cancer research in SSA. Our training program proposes the following specific aims: 1) Develop and implement an educational and career development program that will maximize the rigor of research being conducted in SSA; 2) Recruit and train individuals who can build sustainable careers in cancer research; 3) Assess the impact of this training program on the career outcomes of trainees and participants. Trainees will fall into two groups. First, we propose a Principal Investigator (PI) Track for doctoral level investigators who will be trained to demonstrate leadership in independent and collaborative research. Participants in the PI Track will become proficient in research oversight and governance and build the skills and a scientific project focus toward independent extramural grant funding. Second, a Project Management (PM) Track will be implemented to support the conduct of research. Participants in the PM Track will be qualified to support a variety of research projects within SSA health and regulatory settings. Training will involve bilateral interactions between mentors and trainees in both SSA and the US who will partner to develop and implement best research practices. The training program will build on highly successful existing research networks in SSA: The African Breast Cancer Study (ABCS), The African Esophageal Cancer Consortum (AFRECC), The African Research Group in Oncology (ARGO), and the Men of African Descent and Carcinoma of the Prostate (MADCaP) network. Building on mentors and research capacity of these networks, the proposed program will provide a core research curriculum known as the PROject Management Oversight Training and Education in AFRICA (PROMOTE-AFRICA) framework as well as project-based (for the PI Track) or practicum-based (for the PM track) activities as well as other educational experiences to individuals seeking careers as independent cancer researchers or project managers.